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Trimethylamine N-Oxide and Risk of Cardiovascular Disease and Mortality
Current Nutrition Reports, 2018Trimethylamine N-oxide (TMAO) is a gut microbiota-dependent metabolite produced from choline and phosphatidylcholine. Trimethylamine N-oxide was found associated with enhanced atherosclerosis and thrombosis in vitro and in vivo. We summarized available clinical studies which investigated TMAO's role in predicting prognostic outcomes, including ...
Chanavuth, Kanitsoraphan +3 more
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Trimethylamine-N-oxide and its biological variations in vegetarians
European Journal of Nutrition, 2016Restriction of animal foods and choline may affect plasma trimethylamine-N-oxide (TMAO). In vegetarians, we investigated the association between TMAO concentrations and the strictness of the diet or sex. We also studied the biological variations of TMAO in vegans.Concentrations of plasma TMAO and choline metabolites were measured in 38 vegans and 67 ...
Obeid, Rima +3 more
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Gut Microbial Metabolite Trimethylamine N-Oxide Aggravates Pulmonary Hypertension
American Journal of Respiratory Cell and Molecular Biology, 2022Tao Wang, Haiyang Tang, Cheng Hong
exaly
Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction
Cell Metabolism, 2019Emily Balskus +2 more
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