Results 31 to 40 of about 46,293 (217)

Triiodothyronine (T3) induces HIF1A and TGFA expression in MCF7 cells by activating PI3K

, 2016
High expression levels of hypoxia inducing factor 1 alpha are related to mammary carcinogenesis. In previous studies, we demonstrated that expression of transforming growth factor alpha increases upon treatment with triiodothyronine, but this expression ...
Moretto, Fernanda Cristina Fontes, Moretto, Fernanda Cristina Fontes [UNESP], Alves, Carlos Augusto Barnabe, Luvizon, Aline Carbonera, Nogueira, C�lia Regina [UNESP], Alves, Carlos Augusto Barnabe [UNESP], Nogueira, C�lia Regina, De Oliveira, Miriane, Conde, Sandro Jos� [UNESP], Olimpio, Regiane Marques Castro [UNESP], De Sibio, Maria Teresa, Conde, Sandro Jos�, Luvizon, Aline Carbonera [UNESP], De Oliveira, Miriane [UNESP], Olimpio, Regiane Marques Castro, De Sibio, Maria Teresa [UNESP]   +15 more
core   +1 more source

Triiodothyronine and Protein Malnutrition Could Influence Pulse Wave Velocity in Pre-Dialysis Chronic Kidney Disease Patients

, 2023
Cardiovascular diseases (CVD) are the first cause of chronic kidney disease (CKD) mortality. For personalized improved medicine, detecting correctable markers of CVD can be considered a priority.
Madalina Ticolea, Alina Potra, Andrada Barar, Ina Kacso, Maria Ticala, Ancuta M. Rotar, Cosmina Ioana Bondor, Diana Moldovan, Ana Valea, Remus Orasan, Crina Claudia Rusu, Cristian Budurea, Dacian Tirinescu, Florin Anton   +13 more
core   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source

Synaptosomal [125I]triiodothyronine after intravenous [125I]thyroxine.

, 1978
We administered [125I]thyroxine intravenously to adult male rats and measured uptake and subcellular distribution of the hormone and its metabolites in brain.
M B Dratman, F L Crutchfield
core   +1 more source

Incidence and Predictors of Immune‐Related Hypothyroidism Under Pembrolizumab Across Gynecologic Malignancies and Melanoma: A Real‐World Cohort Study

International Journal of Cancer, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) frequently cause thyroid immune‐related adverse events (irAEs). Permanent hypothyroidism, the clinically most relevant phenotype, requires lifelong hormone replacement. We investigated its incidence, course, risk factors, and prognostic relevance under pembrolizumab.
Freya Koffka, Johann Kornowski, Elena Laakmann, Barbara Schmalfeldt, Tim Zell, Glenn Geidel, Christoffer Gebhardt, Pia Roser, Volkmar Müller, Julian Kött   +9 more
wiley   +1 more source

Triiodothyronine stimulates cystatin C production in bone cells

, 2012
Thyroid hormones increase cystatin C levels in vivo. To study whether 3,3',5-triiodo-l-thyronine (T(3)) stimulates the production of cystatin C in vitro, we used a T(3)-responsive osteoblastic cell line (PyMS) which can be kept in serum-free culture.
Schmid, Christoph, Ghirlanda-Keller, Claudia, Zwimpfer, Cornelia, Zoidis, Evangelos, Schmid C, Ghirlanda-Keller C, Zoidis E, Zwimpfer C   +7 more
core   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Dose‐Dependent Efficacy of Radioiodine Therapy in Pediatric Graves’ Disease: A Retrospective Study of Hypothyroidism Risk and the Predictive Role of Thyroid Hormone Parameters

iRADIOLOGY, EarlyView.
RAI therapy demonstrated time‐dependent efficacy in pediatric Graves' disease, with gradually increasing treatment success and hypothyroidism incidence during follow‐up. Higher planned activity (≥ 0.15 mCi/g) was associated with a higher successful rate than lower planned activity (< 0.15 mCi/g), and LASSO analysis identified FT3 and TSH as candidate ...
Xiaoxue Tian, Dan Zhang, Yihui Wang, Lujie Cao, Junpu Jian, Jiangyan Liu, Changping Liang, Yinzhong Wang, Yonghui Chen   +8 more
wiley   +1 more source

Overview of the re‐evaluation of trace elements as nutritional feed additives in the European Union: characterization, safety, and efficacy

Journal of the Science of Food and Agriculture, EarlyView.
Abstract The re‐evaluation of feed additives in the European Union was outlined in the Regulation (EC) No 1831/2003. The primary objectives were to ensure safety and verify efficacy, as well as to update authorizations and phase out unsafe additives or those in which the industry expressed no interest.
Gloria López‐Gálvez, Maria de Lourdes Bastos, Francesco Cubadda, Mikolaj A Gralak, Christer Hogstrand, Matteo L Innocenti, Joop de Knecht, Marta López‐Alonso, Alberto Mantovani, Alena Pechová, Fernando Ramos, Jürgen Gropp   +11 more
wiley   +1 more source

The Effects of Cyclophosphamide on the Pharmacokinetics of Triiodothyronine in the Male Rat

, 1996
In the present study, the possibility that cyclophosphamide or a cyclophosphamide metabolite may be accelerating the clearance of triiodothyronine has been examined.
Lloyd N Sansom, Timothy C Smeaton, Ieva Stupans, Manya T Angley   +3 more
core   +1 more source