Results 91 to 100 of about 33,642 (251)

The N‐oxidation of trimethylamine in a Jordanian population. [PDF]

British Journal of Clinical Pharmacology, 1995
The ability to oxidise trimethylamine (TMA) to trimethylamine N‐oxide (TMAO) is distributed polymorphically within a British white population with the majority of individuals excreting greater than 90% of total urinary TMA as TMAO. The opposite extreme is characterised by a rare inborn error of TMA N‐oxidation known as the fish‐odour syndrome.
H F, Hadidi, S, Cholerton, S, Atkinson, Y M, Irshaid, N M, Rawashdeh, J R, Idle   +5 more
openaire   +2 more sources

Effect of Storage Temperature and Materials on Protein Quality and Functional Properties of Soybeans

Future Postharvest and Food, EarlyView.
Hermetic PICS bags combined with cool storage (15°C) effectively preserved soybean protein quality and functional properties ([protein solubility, emulsifying capacity, and oil absorption capacity] of soybean protein isolates) during storage. Polypropylene bags and 25°C accelerated protein deterioration lead to significant nutritional losses.
Rabia Msuya, Jamal Kussaga, Lucy Chove, Frederick Baijukya   +3 more
wiley   +1 more source

The food-derived metabolite trimethylamine and trimethylamine-N-oxide promote colorectal cancer progression via SREBF1

Ecotoxicology and Environmental Safety
Colorectal cancer (CRC) is characterised by microbial dysbiosis. Trimethylamine (TMA) and trimethylamine-N-oxide (TMAO) are gut microbiota-derived metabolites produced from dietary precursors that are implicated in CRC progression.
Yang Yan, Jiaxuan Li, Hejia Xu, Chen Yang, Guifang Li, Yanyan Feng, Qian Wang, Li Li, Rendi Wu, Hairong Sun, Ting Zhang, Fang Wang, Yong Mao   +12 more
doaj   +1 more source

The Role of Microbiota in Cardiovascular Risk: Focus on Trimethylamine Oxide [PDF]

, 2019
The extensive collection of bacteria cohabiting within the host collaborates with human functions and metabolisms in both health and disease. The fine equilibrium of commensals is tightly controlled and an imbalance (“dysbiosis”) in the gut microbiota ...
Al-Rubaye, H, Kaski, J-C, Perfetti, G
core   +1 more source

Trimethylamine-N-Oxide

JACC: Basic to Translational Science, 2021
Fadi W. Adel, Horng H. Chen
openaire   +1 more source

Urolithin A, a Diet‐Derived Gut Microbial Metabolite Against Pulmonary Hypertension Identified via Molecular Docking, Molecular Dynamics and Surface Plasmon Resonance

Food Safety and Health, EarlyView.
Urolithin A, a gut microbial metabolite, binds TNF to suppress proliferation, inflammation, and oxidative stress, offering a promising microbe‐derived therapeutic avenue for pulmonary hypertension. ABSTRACT Pulmonary hypertension (PH) is a complex and multifactorial disease that poses a significant clinical challenge.
Yujie Qu, Yinghua Huo, Yichen Wang, Yao Mu, Xue Yu, Leiyu Tian, Jian Guo, Xuezhi Yang, Yucai Chen   +8 more
wiley   +1 more source

Second‐trimester multimetabolite panel for early preeclampsia rule‐out

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective We aimed to establish a high‐sensitivity, multimetabolite rule‐out model for the development of preeclampsia (PE), prioritizing minimizing false negatives to exclude low‐risk individuals from intensive surveillance confidently. Methods In this prospective, nested case–control study, maternal serum samples were collected between 20+0 ...
Matthews Silva Martins, Julyane N. S. Kaihara, Diego Fortes Salgueiro, Viviane Cunha Cardoso, Silvana Maria Quintana, Ricardo Carvalho Cavalli, Valerio Garrone Barauna, Valeria Cristina Sandrim   +7 more
wiley   +1 more source

Trimethylamine N‐Oxide and Mortality Risk in Patients With Peripheral Artery Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundProduction of the proatherogenic metabolite, trimethylamine N‐oxide (TMAO), from dietary nutrients by intestinal microbiota enhances atherosclerosis development in animal models and is associated with atherosclerotic coronary artery disease in ...
Vichai Senthong, Zeneng Wang, Yiying Fan, Yuping Wu, Stanley L. Hazen, W. H. Wilson Tang   +5 more
doaj   +1 more source

Circulating metabolites from the choline pathway and acute coronary syndromes in a Chinese case-control study

Nutrition & Metabolism, 2020
Background Accumulating evidence shows that circulating levels of trimethylamine N-oxide, which is generated from the metabolism of dietary choline, may predict cardiovascular disease among Caucasians.
Yuxiang Dai, Qianqian Tian, Jing Si, Zhonghan Sun, Shalaimaiti Shali, Lili Xu, Daoyuan Ren, Shufu Chang, Xin Dong, Hongxia Zhao, Zhendong Mei, Yan Zheng, Junbo Ge   +12 more
doaj   +1 more source

Trimethylamine-N-oxide (TMAO) as novel potential biomarker of early predictors of metabolic syndrome [PDF]

, 2018
There is a mechanistic link between the gut-derived metabolite trimethylamine-N-oxide (TMAO) and obesity-related diseases, suggesting that the TMAO pathway may also be linked to the pathogenesis of obesity.
Annunziata, Giuseppe, Barrea, Luigi, Colao, Annamaria, de Alteriis, Giulia, Di Somma, Carolina, Laudisio, Daniela, Maisto, Maria, Muscogiuri, Giovanna, Savastano, Silvia, Tenore, Gian Carlo   +9 more
core   +2 more sources