Results 151 to 160 of about 5,010,147 (298)

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source

The Interplay Between Obesity and Triglyceride-Glucose Index in Modulating Parkinson’s Disease Risk: A Cross-Sectional NHANES Study of Middle-Aged and Young Adults

The Interplay Between Obesity and Triglyceride-Glucose Index in Modulating Parkinson’s Disease ...
ma, jincheng
core   +1 more source

The Effect of the MTHFR C677T Genotype Polymorphism on the Efficacy of Folic Acid Treatment for Hyperhomocysteinemia and Cardiovascular Endothelial Function

Chronic Diseases and Translational Medicine, EarlyView.
Flowchart of patient enrollment. ABSTRACT Background Cardiovascular disease remains a major public health burden. This study aimed to investigate the effect of the methylenetetrahydrofolate reductase (MTHFR) C677T genotype on folic acid treatment response and cardiovascular endothelial function in patients with hyperhomocysteinemia (HHcy).
Xiaohui Dou, Xijuan Zhang, Liang Zeng, Liheng Zeng, Xiaoyan Hu, Xuhong Jiang, Yahui Wan, Mingxia Ge, Xiaoyan Huang   +8 more
wiley   +1 more source

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

Hepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger, Holly E. Holmes, Tina Hu‐Seliger, Rodney W. Butt, Stephen A. Harrison, Dariush Mozaffarian, Oliver Chen, Leonard Guarente   +7 more
wiley   +1 more source

Short‐Term Effects of Golden Rice Cookies Enriched With Piper crocatum Extract on Lipid Profiles in Adults With Diabetes: A Quasi‐Experimental Study

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) commonly coexists with dyslipidemia and elevated cardiovascular risk. Food‐based interventions containing antioxidants and polyphenols may support lipid metabolism. This study evaluated the short‐term effects of Golden Rice cookies enriched with active Piper crocatum extract on lipid profiles in adults with DM.
Altje Suwardi Abram, Andina Setyawati, Andi Masyitha Irwan   +2 more
wiley   +1 more source

Development and validation of a machine learning-based sarcopenia prediction model using the triglyceride glucose–frailty index

Journal of International Medical Research
Objective Sarcopenia is a progressive skeletal muscle disorder characterized by declines in muscle mass and function. This study developed a novel composite biomarker, the triglyceride glucose–frailty index, which integrates metabolic and frailty-related
Wang Xiang, Houcheng Zhu, Xiandong Liu, Qingsong Wu   +3 more
doaj   +1 more source

Impact of Drone Versus Car Transport on Anti‐Doping Sample Integrity Over Short Distances: A Proof‐Of‐Concept Study

Drug Testing and Analysis, EarlyView.
This proof‐of‐concept study evaluated the impact of short‐distance drone transport on anti‐doping sample integrity compared with traditional car transport. Targeted assays and untargeted metabolomics revealed equivalent biological profiles between methods, confirming that drone delivery preserves sample integrity for the athlete biological passport ...
I. Al‐Mohannadi, M. Y. Al‐Jaber, M. Al‐Nesf, W. Samsam, Abdulaziz Farooq, N. M. Thomas, M. Stuart, N. Robinson, G. Zangenfeind, D. Rovira, N. Mohamed‐Ali, A. Beotra, V. Mohamed‐Ali, M. Al‐Maadheed   +13 more
wiley   +1 more source

Association Between Triglyceride-Glucose Index and Gout in Young Adults in China [PDF]

Cong Huang,1,2 Xiaodong Gu,3 Sudong Liu,3 Honghui Luo,2 Yiqun Luo,2 Yu Zhang1,2 1Meizhou Clinical Institute, Shantou University Medical College, Meizhou, 514000, People’s Republic of China; 2Department of General Medicine, Meizhou People′s Hospital ...
Huang C, Gu X, Zhang Y, Luo Y, Liu S, Luo H   +5 more
core  

Cognitive Behavioral Therapy for Binge‐Eating Disorder in Individuals With Type 2 Diabetes: A Pilot Randomized Controlled Trial

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To evaluate the feasibility of a randomized pilot trial of group‐based cognitive behavioral therapy (CBT) for binge eating disorder (BED) in individuals with type 2 diabetes, and to estimate exploratory clinical outcomes to inform the design of a future efficacy trial. Method Thirty‐four participants with type 2 diabetes and BED were
Pernille Fiil Nybo, Michael Einar Røder, Mia Beck Lichtenstein, René Klinkby Støving, Jakob Linnet   +4 more
wiley   +1 more source

Prognostic Value of the Triglyceride-Glucose Index Combined with Non-HDL-C/HDL-C Ratio for Predicting Coronary Microvascular Dysfunction in ACS Patients Post-PCI [PDF]

Sitong Hang,1,* Nan Tang,2,* Kangming Li,2 Qingdui Zhang,2 Ji Hao,2 Yan Zhang,2 Chunmei Qi2 1China Medical University, Shenyang, Liaoning, 110000, People’s Republic of China; 2Department of Cardiology, The Second Affiliated Hospital of Xuzhou ...
Hang S, Hao J, Tang N, Zhang Y, Li K, Qi C, Zhang Q   +6 more
core