Results 111 to 120 of about 5,723,129 (297)

Engineered Chiral Probiotics Ameliorate MASH via Gut–Liver Axis

Advanced Science, EarlyView.
A chiral gold nanozyme was coated onto the gut commensal bacterium Faecalibacterium duncaniae (F. duncaniae) to create an engineered probiotic. In mouse models of MASH, this orally administered living therapeutic protected the bacterium against oxidative stress, enhanced its gut colonization, reversed steatosis, inflammation, and fibrosis, and improved
Jing Chen, Shen Zhang, Yuli Zhu, Da Zhou, Chunya Ji, Mingrui Zhu, Sirui Wang, Yuting Shen, Jifeng Yu, Heng Zhang, Yan Fang, Huixiong Xu, Haohao Yin   +12 more
wiley   +1 more source

Correlation of triglyceride glucose-body mass index, triglyceride glucose/high-density lipoprotein cholesterol ratio, and triglyceride glucose index with blood sugar and hemoglobin A1C in patients with type 2 diabetes mellitus: A cross-sectional study

Asian Journal of Medical Sciences
Background: Type 2 diabetes mellitus (T2DM) is one of the most common endocrine diseases characterized by increased blood glucose. Uncontrolled diabetes is associated with the development of micro- and macrovascular complications. Aims and Objectives:
Srikanth Akula , Swetha Akkina , Gandham Rajeev , Preethi Batakala , Bhagyalakshmi Atla , Sunkara Uha Priya , Divija Reddy Bonthu   +6 more
doaj   +1 more source

pH‐Responsive Nanoplatform‐Mediated Lipid Hijacking and Metabolic Collapse for Synergistic Starvation‐Immunotherapy

Advanced Science, EarlyView.
A pH‐responsive ZIF‐8/2‐DG@Cu‐TA nanoplatform orchestrates multifaceted metabolic disruption for synergistic starvation‐immunotherapy. Acid‐triggered 2‐DG release blocks glycolysis, while Zn2+ overload induces mitochondrial dysfunction. Concurrently, Cx43‐mediated gap junctions redirect lipid droplets from tumor cells to cancer‐associated fibroblasts ...
Xianlong Zong, Haochen Yao, Danyang Shen, Furu Gong, Zixuan Wang, Haoyang Qin, Yang Yang, Ruirui Qiao, Yongjuan Li, Rui Li   +9 more
wiley   +1 more source

Role of Triglyceride-Glucose Index in Type 2 Diabetes Mellitus and Its Complications [PDF]

Ying Pan,1 Mengjie Zhao,1 Tiantian Song,2 Jia Tang,2 Ming Kuang,2 Hongying Liu,2,* Shao Zhong3,* 1Department of General Practice, Kunshan Hospital Affiliated to Jiangsu University, Kunshan, Jiangsu, People’s Republic of China; 2Hangzhou Kang Ming
Liu H, Tang J, Zhao M, Pan Y, Zhong S, Song T, Kuang M   +6 more
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Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

Advanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin, Jian Lyu, Yanci Liu, Zhiyuan Feng, Jie Bao, Wenxiong Song, Bingcheng Zhu, Minghao Liu, Jionghao Xue, Jiadi Weng, Jiani Zhang, Jizong Zhao, Xiaolin Chen, Bin Dong   +13 more
wiley   +1 more source

Triglyceride glucose index versus triglyceride glucose-BMI index in non-alcoholic fatty liver disease: A correlation with steatosis and fibrosis

Bioinformation
Non-alcoholic fatty liver disease (NAFLD) links to insulin resistance and cardiometabolic risk, yet cost-effective markers like TyG and TyG-BMI indices for predicting steatosis and fibrosis severity remain under-evaluated in resource-limited settings.
Joshi, Aditya, Tangadi, Deepak, Tiwari, Ankit Kumar   +2 more
openaire   +3 more sources

The Impact of the Triglyceride-Glucose Index on the Development of Depression in Patients with Coronary Atherosclerotic Heart Disease [PDF]

Jing Guan,1 Yue Wang,1 Changjun Dong,1 Yuwen Chen,1 Bingqing Li,1 Yilu Zhou,1 Fanke Huang,1 Peiyuan Sun,1,2 Xue Tian,1,2 Feng Ran,1,2 Jianfeng Lv2 1ChinaThree Gorges University, Yichang, People’s Republic of China; 2Department of Cardiology, Affiliated ...
Lv J, Huang F, Guan J, Sun P, Ran F, Tian X, Chen Y, Li B, Wang Y, Zhou Y, Dong C   +10 more
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Injectable Peptide‐Based Functional Amyloid Hydrogels as Tunable Depots for Sustained Drug Delivery

Advanced Science, EarlyView.
An injectable and tunable peptide‐based functional amyloid hydrogel provides sustained insulin release while preserving insulin stability and bioactivity. The hydrogel enables prolonged glycemic regulation in vivo, exhibits excellent biocompatibility, and shows no detectable IAPP and α‐Syn heterologous cross‐seeding, highlighting its potential as a ...
Ranjit Shaw, Niyamat M. A. Chimthanawala, Shouvik Manna, Sadhana Sathaye, Samir K. Maji   +4 more
wiley   +1 more source

Triglyceride-glucose index, plasma metabolome and aortic stenosis: a Mendelian randomization analysis

Journal of Cardiothoracic Surgery
Background and Aims The association between the Triglyceride-Glucose index, an emerging marker of insulin resistance, and the risk of aortic stenosis remains unclear.
Zhisheng Yan, Yikang Wang, Xiaomei Dai, Qing Chang   +3 more
doaj   +1 more source

Triglyceride-glucose index and its association with depressive symptoms in older adults: a longitudinal analysis

Triglyceride-glucose index and its association with depressive symptoms in older adults: a longitudinal ...
CF Reynolds (14529389), RL Woods (14594627), Mohammadreza Mohebbi (13085409), Adrienne O'Neil (13088034), Michael Berk (13060851), JJ McNeil (12372043), Mojtaba Lotfaliany Abrand Abadi (13085616), Malcolm Forbes (13085907)   +7 more
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