Results 1 to 10 of about 1,333 (111)
Eurasian Journal of Medicine, 2023 Trimethylamine N-oxide (TMAO), the oxidized form of trimethylamine (TMA), was previously thought to be a waste product but is now considered an important risk factor for cardiovascular disease (CVD) and its comorbidities. Foods or supplements containing
Yasemin Karaagac
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Trimethylamine N-oxide in atrial fibrillation progression
International Journal of Cardiology: Heart & Vasculature, 2020 The human gut microbiome and its metabolite Trimethylamine N-oxide (TMAO) are sensitive to the human diet and are involved in the complex pathomechanisms that underpin diabetes, obesity, and cardiovascular diseases.
Petra Büttner +7 more
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Gut microbiota dependant trimethylamine N-oxide and hypertension
Frontiers in Physiology, 2023 The human gut microbiota environment is constantly changing and some specific changes influence the host’s metabolic, immune, and neuroendocrine functions.
Katongo H. Mutengo +6 more
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Trimethylamine N-Oxide: The Good, the Bad and the Unknown [PDF]
Toxins, 2016 Trimethylamine N-oxide (TMAO) is a small colorless amine oxide generated from choline, betaine, and carnitine by gut microbial metabolism. It accumulates in the tissue of marine animals in high concentrations and protects against the protein ...
Manuel T. Velasquez +3 more
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Role of Trimethylamine N-Oxide in Heart Failure
Reviews in Cardiovascular MedicineHeart failure (HF) is a clinical syndrome characterizing by typical physical signs and symptomatology resulting from reduced cardiac output and/or intracardiac pressure at rest or under stress due to structural and/or functional abnormalities of the ...
Lele Jing +6 more
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Targeting Trimethylamine N-Oxide: A New Therapeutic Strategy for Alleviating Atherosclerosis
Frontiers in Cardiovascular Medicine, 2022 Atherosclerosis (AS) is one of the most common cardiovascular diseases (CVDs), and there is currently no effective drug to reverse its pathogenesis. Trimethylamine N-oxide (TMAO) is a metabolite of the gut flora with the potential to act as a new risk ...
Lele Jing +6 more
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A Multi-Omic Association Study of Trimethylamine N-Oxide [PDF]
Cell Reports, 2018 Trimethylamine N-oxide (TMAO) is a circulating metabolite that has been implicated in the development of atherosclerosis and cardiovascular disease (CVD). In this paper, we identify blood markers, metabolites, proteins, gut microbiota patterns, and diets that are significantly associated with levels of plasma TMAO.
Matthew P Conomos +2 more
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Trimethylamine-N-oxide and cerebral stroke risk: A review
Neurobiology of DiseaseTrimethylamine-N-oxide (TMAO) is a gut microbiota-derived metabolite produced by the action of gut microbiota and the hepatic enzyme Flavin Mono‑oxygenase 3 (FMO3).
Phurbu Dolkar +13 more
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Trimethylamine N-oxide—a marker for atherosclerotic vascular disease [PDF]
Reviews in Cardiovascular Medicine, 2021 As a potential causative factor in various cardiovascular diseases, the gut microbe-generated metabolite trimethylamine N-oxide (TMAO) has courted considerable research interest as a potential biomarker.
Guinan Xie +4 more
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Trimethylamine N-oxide in cardiovascular disease
Advances in Clinical and Experimental Medicine, 2022 Although traditional cardiovascular risk factors are well established and understood, mortality and morbidity in patients with cardiovascular disease (CVD) remains high. Exploring new pathophysiological pathways enables a better understanding of CVD at both the molecular and clinical levels.
Radoslaw Konieczny, Wiktor Kuliczkowski
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