Results 161 to 170 of about 553,444 (284)

The roles of CymA in support of the respiratory flexibility of Shewanella oneidensisMR-1 [PDF]

open access: yes, 2012
Akagawamatsushita   +41 more
core   +1 more source

Too close for comfort: Self‐crowding transforms protein structure and stability beyond volume exclusion

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Proteins operate in crowded physiological environments, yet their conformational and oligomeric states are largely inferred from experiments performed under dilute buffer conditions. Here, we show that for lysozyme (LYS) and bovine serum albumin (BSA), self‐crowding at physiologically relevant concentrations alters protein structure and ...
Gil I. Olgenblum   +2 more
wiley   +1 more source

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen   +7 more
wiley   +1 more source

Gut Microbiota-Dependent Trimethylamine N-Oxide (TMAO) Pathway Contributes to Both Development of Renal Insufficiency and Mortality Risk in Chronic Kidney Disease

open access: yesCirculation Research, 2015
W. Tang   +8 more
semanticscholar   +1 more source

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1136-1140, May 2026.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Relation between TMAOase activity and content of formaldehyde in fillet minces and bellyflap minces from gadoid fishes [PDF]

open access: yes, 1997
Minced fish is a significant component of a number of frozen fishery products like fish fingers, cakes and patties. Predominately minced fish is produced from gadoid species (Alaska pollack, cod, saithe, hake and others) possessing the enzyme ...
Gonzales-Sotelo, C.   +6 more
core  

Trimethylamine-N-oxide reduction by alteromonas spp.

open access: yes, 1982
Trimethylamine-N-oxide (TMAO) is a nitrogenous compound widely distributed in marine fish and invertebrates. It has long been known that TMAO is reduced by bacteria during the post mortem spoilage of iced marine fish, but the mechanism involved and the physiological role have remained unknown.
openaire   +2 more sources

Gut Dysbiosis as a Shared Mechanism in Obesity and Hypertension: Exploring a Promising Therapeutic Avenue

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 3, May 2026.
This review synthesises current knowledge on gut microbiome involvement in obesity and hypertension, evaluates microbiome‐based therapeutic strategies, and identifies critical research gaps to guide future investigations aimed at mitigating the dual pandemics.
Andrej Belančić   +7 more
wiley   +1 more source

High‐Adhesion Quadruple Hydrogen‐Bonded Ionogels: A Dual‐Function Platform for Gesture Recognition and Real‐Time NH3 Detection in Multiscenario

open access: yesENERGY &ENVIRONMENTAL MATERIALS, Volume 9, Issue 3, May 2026.
Quadruple hydrogen‐bonded high‐adhesion ionogels for gesture recognition and real‐time NH3 sensing. Ionogels have garnered significant attention in flexible sensing due to their outstanding mechanical properties, conductivity, and stability. However, establishing a robust and stable adhesive interface with various substrates remains a significant ...
Haohao Lin   +7 more
wiley   +1 more source

Membrane Engineering for Battery Systems: Bridging Design Principles and Frontier Applications

open access: yesENERGY &ENVIRONMENTAL MATERIALS, Volume 9, Issue 3, May 2026.
The review emphasizes membrane separators' role in battery performance and safety, covering redox flow, lithium‐ion, and solid‐state batteries. It reviews advances in membrane materials (e.g., polymer electrolytes, hybrid composites) and ion transport mechanisms, while addressing challenges like dendrite growth and crossover losses.
Xiaoqun Zhou   +3 more
wiley   +1 more source

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