Results 31 to 40 of about 42,910 (268)
Biomedicines, 2022 Thyroid hormones have immunomodulatory roles, but their effects on the transcriptome and epigenome of innate immune cell types remain unexplored. In this study, we investigate the effects of triiodothyronine (T3) on the transcriptome and methylome of ...
Rebecca Shepherd +3 more
doaj +1 more source
Endocrine JournalWe and other investigators reported that mild TSH suppression with levothyroxine (LT4) was needed to achieve normal free triiodothyronine (FT3) levels and metabolic euthyroid state in athyreotic patients. Consequently, management methods based on thyroid
Mitsuru Ito +9 more
doaj +1 more source
Ribogospodarsʹka Nauka Ukraïni, 2017 Purpose. To establish during the spring and summer period the physiologically-biochemical response of fish to the effect of excessive anthropogenic contamination on the indicators of the maintenance of hormones and glucose in their blood plasma, and the ...
V. Martseniuk +3 more
doaj +1 more source
Endocrine Connections, 2021 Objectives: Compared with other thyroid markers, fewer studies have explored the associations between triiodothyronine (T3), T3/free thyroxine (fT4) and glucose abnormality during pregnancy.
Beibei Zhu +7 more
doaj +1 more source
In Vitro Responses of the Epidermis to Triiodothyronine
, 1978 The effect of exogenous triiodothyronine on replication and anabolic activity in human epidermis has been studied in vitro Measurements of epidermal replication, as estimated by a labeling index technique and by thymidine incorporation into skin sheets ...
Holt, Peter J A
core +1 more source
Advanced Healthcare Materials, EarlyView.Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim +5 more
wiley +1 more source
Frontiers in Endocrinology, 2019 The thyroid hormone triiodothyronine (T3) plays a fundamental role in growth regulation, differentiation, metabolism and cellular movement. These processes are particularly important considering that deregulation of T3 levels could promote abnormal ...
Ivonne Denise Uzair +4 more
doaj +1 more source
RXR Gamma Enables Oligodendrocyte Differentiation by Suppressing Sonic Hedgehog Signaling. [PDF]
GliaUsing pharmacogenetic approaches, Baldassarro et al. demonstrate that RXRγ suppresses the SHH signaling pathway in OPCs to ensure their efficient differentiation following T3 stimulation. Accordingly, Rxrg−/− OPCs displayed compromised differentiation which was normalized by the pharmacological inhibition of the hyperactive SHH pathway.
Baldassarro VA +4 more
europepmc +2 more sources
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Journal of Physical Fitness and Sports Medicine, 2022 Menstrual disorders are health problems in female athletes. It has also been reported that amenorrhea can lead to metabolic suppression. However, studies regarding resting energy expenditure (REE) in Japanese female athletes with menstrual disorders are ...
Kuniko Moto +4 more
doaj +1 more source