Results 41 to 50 of about 14,468,554 (196)

Molecular Engineering of a Mixed‐Spacer System Toward High‐Performance Polycarbazole Anion‐Exchange Membranes

open access: yesAngewandte Chemie, EarlyView.
Mixed‐spacer polycarbazole membranes balance conductivity, swelling, and stability by tuning hydration and ionic connectivity. The optimized membrane reaches 184 mS cm−1 hydroxide conductivity and 2.51 W cm−2 peak power density, offering a promising strategy for high‐performance ether‐free AEMs.
Hao Liu   +12 more
wiley   +2 more sources

Intestinal Microbiota Metabolism and Atherosclerosis

open access: yesChinese Medical Journal, 2015
Objective: This review aimed to summarize the relationship between intestinal microbiota metabolism and cardiovascular disease (CVD) and to propose a novel CVD therapeutic target.
Tian-Xing Liu   +2 more
doaj   +1 more source

TMAO metaorganismal pathway and chronic inflammatory diseases [PDF]

open access: yesExploration of Medicine
Nutrients containing a trimethylamine (TMA) moiety in their structure can be metabolized by the gut microbiota through enzymatic cleavage of the C-N bond, producing TMA.
Zeneng Wang, Shumei Man, Robert Koeth
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo   +9 more
wiley   +1 more source

Association between egg-derived phosphatidylcholine intake and trimethylamine N-oxide in healthy middle-aged and older adults

open access: yesLipids in Health and Disease
Background Egg-derived phosphatidylcholine may support the maintenance of cognitive function. However, its metabolite trimethylamine N-oxide is considered a potential cardiovascular risk factor.
Wei Wang   +6 more
doaj   +1 more source

Transient trimethylaminuria related to menstruation

open access: yesBMC Medical Genetics, 2007
Background Trimethylaminuria, or fish odor syndrome, includes a transient or mild malodor caused by an excessive amount of malodorous trimethylamine as a result of body secretions.
Yamazaki Hiroshi   +2 more
doaj   +1 more source

Structure‐Property Relationships in Catecholamine Coatings for Broad Surface Functionalization

open access: yesAdvanced Functional Materials, EarlyView.
Inspired by mussel adhesive proteins (MAPs), six catecholamine molecules with different molecular structure were systematically characterized and compared based on their ability to form homogeneous, reactive coatings. Highlighting candidates capable of balancing coating properties of interest, their successful use as primer layers for organic and ...
Caroline F. Harms   +5 more
wiley   +1 more source

Analysis of metabolomic patterns in thoroughbreds before and after exercise [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2017
Objective Evaluation of exercise effects in racehorses is important in horseracing industry and animal health care. In this study, we compared metabolic patterns between before and after exercise to screen metabolic biomarkers for exercise effects in ...
Hyun-Jun Jang   +8 more
doaj   +1 more source

Higher Trimethylamine-N-Oxide Plasma Levels with Increasing Age Are Mediated by Diet and Trimethylamine-Forming Bacteria

open access: yesmSystems, 2021
The gut microbiota-dependent metabolite trimethylamine-N-oxide (TMAO) is linked to an increased risk for cardiovascular diseases. Trimethylamine (TMA), which is subsequently oxidized to TMAO in the liver, is formed by intestinal bacteria via distinct ...
Silke Rath   +11 more
doaj   +1 more source

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