Results 181 to 190 of about 553,444 (284)

Comorbid Alzheimer's Disease and Type 2 Diabetes Microbiota Shape Age‐Associated Gut–Brain Axis Profiles

Aging Cell, Volume 25, Issue 5, May 2026.
Fecal microbiota transplantation from elderly donors with Alzheimer's disease, type 2 diabetes, or both conditions into antibiotic‐treated mice revealed that comorbid microbiota produce the most severe dysbiosis and strongest suppression of hippocampal neurotrophic gene expression.
Alessandro Atzeni, Jonas Mingaila, Gediminas Alzbutas, Rokas Lukoševičius, Justinas Drūteika, Kamila Łuczyńska, Rima Ramonaitė, Tadeusz Pietras, Kasper Sipowicz, Dovilė Kiudelytė, Karolina Keršytė, Emilija Keževičiūtė, Greta Najūtė, Juozas Kupčinskas, Jordi Mayneris‐Perxachs, Daiva Baltriukienė, Aurelijus Burokas   +16 more
wiley   +1 more source

Sodium butyrate ameliorates renal tubular lipid accumulation through a protein phosphatase 2A/transcription factor EB axis in diabetic nephropathy

British Journal of Pharmacology, Volume 183, Issue 9, Page 1901-1919, May 2026.
Abstract Background and Purpose Extensive evidence indicates that lipid accumulation causes renal tubular injury, which further contributes to diabetic nephropathy (DN) progression. Short‐chain fatty acids (SCFAs) play an important role in the maintenance of cellular metabolic health.
Jiayin Tao, Sinan Ai, Yaoxian Wang, Yuning Liu, Jingwei Zhou, Qingqing Liu, Xu Wang, Danting Li, Xin Li, Lin Wang, Jinyi Hou, Liang Peng, Zhen Wang   +12 more
wiley   +1 more source

Structure–Property Relationships in Fluorine‐Free Ionic Liquids and Salts Utilising the Acesulfame Anion

ChemSusChem, Volume 19, Issue 8, 28 April 2026.
Fluorine‐free acesulfame‐based ionic liquids and salts were synthesized and comprehensively analysed, revealing how anionic structure governs key physicochemical properties, paving the way towards safer and more sustainable electrolytes for clean energy storage.
Wern Huay Mah, Craig M. Forsyth, Luke A. O’Dell, Jennifer M. Pringle   +3 more
wiley   +1 more source

Enantioselectivity in Transition Metal Catalyzed Propargylic Substitution Reactions: A Theoretical Perspective

Chemistry – A European Journal, Volume 32, Issue 15, 22 April 2026.
Recent theoretical efforts to elucidate the origin of enantioselectivity in transition metal‐catalyzed propargylic substitution reactions are highlighted in this review. ABSTRACT In recent years, asymmetric catalytic propargylic substitution reactions have undergone remarkable development, enabling the construction of chiral carbon centers adjacent to ...
Ken Sakata, Yoshiaki Nishibayashi
wiley   +1 more source

Synthesis of Sulfur Heterocycles by Palladium‐Catalyzed Cyclization

European Journal of Organic Chemistry, Volume 29, Issue 14, 15 April 2026.
In spite of the well‐known palladium thiophilicity, sulfur‐containing acyclic substrates may efficiently undergo several different kinds of palladium‐catalyzed cyclization processes leading to highly important sulfur heterocycles in one synthetic step. Advances in this challenging and stimulating field of research are presented in this review.
Bartolo Gabriele
wiley   +1 more source

Chronic diseases associated with meat consumption : epidemiology and mechanisms [PDF]

, 2019
De Smet, Stefaan, Demeyer, Daniël, Van Hecke, Thomas   +2 more
core   +2 more sources

Alteration of gut microbiota contributes to peritoneal fibrosis through increased production of trimethylamine N-oxide. [PDF]

Gut Microbes
Xie W, Yuan J, Feng C, Shi H, Zhang C, Xi T, Huang J, Fang W, Ni Z, Gu L, Jiang N.   +10 more
europepmc   +1 more source

Involvement of trimethylamine N-oxide in major depressive disorder via astrocytic d-Serine dysregulation. [PDF]

Neurotherapeutics
Lin L, Li L, Ren S, Liu L, Liu Y, Zhang W, Gao Z, Ni X, Li H, Duan X, Tao S, Zhao T, Hai X.   +12 more
europepmc   +1 more source

Gut-Derived Metabolites and Cognitive Health: Roles of Short-Chain Fatty Acids and Trimethylamine N-oxide. [PDF]

Cureus
Gupta DK, Kumar R.
europepmc   +1 more source

Trimethylamine N-oxide is associated with long-term mortality risk: the multi-ethnic study of atherosclerosis.

European Heart Journal, 2023
Meng Wang, Xinmin S. Li, Zeneng Wang, Marcia C. de Oliveira Otto, R. Lemaitre, A. Fretts, N. Sotoodehnia, M. Budoff, I. Nemet, J. DiDonato, W. H. W. Tang, B. Psaty, D. Siscovick, S. Hazen, D. Mozaffarian   +14 more
semanticscholar   +1 more source