Results 181 to 190 of about 17,902 (222)

The role of trimethylamine N-oxide in disease pathogenesis and the therapeutic potential of traditional Chinese medicine. [PDF]

Front Pharmacol
Qin Z, Wu W, Yang X, Wang X, Ding A, Huang Y, Tang J, Jiang S, Zhang P, Qian C, Zhang X, Zhou S, Wang Y, Song Z, Sun M, Wang M, Shen S, Zhu B.   +17 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Genetic polymorphism of trimethylamine N-oxidation

Pharmacology & Therapeutics, 1990
Example of a food idiosyncracy, known to represent a pharmacogenetic polymorphism: trimethylaminuria of «fish-odour syndrome». Primary trimethylaminuria must be distinguished from the trimethylaminurias which are non-genetic in origin and which are secondary to other factors such as renal or hepatic disease or overload with trimethylamine ...
R, Ayesh, R L, Smith
openaire   +2 more sources

Trimethylamine-N-oxide Biosynthesis in the Bullfrog

Nature, 1966
THE comparative aspects of the mechanism of oxygenations dependent on molecular oxygen have recently been investigated using the biosynthesis of trimethylamine-N-oxide as a model1. That investigation raised a number of questions beyond the presence of the enzymatic activity in a given organism.
K, Murray, K, Chakraverty, S, Chaykin
openaire   +2 more sources

Trimethylamine N-Oxide (TMAO) as a Biomarker

2022
The interaction between diet, microbiome, and noncommunicable disease onset is gaining growing attention. The trimethylamine N-oxide (TMAO) is a gut microbiota derivative that has been suggested as a potential regulator of human health, especially (but not exclusively) for its association with cardiovascular diseases. It derives from the trimethylamine
Gabbianelli, Rosita, Bordoni, Laura
openaire   +3 more sources

Trimethylamine N-Oxide (TMAO), Diet and Cardiovascular Disease

Current Atherosclerosis Reports, 2021
The association between plasma Trimethylamine N-Oxide (TMAO), diet and risk for cardiovascular disease (CVD) is still not fully understood. While epidemiologic research shows a causal relationship between plasma TMAO concentrations and CVD risk, the role of dietary precursors in determining plasma concentrations of TMAO and biomarkers for CVD is ...
Minu S. Thomas, Maria Luz Fernandez
openaire   +2 more sources

A comparative study of trimethylamine-N-oxide biosynthesis

Biochimica et Biophysica Acta, 1963
A broad spectrum of species of plants and animals have been examined for their ability to convert trimethylamine to its N-oxide. Of the animal species studied, and under the conditions used in this investigation, trimethylamine-N-oxide synthesis from trimethylamine seems generally to be restricted to the vertebrates.
J R, BAKER, A, STRUEMPLER, S, CHAYKIN
openaire   +2 more sources

The role of trimethylamine‐N‐Oxide in the development of Alzheimer's disease

Journal of Cellular Physiology, 2021
AbstractAlzheimer's disease is associated with multiple risk factors and is the most common type of dementia. Trimethylamine‐N‐oxide (TMAO), a gut microbiota metabolite derived from dietary choline and carnitine, has recently been identified as a potential risk factor of Alzheimer's disease.
Nida Buawangpong, Kanokporn Pinyopornpanish, Natthapat Siri‐Angkul, Nipon Chattipakorn, Siriporn C. Chattipakorn   +4 more
openaire   +2 more sources

Microbial Dimethylsulfoxide and Trimethylamine-N-Oxide Respiration

2005
Over the last two decades, the biochemistry and genetics of dimethylsulfoxide (DMSO) and trimethylamine-N-oxide (TMAO) respiration has been characterised, particularly in Escherichia coli marine bacteria of the genus Shewanella and the purple phototrophic bacteria, Rhodobacter sphaeroides and R. capsulatus.
McCrindle, S. L., Kappler, U., McEwan, A. G.   +2 more
openaire   +5 more sources

Trimethylamine N-oxide synthesis: A human variant

Biochemical Medicine, 1972
Abstract A 6-year-old girl exhibiting a variety of clinical symptoms including an apparant inability to metabolize trimethylamine has been shown to possess a defective liver trimethylamine oxidizing system. The defect manifested itself in a Km for trimethylamine which was five times that characteristic of normal enzyme preparation.
T, Higgins, S, Chaykin, K B, Hammond, J R, Humbert   +3 more
openaire   +2 more sources