Results 11 to 20 of about 561,219 (291)

The microbial metabolite trimethylamine N-oxide and the kidney diseases [PDF]

Frontiers in Cellular and Infection Microbiology
Trimethylamine N-oxide (TMAO), a metabolite, is a co-metabolite produced by both gut microbiota and livers, originating from foods rich in choline or carnitine.
Jin-Qi Su, Jin-Qi Su, Xiang-Qi Wu, Xiang-Qi Wu, Qi Wang, Qi Wang, Bo-Yang Xie, Bo-Yang Xie, Cui-Yan Xiao, Cui-Yan Xiao, Hong-Yong Su, Hong-Yong Su, Ji-Xin Tang, Ji-Xin Tang, Cui-Wei Yao, Cui-Wei Yao   +15 more
doaj   +4 more sources

Trimethylamine N-Oxide as a Potential Biomarker for Cardiovascular Disease: Its Association with Dietary Sources of Trimethylamine N-Oxide and Microbiota

Eurasian Journal of Medicine, 2023
Trimethylamine N-oxide (TMAO), the oxidized form of trimethylamine (TMA), was previously thought to be a waste product but is now considered an important risk factor for cardiovascular disease (CVD) and its comorbidities. Foods or supplements containing
Yasemin Karaagac
doaj   +3 more sources

Trimethylamine N-oxide in atrial fibrillation progression

International Journal of Cardiology: Heart & Vasculature, 2020
The human gut microbiome and its metabolite Trimethylamine N-oxide (TMAO) are sensitive to the human diet and are involved in the complex pathomechanisms that underpin diabetes, obesity, and cardiovascular diseases.
Petra Büttner, Jürgen G. Okun, Jana Hauke, Erik Holzwirth, Danilo Obradovic, Gerhard Hindricks, Holger Thiele, Jelena Kornej   +7 more
doaj   +3 more sources

Gut microbiota dependant trimethylamine N-oxide and hypertension

Frontiers in Physiology, 2023
The human gut microbiota environment is constantly changing and some specific changes influence the host’s metabolic, immune, and neuroendocrine functions.
Katongo H. Mutengo, Katongo H. Mutengo, Sepiso K. Masenga, Sepiso K. Masenga, Aggrey Mweemba, Wilbroad Mutale, Annet Kirabo   +6 more
doaj   +3 more sources

Trimethylamine N-oxide—a marker for atherosclerotic vascular disease [PDF]

Reviews in Cardiovascular Medicine, 2021
As a potential causative factor in various cardiovascular diseases, the gut microbe-generated metabolite trimethylamine N-oxide (TMAO) has courted considerable research interest as a potential biomarker.
Guinan Xie, An Yan, Peng Lin, Yi Wang, Liping Guo   +4 more
doaj   +3 more sources

Trimethylamine N-Oxide: The Good, the Bad and the Unknown [PDF]

Toxins, 2016
Trimethylamine N-oxide (TMAO) is a small colorless amine oxide generated from choline, betaine, and carnitine by gut microbial metabolism. It accumulates in the tissue of marine animals in high concentrations and protects against the protein ...
Manuel T. Velasquez, Ali Ramezani, Alotaibi Manal, Dominic S. Raj   +3 more
doaj   +3 more sources

Role of Trimethylamine N-Oxide in Heart Failure

Reviews in Cardiovascular Medicine
Heart failure (HF) is a clinical syndrome characterizing by typical physical signs and symptomatology resulting from reduced cardiac output and/or intracardiac pressure at rest or under stress due to structural and/or functional abnormalities of the ...
Lele Jing, Honghong Zhang, Qiannan Xiang, Huilin Hu, Changlin Zhai, Suining Xu, Hongen Tian   +6 more
doaj   +3 more sources

Plasma trimethylamine N-oxide (TMAO): associations with cognition, neuroimaging, and dementia

Alzheimer’s Research & Therapy
Background The gut-derived metabolite Trimethylamine N-oxide (TMAO) and its precursors - betaine, carnitine, choline, and deoxycarnitine – have been associated with an increased risk of cardiovascular disease, but their relation to cognition ...
Amber Yaqub, Dina Vojinovic, Meike W. Vernooij, P. Eline Slagboom, Mohsen Ghanbari, Marian Beekman, Jeroen van der Grond, Thomas Hankemeier, Cornelia M. van Duijn, M. Arfan Ikram, Shahzad Ahmad   +10 more
doaj   +2 more sources

Trimethylamine N-oxide in cardiovascular disease

Advances in Clinical and Experimental Medicine, 2022
Although traditional cardiovascular risk factors are well established and understood, mortality and morbidity in patients with cardiovascular disease (CVD) remains high. Exploring new pathophysiological pathways enables a better understanding of CVD at both the molecular and clinical levels.
Radoslaw Konieczny, Wiktor Kuliczkowski
openaire   +2 more sources

Atherosclerosis and trimethylamine-N-oxide — the gut microbiota potential

Российский кардиологический журнал, 2022
Gut dysbiosis contribute to the development of atherosclerosis. Firmicutes contain a trimethylamine-producing gene cluster. The aim was to analyze potential role of trimethylamine-N-oxide (TMAO), gut microbiota metabolite, in the pathogenesis of ...
I. N. Grigorieva
doaj   +1 more source