Results 121 to 130 of about 453,912 (274)

PCOS without hyperandrogenism is associated with higher plasma Trimethylamine N-oxide levels

open access: yesBMC Endocrine Disorders, 2020
Background Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder, and its pathogenesis is still under debate. Trimethylamine-N-oxide (TMAO) is a small, organic compound generated by the gut microbiome with a hypothesized relation to ...
Jiayu Huang   +3 more
doaj   +1 more source

Trimethylamine-N-oxide (TMAO) as Novel Potential Biomarker of Early Predictors of Metabolic Syndrome

open access: yesNutrients, 2018
There is a mechanistic link between the gut-derived metabolite trimethylamine-N-oxide (TMAO) and obesity-related diseases, suggesting that the TMAO pathway may also be linked to the pathogenesis of obesity.
L. Barrea   +9 more
semanticscholar   +1 more source

The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer.

open access: yesCell Metabolism, 2022
Hai Wang   +19 more
semanticscholar   +1 more source

Trimethylamine‐N‐oxide promotes brain aging and cognitive impairment in mice

open access: yesAging Cell, 2018
Gut microbiota can influence the aging process and may modulate aging‐related changes in cognitive function. Trimethylamine‐N‐oxide (TMAO), a metabolite of intestinal flora, has been shown to be closely associated with cardiovascular disease and other ...
Dang Li   +11 more
semanticscholar   +1 more source

Impaired renal function and dysbiosis of gut microbiota contribute to increased trimethylamine-N-oxide in chronic kidney disease patients

open access: yesScientific Reports, 2017
Chronic kidney disease (CKD) patients have an increased risk of cardiovascular diseases (CVDs). The present study aimed to investigate the gut microbiota and blood trimethylamine-N-oxide concentration (TMAO) in Chinese CKD patients and explore the ...
Kaiyu Xu   +9 more
semanticscholar   +1 more source

Fasting and postprandial trimethylamine N ‐oxide in sedentary and endurance‐trained males following a short‐term high‐fat diet [PDF]

open access: gold, 2021
Cortney Steele   +6 more
openalex   +1 more source

Trimethylamine N -Oxide

open access: yes
Recent evidence, including massive gene-expression analysis and a wide-variety of other multi-omics approaches, demonstrates an interplay between gut microbiota and the regulation of plasma lipids. Gut microbial metabolism of choline and -carnitine results in the formation of trimethylamine (TMA) and concomitant conversion into trimethylamine- N -oxide
Canyelles, Marina||   +5 more
openaire   +1 more source

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