Results 71 to 80 of about 139,001 (302)
A Review of Virtual Twins in Physiologically‐Based Pharmacokinetic Modeling and Simulation
Clinical Pharmacology &Therapeutics, EarlyView.The novel application of Virtual Twins (VT) in PBPK (VT‐PBPK) presents the opportunity to advance precision dosing and accelerate the shift from one‐size‐fits‐all to targeted, individualized treatments. This review aims to: (1) critically evaluate existing research on the use of VTs in PBPK, (2) develop a conceptual definition of VT‐PBPK, (3) describe ...
Emily Mannix +4 more
wiley +1 more source
Trimethoprim-induced hyperkalemia in renal transplant recipient
Indian Journal of Transplantation, 2018 Trimethoprim-sulfamethoxazole (TMP-SMX) is an antimicrobial agent used in a variety of infections. Adverse reactions are more common in patients with AIDS but occasionally occur in immunocompetent patients.
Abhijeet S More +3 more
doaj +1 more source
Antibiotic sensitivities of urinary tract pathogenes in Maltese patients [PDF]
, 1993 A survey of over 1000 bacterial isolates from Maltese patients with urinary tract infection was performed in order to investigate resistance patterns to commonly used oral antibiotics.
Borg, Michael Angelo
core
Antibiotics in acute bronchitis: a meta-analysis. [PDF]
, 1999 PurposeMost patients with acute bronchitis who seek medical care are treated with antibiotics, although the effectiveness of this intervention is uncertain.
Bent, S +3 more
core +1 more source
Food Safety and Health, EarlyView.ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei +4 more
wiley +1 more source
MicroorganismsWe investigated whether the maximum residual levels of trimethoprim permitted in food (Acceptable Daily Intake—ADI) could select for de novo trimethoprim resistance in Escherichia coli in vivo. We designed chronic infection models of E.
Jaime Knox Macleod +5 more
doaj +1 more source
Genetic algorithm-based wavelength selection in multicomponent spectrophotometric determination by PLS: Application on sulfamethoxazole and trimethoprim mixture in bovine milk [PDF]
Journal of the Serbian Chemical Society, 2013 The simultaneous determination of sulfamethoxazole (SMX) and trimethoprim (TMP) mixtures in bovine milk by spectrophotometric method is a difficult problem in analytical chemistry, due to spectral interferences.
Givianrad Hadi Mohammad +2 more
doaj +1 more source
Social interactions in the Burkholderia cepacia complex : biofilms and quorum sensing [PDF]
, 2010 Burkholderia cepacia complex bacteria are opportunistic pathogens that cause respiratory tract infections in susceptible patients, mainly people with cystic fibrosis. There is convincing evidence that B.
Coenye, Tom
core +2 more sources
iMetaOmics, EarlyView.Genome surveillance across a swine‐associated One Health continuum in China shows that slaughterhouses act as major enrichment nodes for tet(X4)‐mediated tigecycline resistance, driven by putative clonal transmission and stable plasmid backbones. Integrating global datasets enables lineage‐specific risk stratification, highlighting key control points ...
Qin Wang +10 more
wiley +1 more source