Results 161 to 170 of about 99,360 (296)

De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi, Alastair G. McEwan, Ulrike Kappler   +2 more
wiley   +1 more source

The Brief Case: <i>Cystoisospora belli</i> in the duodenal aspirate of an HIV-infected child. [PDF]

J Clin Microbiol
Tejan N, Bhatnagar N, Dinkar A, Singh S.
europepmc   +1 more source

Seasonal Restructuring of Microbial Communities and Resistomes in the Shitalakshya River, Bangladesh Revealed by Shotgun Metagenomics

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Dry‐season pollutant concentration drives microbial restructuring in Bangladesh's Shitalakshya River, shifting communities from Myroides to stress‐tolerant genera while enriching metal resistance genes and efflux pumps, revealing non‐antibiotic co‐selection as a key driver of antimicrobial resistance in urban waters.
Muhammad Ehteshamul Haque, Md. Shaminur Rahman, Munawar Sultana, Anowara Begum   +3 more
wiley   +1 more source

Veterinary fixed-dose antibiotics in Africa: a need for evidence-based regulation. [PDF]

Vet Res
Muloi DM, Kirimi H, Mwaura J, Ibayi EL, Moodley A.   +4 more
europepmc   +1 more source

One Health Insights From Pteropus medius: Nipah Virus Spillover, Microbiota, and Antimicrobial Resistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury, Shah Md Tanvir Khan, Sajal Roy, Md. Shohel Al Faruk   +3 more
wiley   +1 more source

Comparative evaluation of trimethoprim-sulfonamide ratios and synergistic interactions against porcine respiratory pathogens. [PDF]

Front Vet Sci
Mag P, Klein U, Depondt W, Piross IS, Tóth R, Somogyi Z, Kovács D, Kerek Á, Jerzsele Á.   +8 more
europepmc   +1 more source

Low-Dose Trimethoprim-Sulfamethoxazole Prophylaxis for Pneumocystis jirovecii Pneumonia in a Critically Ill Patient with HIV/TB Coinfection: Pharmacokinetics and Clinical Outcomes

Xiaoqing Ma, Ruoying Zhang, Ren Zheng, Junjie Cheng, Chongyang Wu, Xinjun Cai, Jinmeng Li Department of Pharmacy, Hangzhou Red Cross Hospital, Hangzhou, Zhejiang Province, 310000, People’s Republic of ChinaCorrespondence: Jinmeng Li, Department of ...
Li J, Ma X, Wu C, Zheng R, Zhang R, Cai X, Cheng J   +6 more
core   +1 more source

Metabolic reconstruction reveals ATP salvage as a key response to trimethoprim treatment. [PDF]

iScience
Carter C, Singh D, Wain J, Langridge GC.
europepmc   +1 more source

Empagliflozin Versus Dapagliflozin and Urogenital Adverse Events in Type 2 Diabetes: A Target Trial Emulation

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7367-7379, August 2026.
ABSTRACT Aims Urogenital adverse events are common with sodium‐glucose co‐transporter 2 inhibitors (SGLT2i) and may influence treatment decisions. Variations in SGLT2i selectivity, potency and effects on renal glucose excretion could lead to differences in safety profiles. We compared the risks of urinary tract infection (UTI), genital tract infection (
Christine Ljungberg, Kasper Bonnesen, Morten Schmidt, Christina Vandenbroucke‐Grauls, Michael Dalager‐Pedersen, Henrik Toft Sørensen, Mette Nørgaard, Reimar Wernich Thomsen   +7 more
wiley   +1 more source

Species distribution and antimicrobial resistance of <i>Staphylococcus</i> spp. isolated from dogs and cats in Poland: a retrospective laboratory-based study. [PDF]

Front Vet Sci
Tyc J, Jańczak D, Górecki P, Wójtowicz W, Hylińska K, Woźniakowski G.   +5 more
europepmc   +1 more source