Results 171 to 180 of about 123,230 (304)
A Review of Virtual Twins in Physiologically‐Based Pharmacokinetic Modeling and Simulation
The novel application of Virtual Twins (VT) in PBPK (VT‐PBPK) presents the opportunity to advance precision dosing and accelerate the shift from one‐size‐fits‐all to targeted, individualized treatments. This review aims to: (1) critically evaluate existing research on the use of VTs in PBPK, (2) develop a conceptual definition of VT‐PBPK, (3) describe ...
Emily Mannix +4 more
wiley +1 more source
Trimethoprim/Sulfamethoxazole-Induced Systemic Toxic Epidermal Necrolysis Syndrome: A Case Report. [PDF]
Wang Q, Chen L, Ye W.
europepmc +1 more source
Effects of Timing of Microbial Exposure on Microbiome Assembly and Amphibian Immune Development
We used a novel amphibian gnotobiotic system to investigate how disruptions to the microbiome during critical developmental periods influence microbial assembly and the development of immunity. We found that antimicrobial treatments of embryos and subsequent introduction to microbes at different developmental stages altered microbiome assembly ...
Abigail J. Miller +5 more
wiley +1 more source
Maternal, Fetal, and Neonatal Outcomes of Additional Dihydroartemisinin-Piperaquine to Trimethoprim-Sulfamethoxazole in Intermittent Preventive Treatment for Malaria in HIV-Positive Pregnancies: A Systematic Review and Meta-Analysis. [PDF]
Yunivita V +4 more
europepmc +1 more source
ABSTRACT Background and Aims Idiopathic Granulomatous Mastitis (IGM) is a rare, chronic inflammatory breast condition with uncertain etiology and challenging management. Standard treatments often involve corticosteroids or surgery, both associated with significant relapse and adverse effects.
Soheila Sayad +5 more
wiley +1 more source
ABSTRACT Background and Aims Methicillin‐resistant Staphylococcus aureus (MRSA) is a significant pathogen associated with hospital‐acquired infections, with its global prevalence, including in Indonesia, steadily increasing. However, comprehensive data on MRSA prevalence and antimicrobial susceptibility within Indonesian hospital settings remain ...
Muhammad Evy Prastiyanto +2 more
wiley +1 more source
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos +11 more
wiley +1 more source

