Results 121 to 130 of about 5,723,129 (297)

ALDH2 Deficiency Promotes Mitochondrial Oxidative Stress and Adverse Limb Outcomes via VDAC–HSP60 Signaling

Advanced Science, EarlyView.
ALDH2 deficiency promotes 4‐HNE accumulation, resulting in covalent modification of HSP60, disruption of its oligomeric assembly, and VDAC1‐dependent release of HSP60 from mitochondria to the cytosol. Pharmacological activation of ALDH2 preserves HSP60 proteostasis and mitochondrial integrity, whereas the clinical association between the ALDH2 rs671 ...
You‐Cheng Lin, Nan‐Chun Wu, Chon‐Seng Hong, Po‐Chao Hsu, Wen‐Jin Yang, Yi‐Cheng Chang, Che‐Hong Chen, Wei‐Ting Chang   +7 more
wiley   +1 more source

Association of triglyceride-glucose index and its combinations with sarcopenia among community-dwelling older adults: based on the Chongqing Aging and Sarcopenia Evaluation (CHASE) cohort

Frontiers in Physiology
BackgroundThe triglyceride-glucose (TyG) index serves as an alternative index for assessing insulin resistance (IR). The relationship between the TyG index and its combined indicators and sarcopenia remains insufficiently explored.AimTo investigate the ...
Xinyu Yu, Siqi Jiang, Zhiyu Chen, Keke Ren, Shan Li, Yetao Luo, Deqing Chen, Qinghua Zhao, Huanhuan Huang   +8 more
doaj   +1 more source

Hepatic morphology and serum biochemical profile according to dry and rainy seasons in Pygocentrus nattereri (Characiformes: Serrasalmidae)

The Anatomical Record, EarlyView.
Abstract This study investigated the physiological and morphological adaptations of the liver of the carnivorous fish Pygocentrus nattereri (piranha) in response to seasonal variations (dry and rainy seasons) in the Brazilian Pantanal. The objective was to describe how the liver, a central organ in metabolic regulation, responds to environmental ...
Maria Eduarda Corona Garcia, Sandriely F. Marcondes, Mayara S. Siqueira, Taynara R. F. Leão, Robson A. Rodrigues, Karine N. N. Farias, André L. N. Silva, Karin Virgínia Kuibida, Lilian Franco‐Belussi, Carlos E. Fernandes   +9 more
wiley   +1 more source

Association of triglyceride-glucose index and triglyceride–glucose–body mass index with all-cause mortality in critically ill patients with aortic disease: A retrospective cohort study

JTCVS Open
Objective: Aortic diseases represent a group of life-threatening vascular disorders that impose a substantial socioeconomic burden. This study aimed to investigate the association between insulin resistance indices and all-cause mortality in with aortic ...
Jie Liu, MD, Zhaoxin Qian, MD, PhD, Jing Cao, MD, PhD   +2 more
doaj   +1 more source

Is the triglyceride-glucose index ready for cardiovascular risk assessment?

Nutrition, Metabolism and Cardiovascular Diseases
Insulin resistance is a major risk factor for cardiovascular disease. Thus, early identification of insulin resistance is important for classifying individuals at high cardiovascular risk. All the tools commonly used in epidemiological studies and clinical practice to assess insulin resistance require measuring insulin levels, which is a limitation ...
openaire   +3 more sources

Comparative Meta‐Analysis of Antimicrobial Peptides in Aquatic and Terrestrial Livestock Species

Animal Research and One Health, EarlyView.
A global meta‐analysis of 58 studies (926 effect sizes and 29 species across five taxa) revealed that dietary antimicrobial peptides generally improve growth performance, blood metabolites, and immune responses. The greatest benefits were observed in omnivorous livestock, such as pigs and chickens. Dose‐duration effects were evident. An optimal outcome
Lily Liu, Xu Luo, Qin Zhang, Jinhai Wang, Alan E. Wilson   +4 more
wiley   +1 more source

Association between triglyceride-glucose index and its correlation indexes and stress urinary incontinence in postmenopausal women: evidence from NHANES 2005–2018

Lipids in Health and Disease
Background Postmenopausal women are more susceptible to stress urinary incontinence (SUI), and insulin resistance (IR) is closely related to SUI. The triglyceride-glucose (TyG) index is an efficient metric for assessing IR.
Xueping Huang, Wen Hu, Limei Li
doaj   +1 more source

Association Between Triglyceride-Glucose Index and Hearing Threshold Shifts of Adults in the United States: National Health and Nutrition Examination Survey, 2015–2016 [PDF]

Jia-Ying Pan,1,* Yuan Chen,1,* Zhi-He Lin,1 Bo Lv,1 Lei Chen,2 Shao-Yan Feng1 1Department of Otorhinolaryngology, Head and Neck Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, Guangdong, People’s Republic of China ...
Feng SY, Lin ZH, Chen L, Lv B, Chen Y, Pan JY   +5 more
core  

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu, I. A. Anjola, L. O. Fasasi, D. P. Fadipe, A. T. Afuye, F. O. Fasanya, O. E. Oke   +6 more
wiley   +1 more source

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source