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Gut microbiota-derived metabolite trimethylamine N-oxide alters the host epigenome through inhibition of S-adenosylhomocysteine hydrolase. [PDF]
Han JH, Rey FE, Denu JM.
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Salivary trimethylamine N-oxide: a novel non-invasive marker for periodontal inflammation. [PDF]
Serdar CC +5 more
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Mechanisms and Intervention Strategies of Trimethylamine N-Oxide in Abdominal Aortic Aneurysm.
Abudureheman D +5 more
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Trimethylamine N-oxide (TMAO) in human health
Due to numerous links between trimethylamine-N-oxide (TMAO) and various disorders and diseases, this topic is very popular and is often taken up by researchers. TMAO is a low molecular weight compound that belongs to the class of amine oxides.
Paulina Gątarek +1 more
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Trimethylamine N-Oxide in Aquatic Foods.
Journal of Agricultural and Food ChemistryTrimethylamine N-oxide (TMAO), a characteristic nonprotein nitrogen compound, is widely present in seafood, which exhibits osmoregulatory effects for marine organisms in vivo and plays an important role in aquaculture and aquatic product preservation ...
Xiaoyue Li +5 more
semanticscholar +3 more sources
Trimethylamine N-Oxide (TMAO), Diet and Cardiovascular Disease
Current Atherosclerosis Reports, 2021The association between plasma Trimethylamine N-Oxide (TMAO), diet and risk for cardiovascular disease (CVD) is still not fully understood. While epidemiologic research shows a causal relationship between plasma TMAO concentrations and CVD risk, the role of dietary precursors in determining plasma concentrations of TMAO and biomarkers for CVD is ...
M. Thomas, M. Fernández
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Genetic polymorphism of trimethylamine N-oxidation
Pharmacology & Therapeutics, 1990Example of a food idiosyncracy, known to represent a pharmacogenetic polymorphism: trimethylaminuria of «fish-odour syndrome». Primary trimethylaminuria must be distinguished from the trimethylaminurias which are non-genetic in origin and which are secondary to other factors such as renal or hepatic disease or overload with trimethylamine ...
R, Ayesh, R L, Smith
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Trimethylamine-N-oxide Biosynthesis in the Bullfrog
Nature, 1966THE comparative aspects of the mechanism of oxygenations dependent on molecular oxygen have recently been investigated using the biosynthesis of trimethylamine-N-oxide as a model1. That investigation raised a number of questions beyond the presence of the enzymatic activity in a given organism.
K, Murray, K, Chakraverty, S, Chaykin
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Trimethylamine N-oxide synthesis: A human variant
Biochemical Medicine, 1972Abstract A 6-year-old girl exhibiting a variety of clinical symptoms including an apparant inability to metabolize trimethylamine has been shown to possess a defective liver trimethylamine oxidizing system. The defect manifested itself in a Km for trimethylamine which was five times that characteristic of normal enzyme preparation.
T, Higgins +3 more
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