Results 141 to 150 of about 5,010,147 (298)

A Novel Marker Triglyceride Glucose Index in Predicting the Development of No-reflow in Acute Coronary Syndrome without ST-segment Elevation [PDF]

Aim:The triglyceride-glucose (TyG) index is a new marker that predicts adverse clinical outcomes in coronary artery disease. We aimed to investigate the relationship between the TyG index and the no-reflow phenomenon after percutaneous coronary ...
Mehmet Koseoglu, Mehmet Altunova
core   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Lipid Subclasses Differentiate Insulin Resistance by Triglyceride–Glucose Index

Metabolites
Background: Insulin resistance is a key driver of metabolic syndrome and related disorders, yet its underlying metabolic alterations remain incompletely understood.
Khaled Naja, Najeha Anwardeen, Omar Albagha, Mohamed A. Elrayess   +3 more
doaj   +1 more source

The triglyceride-glucose index and C-reactive protein-triglyceride-glucose index as surrogate markers of vascular stiffness in prediabetes: a cross-sectional study

BMC Cardiovascular Disorders
Prediabetes accelerates arterial stiffening, yet the optimal metabolic biomarker for vascular assessment remains undetermined. This study investigated the associations of the homeostasis model assessment of insulin resistance (HOMA-IR), triglyceride-glucose (TyG) index, and C-reactive protein-triglyceride-glucose index (CTI) with arterial stiffness in ...
Guorang Qiu, Xuhong Li, Li Jiang, Yanhua Zhou, Jiaojiao Liu, Kui Chen, Xiaoling Zhu, Yaqin Wang   +7 more
openaire   +2 more sources

Triglyceride-glucose index in adolescents with type 1 diabetes mellitus

Diabetes Research and Clinical Practice
Even though HbA1c can be obtained easily and accurately by blood test, the cost may limit its availability for some patients and their proper follow-up. The triglyceride-glucose index has been shown to have an association with HbA1c in other populations, but it hasn't been studied in adolescents with T1DM yet.
Marta García-Poblet, Ana Pilar Nso-Roca, José Miguel Martínez-Sanz, Isabel Sospedra   +3 more
openaire   +4 more sources

The influence of circadian variables on ecotoxicology metabolomics

Biological Reviews, EarlyView.
ABSTRACT Ecotoxicologists are using metabolomics increasingly to gain insight into toxicological mechanisms and sublethal effects of chemical exposures. Metabolomics offers a sensitive multi‐parameter approach that can detect biochemical responses not obvious using apical and behavioural endpoints.
Ryan I. Lester, David J. Beale, Anthony R. Carroll, Steven D. Melvin   +3 more
wiley   +1 more source

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

Hepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol, Antoine Rimbert, Justina C. Wolters, Marieke Smit, Vincent W. Bloks, Niels J. Kloosterhuis, Nicolette C. A. Huijkman, Mirjam H. Koster, Umesh Tharehalli, Simon M. de Neck, Colin Bournez, Marceline M. Fuh, Jeroen Kuipers, Sujith Rajan, Alain de Bruin, Henry N. Ginsberg, Gerard J. P. van Westen, M. Mahmood Hussain, Ludger Scheja, Joerg Heeren, Philip Zimmerman, Bart van de Sluis, Jan Albert Kuivenhoven   +22 more
wiley   +1 more source

Association Between Triglyceride Glucose Index and Infertility in Reproductive-Aged Women: A Cross-Sectional Study [PDF]

Jiaru Zhuang,1,2 Shan Wang,1 Yuan Wang,1 Renjing Hu,2 Yibo Wu1 1Human Reproductive Medicine Center, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, 214026, People’s Republic of China; 2Department of Laboratory Medicine, Jiangnan University ...
Wang S, Wang Y, Hu R, Zhuang J, Wu Y
core  

Lipid droplet profiling during neutrophil differentiation by stimulated Raman scattering microscopy

Biotechnology Progress, EarlyView.
Abstract Lipid droplets (LDs) are dynamic organelles that serve as metabolic hubs and emerging regulators of immune cell fate. Although LDs have been implicated in immune regulation, how LD metabolism is remodeled during neutrophil differentiation and how stage‐specific LD dynamics shape mature neutrophil function remain poorly defined.
Ting‐Jung Sung, Bin Dong, Jingqiao Shen, Yan Tan, Chi Zhang, Xiaoping Bao   +5 more
wiley   +1 more source