Results 61 to 70 of about 561,219 (291)

Higher Trimethylamine-N-Oxide Plasma Levels with Increasing Age Are Mediated by Diet and Trimethylamine-Forming Bacteria

mSystems, 2021
The gut microbiota-dependent metabolite trimethylamine-N-oxide (TMAO) is linked to an increased risk for cardiovascular diseases. Trimethylamine (TMA), which is subsequently oxidized to TMAO in the liver, is formed by intestinal bacteria via distinct ...
Silke Rath, Katharina Rox, Sven Kleine Bardenhorst, Ulf Schminke, Marcus Dörr, Julia Mayerle, Fabian Frost, Markus M. Lerch, André Karch, Mark Brönstrup, Dietmar H. Pieper, Marius Vital   +11 more
doaj   +1 more source

The gut microbiota derived metabolite trimethylamine N-oxide: Its important role in cancer and other diseases.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
An expanding body of research indicates a correlation between the gut microbiota and various diseases. Metabolites produced by the gut microbiota act as mediators between the gut microbiota and the host, interacting with multiple systems in the human ...
Yuhua Zhou, Yuwei Zhang, Shengkai Jin, Jing Lv, Menglu Li, Ninghan Feng   +5 more
semanticscholar   +1 more source

Gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice.

Blood, 2020
The diversity of human microbiome heralds the difference of impact that gut microbial metabolites exert on allogenic graft-versus-host disease (GVHD), even though short-chain fatty acids and indole were demonstrated to reduce its severity. In this study,
Kunpeng Wu, Yan Yuan, Huihui Yu, Xin Dai, Shu Wang, Zhengxu Sun, Fen Wang, He Fei, Qiwang Lin, Hua Jiang, Tong Chen   +10 more
semanticscholar   +1 more source

Gut microbes impact stroke severity via the trimethylamine-N-oxide pathway

Cell Host and Microbe, 2021
SUMMARY Clinical studies demonstrate associations between circulating levels of the gut microbiota derived metabolite trimethylamine-N-oxide (TMAO) and incident stroke risks. However, a causal role of gut microbes in stroke has not yet been demonstrated.
Weifei Zhu, Kymberleigh A. Romano, Lin Li, J. Buffa, Naseer Sangwan, P. Prakash, Aaron N Tittle, Xinmin S Li, Xiaoming Fu, C. Androjna, Anthony j. DiDonato, Kimberly Brinson, B. Trapp, M. Fischbach, F. Rey, A. Hajjar, J. DiDonato, S. Hazen   +17 more
semanticscholar   +1 more source

Vat Polymerization 3D Printing for Controlled Drug Release Applications

Advanced Materials Technologies, Volume 11, Issue 11, 5 June 2026.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari, O. Thompson Mefford, M. Aaron Vaughn   +2 more
wiley   +1 more source

Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome

npj Biofilms and Microbiomes, 2021
Trimethylamine- N -oxide (TMAO), a derivative from the gut microbiota metabolite trimethylamine (TMA), has been identified to be an independent risk factor for promoting atherosclerosis.
Xingxing Li, Chunyan Su, Zhibo Jiang, Yu-xin Yang, Yue Zhang, Mengxia Yang, Xiumin Zhang, Yu Du, Jin Zhang, Li Wang, Jiandong Jiang, B. Hong   +11 more
semanticscholar   +1 more source

On the Road to Accurate Biomarkers for Cardiometabolic Diseases by Integrating Precision and Gender Medicine Approaches [PDF]

, 2019
The need to facilitate the complex management of cardiometabolic diseases (CMD) has led to the detection of many biomarkers, however, there are no clear explanations of their role in the prevention, diagnosis or prognosis of these diseases.
Argano, Vincenzo, Balistreri, Carmela Rita, Giarratana, Rosa Maria, Lio, Domenico, Scola, Letizia, Torre, Salvatore   +5 more
core   +1 more source

Flexible Chemiresistive Chitosan‐Glycerol Sensors on Laser‐Induced Graphene Electrodes for Room‐Temperature Ammonia Detection

Advanced Materials Technologies, EarlyView.
Flexible Chitosan‐glycerol sensor integrated with porous laser‐induced graphene (LIG) electrodes enable room‐temperature chemiresistive detection of ammonia (NH3) and proof‐of‐concept detection of fish spoilage. ABSTRACT We report a metal‐free sensor platform combining laser induced graphene (LIG) electrodes with drop‐deposited, glycerol‐plasticized ...
Mintesinot Tamiru Mengistu, Richard Murray, Cara‐Lena Nies, Cathal Larrigy, Martina Piletti, Jahidul Islam, Daniela Iacopino, Eileen Hurley, Michael Nolan, Aidan J. Quinn   +9 more
wiley   +1 more source

Secondary aerosol formation from atmospheric reactions of aliphatic amines [PDF]

, 2007
Although aliphatic amines have been detected in both urban and rural atmospheric aerosols, little is known about the chemistry leading to particle formation or the potential aerosol yields from reactions of gas-phase amines.
Chhabra, P., Flagan, R. C., Knipping, E., Kroll, J. H., Murphy, S. M., Ng, N. L., Seinfeld, J. H., Sorooshian, A., Surratt, J. D., Tong, C.   +9 more
core   +3 more sources

Relationship between red meat metabolite trimethylamine N-oxide and cardiovascular disease

Heart and Mind, 2022
Many cardiovascular diseases (CVD) are caused by the interplay of lifestyle and genetic factors. Studies have suggested an association between red meat consumption and increased CVD risk. There is evidence indicating that trimethylamine N-oxide (TMAO), a
Angatu Yousuf, David G McVey, Shu Ye
doaj   +1 more source