Results 21 to 30 of about 46,293 (217)

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

open access: yesAdvanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun   +12 more
wiley   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

open access: yesAdvanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler   +4 more
wiley   +1 more source

Relative Potencies of Thyroxine and Triiodothyronine Based on Various Criteria in Thiouracil-Treated Chickens

open access: yes, 1957
Relative sensitivities of various criteria, which were found to be suitable qualitative indicators of thyroxine and triiodothyronine, were determined by calculating and comparing the amounts of each hormone necessary to maintain the control level of ...
W. S. Newcomer
core   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai   +2 more
wiley   +1 more source

Brown Adipose Tissue: An Extrathyroidal Source of Triiodothyronine

open access: yes, 1986
The role of brown adipose tissue in heat production is well known, but it is a novel concept that this tissue can activate the main secretory product of the thyroid gland, thyroxine, by converting it into the ten times more active triiodothyronine.
JE Silva
core   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz   +9 more
wiley   +1 more source

Phosphaturesis: a Direct Renal Effect of Triiodothyronine

open access: yes, 1958
A possible direct renal effect of thyroid hormone was investigated by administering 1.0 mg 3,5,3' l-triiodothyronine (T3) to normal dogs, and measuring the excretion of calcium, phosphorus, magnesium, creatinine and nitrogen for 4 1/2 hours thereafter ...
William B. Blythe   +3 more
core   +1 more source

Effect of Triiodothyronine in Different Dosages on Growth and Survival Rate of Giant Gouramy (Osphronemus gouramy Lac.) [PDF]

open access: yes, 2007
This experiment was conducted to study the effect of giant gouramy larval immersion in triiodothyronine (T3) hormone solution on their growth and survival rate. One-day old larvae were treated with different concentrations of triiodothyronine (T3) i.e. 0;
Carman, Odang   +5 more
core   +1 more source

Triiodothyronine Acts as a Smart Influencer on Hsp90 via a Triiodothyronine Binding Site [PDF]

open access: yes, 2022
Microarray-based experiments revealed that thyroid hormone triiodothyronine (T3) enhanced the binding of Cy5-labeled ATP on heat shock protein 90 (Hsp90).
Preller, Matthias   +9 more
core   +1 more source

Clinical, Radiologic and Cytologic Predictors of Malignancy in Pediatric Thyroid Nodules: Insights From a 26‐Year Cohort Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Introduction Thyroid nodules are less common but more often malignant in pediatric patients than in adults. Our objectives were to study the features of benign vs. malignant thyroid nodules in a large pediatric patient cohort. Methods Retrospective observational cohort study. Consecutive patients aged 0.01–17.9 years at evaluation between 1997–
Maxime Gest‐Laurent   +15 more
wiley   +1 more source

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