Results 31 to 40 of about 12,230 (281)

Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control

open access: yesScientific Reports, 2021
Obesity induces skeletal muscle dysfunction. The pathogenesis of which appears to substantially involve mitochondrial dysfunction, arising from impaired quality control. Exercise is a major therapeutic strategy against muscle dysfunction.
Wenliang Zhang   +9 more
doaj   +1 more source

Determination of trimetazidine in urine by capillary electrophoresis with amperometric detection

open access: yesChemical Monthly, 2023
In this contribution, nonaqueous capillary electrophoresis with end-column amperometric detection using a platinum ultramicroelectrode is presented along with several extraction procedures, both liquid–liquid extraction (LLE) and solid-phase extraction ...
Martin Baroch, H. Dejmková, F. Matysik
semanticscholar   +1 more source

Trimetazidine as a modifier of doxorubicin+cyclophosphamideinduced hyperdyslipidemia

open access: diamondThe Siberian Journal of Clinical and Experimental Medicine, 2022
Aim. The present work aimed at studying the proatherogenic potential of doxorubicin-cyclophosphamide (AC) chemotherapy regimen while simultaneously substantiating the use of trimetazidine as a modifier of the changes induced.Material and Methods.
Ashot Avagimyan, Lev Kakturskiy
openalex   +3 more sources

Use of a gene expression signature to identify trimetazidine for repurposing to treat bipolar depression

open access: yesBipolar Disorders, 2023
The aim of this study was to repurpose a drug for the treatment of bipolar depression.
C. Bortolasci   +29 more
semanticscholar   +1 more source

ACPTI study: Being positive in a negative situation is not naivety – Trimetazidine still has role in symptomatic CAD patients

open access: yesIndian Heart Journal, 2021
Results: of the efficAcy and safety of Trimetazidine in patients with angina pectoris having been treated by Percutaneous Coronary Intervention (ATPCI) study showed no significant difference in the incidence of primary endpoint events between ...
Jamshed Dalal, Aditya Kapoor
doaj   +1 more source

Trimetazidine Affects Mitochondrial Calcium Uniporter Expression to Restore Ischemic Heart Function via Reactive Oxygen Species/NFκB Pathway Inhibition

open access: yesJournal of Cardiovascular Pharmacology, 2023
Supplemental Digital Content is Available in the Text. Abstract: Studies have demonstrated the roles of trimetazidine beyond being an antianginal agent in ischemic heart disease (IHD) treatment associated with mechanisms of calcium regulation. Our recent
Zilong Xiao   +9 more
semanticscholar   +1 more source

Interest of hair tests to discriminate a tail end of a doping regimen from a possible contamination in case of challenging an anti-doping rule violation. V. Case reports involving trimetazidine, a drug where the concentration after a single 20 mg dose has been established. [PDF]

open access: yesDrug Test Anal
From ingestion to hair incorporation Abstract The identification of trimetazidine, a medicine used for treating stable angina pectoris and for preventing angina attacks, has been recently observed in doping cases involving high profile athletes from various countries over the world.
Kintz P, Ameline A, Gheddar L.
europepmc   +2 more sources

Metabolic reprogramming promotes myogenesis during aging [PDF]

open access: yes, 2019
Sarcopenia is the age-related progressive loss of skeletal muscle mass and strength finally leading to poor physical performance. Impaired myogenesis contributes to the pathogenesis of sarcopenia, while mitochondrial dysfunctions are thought to play a ...
Belli, R   +11 more
core   +3 more sources

Trimetazidine for stable angina [PDF]

open access: yesCochrane Database of Systematic Reviews, 2005
Patients with stable angina not controlled by monotherapy with nitrates, beta blockers, or calcium channel blockers are often treated with combinations of these drugs. There may be adverse effects from, or contraindications to, the use of combinations.
A, Ciapponi, R, Pizarro, J, Harrison
openaire   +2 more sources

Comparison of Cardioprotective Effects of Dapagliflozin and Trimetazidine in the Model of Doxorubicin-Cyclophosphamide Cardiotoxicity

open access: yesInnovative Medicine of Kuban, 2023
Background: Data published by task groups of the Ministry of Health of the Russian Federation, the European Society of Cardiology, and other medical associations and institutions show that chemotherapy-induced cardiomyopathy is still a challenging issue ...
©А.А. Авагимян   +27 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy