Results 121 to 130 of about 5,010,147 (298)

The Impact of Triglyceride-Glucose Index Trajectories on Incidence and Recurrent Cardiovascular Events: Evidence from a Retrospective Cohort Study

Vascular Health and Risk Management
Yuan Xu,1,* Gonglong Wu,2,* Long Jiang,3 Xinlei Yang,1 Chengjin Wen,4 Yulan Yang,5 Hui Hu6 1Medical Big Data Center, The Second Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of China; 2School of Public Health ...
Xu Y, Wu G, Jiang L, Yang X, Wen C, Yang Y, Hu H   +6 more
doaj  

Hemoglobin glycation index and triglyceride-glucose index are related to diabetic nephropathy

Cirugía y Cirujanos (English Edition)
Diabetic nephropathy (DN) is a significant complication of diabetes. Despite strict management of fasting plasma glucose (FPG), DN may progress to end-stage renal disease. HbA1c, the best biomarker for glycemic management, may differ in similar FPG. Hemoglobin glycation index (HGI) = HbA1c as determined minus HbA1c as predicted.
openaire   +2 more sources

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić, Christina Antza, Anastasios Poutachidis, Smaro Palaska, Elvira Meni Maria Gkrinia, Andrea Katrin Faour, Yusuf Ziya Sener, Seher Sener, Rehena Sultana   +8 more
wiley   +1 more source

Triglyceride-glucose index association with severity of coronary artery disease

BackgroundDespite previous studies, the relationship between the triglyceride-glucose (TyG) index and coronary artery disease (CAD) is still undetermined.
M Marousi (21646766), M Ghayour-Mobarhan (16149035), P Salehi-Sangani (21483323), M Tajfard (16193183), F Imanparast (21646763), S Saffar Soflaei (21298907), Gordon Ferns (4464037), Z Fallahi (21480530), M Moohebati (16148996)   +8 more
core  

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source

Association of the triglyceride-glucose index and its related parameters with frailty

Lipids in Health and Disease
Background Frailty is a dynamic geriatric condition. Limited studies have examined the association of the triglyceride-glucose (TyG) index and its related indicators [TyG index, triglyceride glucose-waist to height ratio (TyG-WHtR), triglyceride glucose ...
Huangyi Yin, Liuqing Guo, Wei Zhu, Weishan Li, Yubo Zhou, Wenyun Wei, Min Liang   +6 more
doaj   +1 more source

Triglyceride-glucose index and triglyceride-glucose–body mass index as prognostic factors for early stage breast cancer patients receiving neoadjuvant chemotherapy

Translational Oncology
Background: Insulin resistance (IR) is closely associated with the risk of breast cancer. The triglyceride-glucose (TyG) index and the triglyceride-glucose–body mass index (TyG-BMI) are considered surrogate indicators of IR; however, their prognostic ...
Fucheng Li, Tian Gao, Zhaoting Li, He Dou, Yuling Ba, Siyuan Jia, Danli Luo, Min Xiao   +7 more
doaj   +1 more source

Clozapine:norclozapine ratio as a marker of metabolic risk and therapeutic response and effect of valproate on clozapine levels

British Journal of Clinical Pharmacology, EarlyView.
Aims Clozapine is the most effective antipsychotic in treatment‐resistant schizophrenia. Clozapine causes weight gain and increased diabetes risk. The role of its metabolite norclozapine and clozapine:norclozapine ratio (CLZ/NCLZ) in metabolic effects has been debated.
Susanna Maria Rask, Miina Lamminmäki, Olli Kampman, Mari Hämäläinen, Eeva Moilanen, Niko Seppälä, Anssi Solismaa   +6 more
wiley   +1 more source

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

Hepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran, Charlotte Wilhelmina Wernberg, Mette Munk Lauridsen, Maria Kløjgaard Skytthe, Sofie Marchsteiner Bendixen, Frederik Tibert Larsen, Camilla Dalby Hansen, Lea Ladegaard Grønkjær, Majken Storm Siersbæk, Tina Di Caterino, Sönke Detlefsen, Holger Jon Møller, Lars Grøntved, Kim Ravnskjaer, Søren Kragh Moestrup, Maja Sofie Thiele, Aleksander Krag, Jonas Heilskov Graversen   +17 more
wiley   +1 more source