Validation of Immunoassays for Total Thyroxine and Free Thyroxine and Age and Sex-Related Variation in Thyroid Hormone Serum Concentrations in Orangutans (Pongo sp.). [PDF]
J Med PrimatolABSTRACT Background Thyroid disease is reported in orangutans, but to properly diagnose and manage these disorders, reference intervals for circulating thyroid hormones are needed. Methods Commercial immunoassay kits for total thyroxine (TT4) and free thyroxine (FT4) were validated for use in orangutans (Pongo spp.).
Fayette MA +4 more
europepmc +2 more sources
RXR Gamma Enables Oligodendrocyte Differentiation by Suppressing Sonic Hedgehog Signaling. [PDF]
GliaUsing pharmacogenetic approaches, Baldassarro et al. demonstrate that RXRγ suppresses the SHH signaling pathway in OPCs to ensure their efficient differentiation following T3 stimulation. Accordingly, Rxrg−/− OPCs displayed compromised differentiation which was normalized by the pharmacological inhibition of the hyperactive SHH pathway.
Baldassarro VA +4 more
europepmc +2 more sources
Thyroid hormones correlate with field metabolic rate in ponies, Equus ferus caballus [PDF]
, 2016 Acknowledgments The authors thank Jürgen Dörl for technical help and for taking care of the animals and Peter Thompson for technical assistance with the doubly labelled water analysis.
Brinkmann, Lea +4 more
core +1 more source
Biomedicines, 2021 Ischemic heart disease is the main cause of death globally. Cardioprotection is the process whereby mechanisms that reduce myocardial damage, and activate protective factors, contribute to the preservation of the heart. Targeting these processes could be
Ozlem Ozen Karakus +7 more
doaj +1 more source
Triiodothyronine and free thyroxine levels are differentially associated with metabolic profile and adiposity-related cardiovascular risk markers in euthyroid middle-aged subjects [PDF]
, 2014 Background: We previously showed that in healthy young men a less favorable body composition is associated with higher FT3 levels within the euthyroid range.
De Buyzere, Marc +6 more
core +2 more sources
Iodine Deficiency and Learning Disabilities
Pediatric Neurology Briefs, 1996 The effect of prolonged iodine deficiency on learning and motivation to achieve was studied in 100 male children selected from both severely iodine-deficient (SID) and mildly iodine-deficient (MID) villages and reported from the Department of Psychology,
J Gordon Millichap
doaj +1 more source
Triiodothyronine (T3), inflammation and mortality risk in patients with acute myocardial infarction
European Thyroid Journal, 2023 Objectives: To study the relationship between serum-free T3 (FT3), C-reactive protein (CRP) and all-cause mortality in patients with acute myocardial infarction (AMI). Design: Prospective multicentre longitudinal cohort study.
Salman Razvi +10 more
doaj +1 more source
Radioimmunoassay of Triiodothyronine
Folia Endocrinologica Japonica, 1972 Immunization of rabbits with triiodothyronine-methyl ester hydrochloride conjugated to bovine serum albumin resulted in the production of antibody against triiodothyronine. Using dextran-coated charcoal technique, a practically useful and specific radioimmimoassay method for triiodothyronine was developed.
TOSHIRO SAKURADA +8 more
openaire +5 more sources
Thyroid thermogenesis in adult rat hepatocytes in primary monolayer culture: direct action of thyroid hormone in vitro. [PDF]
, 1979 We have studied the effect of 3,5,3'-triiodothyronine (T3) on the respiration of adult rat hepatocytes in primary monolayer culture prepared from hypothyroid rat liver. After addition of T3 to the culture medium at a concentration of 2 x 10(-7) M, oxygen
Bissell, DM +2 more
core +2 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source