Results 81 to 90 of about 561,219 (291)

Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction

Cellular Physiology and Biochemistry, 2017
Background/Aim: Plasma trimethylamine-N-oxide (TMAO), a product of intestinal microbial metabolism of dietary phosphatidylcholine has been recently associated with atherosclerosis and increased risk of cardiovascular diseases (CVD) in rodents and humans.
Krishna M. Boini, Tahir Hussain, Pin-Lan Li, Sai S Koka   +3 more
doaj   +1 more source

The Influence of Prebiotic Arabinoxylan Oligosaccharides on Microbiota Derived Uremic Retention Solutes in Patients with Chronic Kidney Disease: A Randomized Controlled Trial. [PDF]

PLoS ONE, 2016
UNLABELLED:The colonic microbial metabolism is a key contributor to uremic retention solutes accumulating in patients with CKD, relating to adverse outcomes and insulin resistance.
Ruben Poesen, Pieter Evenepoel, Henriette de Loor, Jan A Delcour, Christophe M Courtin, Dirk Kuypers, Patrick Augustijns, Kristin Verbeke, Björn Meijers   +8 more
doaj   +1 more source

Implication of Trimethylamine N-Oxide (TMAO) in Disease: Potential Biomarker or New Therapeutic Target

Nutrients, 2018
Trimethylamine N-oxide (TMAO) is a molecule generated from choline, betaine, and carnitine via gut microbial metabolism. The plasma level of TMAO is determined by several factors including diet, gut microbial flora, drug administration and liver flavin ...
M. H. Janeiro, M. J. Ramírez, F. Milagro, J. Martínez, M. Solas   +4 more
semanticscholar   +1 more source

Escherichia coli TatA and TatB Proteins Have N-out, C-in Topology in Intact Cells [PDF]

, 2012
The twin arginine protein transport (Tat) system translocates folded proteins across the cytoplasmic membrane of prokaryotes and the thylakoid membrane of chloroplasts.
Alami, Bartolomé, Bauer, Berks, Bernhardt, Berthelmann, Bogsch, Bolhuis, Bryson, Buchanan, Casadaban, Chan, Cline, Cline, Dabney-Smith, Dabney-Smith, de Leeuw, De Leeuw, Gohlke, Gouffi, Greene, Hashimoto-Gotoh, Heijne, Hu, Ize, Jack, Jack, Laemmli, Leake, Lee, Leive, Lu, Maegawa, Maldonado, Mori, Mori, Palmer, Palmer, Porcelli, Punginelli, Richter, Sambrook, Sargent, Sargent, Sargent, Sauvé, Silvestro, Simons, Stanley, Stevenson, Tarry, Tarry, Towbin, Walther, Wang, Weiner, Wessel, Wexler, Yen   +58 more
core   +3 more sources

Trimethylamine N-Oxide and Cardiovascular Events in Hemodialysis Patients [PDF]

Journal of the American Society of Nephrology, 2016
Cardiovascular disease causes over 50% of the deaths in dialysis patients, and the risk of death is higher in white than in black patients. The underlying mechanisms for these findings are unknown. We determined the association of the proatherogenic metabolite trimethylamine N-oxide (TMAO) with cardiovascular outcomes in hemodialysis patients and ...
Tariq, Shafi, Neil R, Powe, Timothy W, Meyer, Seungyoung, Hwang, Xin, Hai, Michal L, Melamed, Tanushree, Banerjee, Josef, Coresh, Thomas H, Hostetter   +8 more
openaire   +2 more sources

Trimethylamine N-Oxide and Related Metabolites in the Serum and Risk of Type 2 Diabetes in the Chinese Population: A Case-Control Study

Diabetes, Metabolic Syndrome and Obesity, 2023
Shenghong Qi,1,2 Lan Liu,1,2 Shulan He,1,2 Liqun Wang,1,2 Jiangping Li,1,2 Xian Sun1,2 1School of Public Health and Management, Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 2The Key Laboratory of Environmental Factors and ...
Qi S, Liu L, He S, Wang L, Li J, Sun X
doaj  

Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women

European Heart Journal, 2018
AIMS Carnitine and choline are major nutrient precursors for gut microbiota-dependent generation of the atherogenic metabolite, trimethylamine N-oxide (TMAO).
Zeneng Wang, N. Bergeron, B. Levison, Xinmin S Li, S. Chiu, Xun Jia, Robert A. Koeth, Lin Li, Yuping Wu, W. Tang, R. Krauss, S. Hazen   +11 more
semanticscholar   +1 more source

Relation between TMAOase activity and content of formaldehyde in fillet minces and bellyflap minces from gadoid fishes [PDF]

, 1997
Minced fish is a significant component of a number of frozen fishery products like fish fingers, cakes and patties. Predominately minced fish is produced from gadoid species (Alaska pollack, cod, saithe, hake and others) possessing the enzyme ...
Gonzales-Sotelo, C., Havemeister, W., Jessen, F., Jorgensen, B., Nielsen, M.K., Rehbein, Hartmut, Schubring, Reinhard   +6 more
core  

Prebiotic, Probiotic, and Synbiotic Supplementation in Chronic Kidney Disease: A Systematic Review and Meta-analysis [PDF]

, 2019
Gut dysbiosis has been implicated in the pathogenesis of chronic kidney disease (CKD). Restoring gut microbiota with prebiotic, probiotic, and synbiotic supplementation has emerged as a potential therapeutic intervention but has not been systematically ...
Campbell, Katrina L., Johnson, David W., McFarlane, Catherine, Ramos, Christiane I.   +3 more
core   +1 more source

Association between plasma trimethylamine N-oxide level and atrial fibrillation [PDF]

Jichu yixue yu linchuang
Objective To explore the relationship between plasma trimethylamine N-oxide(TMAO) level and atrial fibrillation(AF) by a clinical trial. Methods Totally 257 patients with AF were enrolled including 114 patients with paroxysmal AF and 143 with ...
YANG Wentao, ZHAO Qing, LI Xiangdong, WANG Yutang, LIU Wei
doaj   +1 more source