Results 21 to 30 of about 14,468,554 (196)
Dose–response associations between (trimethylamine-N-oxide) TMAO and AIS risk.
, 2023 Dose–response associations between (trimethylamine-N-oxide) TMAO and AIS risk.
Nianqiu Liu (17290684) +7 more
core +1 more source
Trimethylamine-N-oxide: a potential biomarker and therapeutic target in ischemic stroke
Frontiers in Neurology, 2023 Ischemic stroke is by far the most common cerebrovascular disease and a major burden to the global economy and public health. Trimethylamine-N-oxide (TMAO), a small molecule compound produced by the metabolism of intestinal microorganisms, is reportedly ...
Yuan Liu +6 more
doaj +1 more source
Impact of trimethylamine-N-oxide (TMAO) plasma levels and acute ischemic stroke (AIS) risk.
, 2023 Impact of trimethylamine-N-oxide (TMAO) plasma levels and acute ischemic stroke (AIS) risk.
Nianqiu Liu (17290684) +7 more
core +1 more source
The biosynthesis of trimethylamine-N-oxide
Biochimica et Biophysica Acta, 1960 Norris and Benoit (1) provided ‘good evidence that injected trimethylamine is converted in the rat to its N-oxide and excreted in the urine. Other mammals have been shown to have the ability to effect the same reaction (2, 3). In a preliminary communication (4), we have reported that hog liver microsomes will catalyze the oxidation of trimethylamine in
J, BAKER, S, CHAYKIN
openaire +3 more sources
Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota [PDF]
, 2014 Dietary intake of L-carnitine can promote cardiovascular diseases in humans through microbial production of trimethylamine (TMA) and its subsequent oxidation to trimethylamine N-oxide (TMAO) by hepatic flavin-containing monooxygenases.
Schäfer, Hendrik +13 more
core +1 more source
Electronic fluctuation in physiological solutions: Trimethylamine N-oxide and tert-butyl alcohol [PDF]
, 2022 Although small organic molecules in cells have been considered important to control the functions of proteins, their electronic fluctuation under real physiological conditions has never been clarified due to the lack of observations.
Hirotoshi, Mori +7 more
core +2 more sources
Zinc Protoporphyrin–trimethylamine-N-Oxide Complex Involves Cholesterol Oxidation Causing Atherosclerosis [PDF]
, 2020 Trimethylamine-N-oxide (TMAO) has recently been correlated as biomarker for atherosclerosis. In a model study, we show that the free TMAO when bonded with zincprotoporphyrin IX, [ZnPP], in blood plasma as [TMAOZnPP] is transported to the lipid site is ...
Rudra, Sarkar +2 more
core +1 more source
Trimethylamine N-oxide (TMAO) in human health
EXCLI journal, 2021 Due to numerous links between trimethylamine-N-oxide (TMAO) and various disorders and diseases, this topic is very popular and is often taken up by researchers. TMAO is a low molecular weight compound that belongs to the class of amine oxides. It is formed by the process of oxidation of trimethylamine (TMA) by the hepatic flavin monooxygenases (FMO1 ...
Gatarek, Paulina +1 more
openaire +2 more sources
Trimethylamine-N-Oxide and Heart Failure
Journal of the American College of Cardiology, 2015 The new study by Tang et al. [(1)][1] demonstrating an inverse correlation of serum levels of trimethylamine- N -oxide (TMAO) with survival in patients with heart failure (HF) is intriguing and thought provoking. Similar findings have been published recently by Norwegian researchers.
McCarty, Mark F. +1 more
openaire +2 more sources
JACC: Basic to Translational Science, 2021 [Figure: see text]
Adel, Fadi W., Chen, Horng H.
openaire +2 more sources