Results 131 to 140 of about 33,642 (251)

Effect of urea and tmao on lipid bilayers

European Pharmaceutical Journal, 2017
We study the effect of the osmolytes, Urea and trimethylamine-N-oxide (TMAO) on POPE (1-palmitoyl-2-oleoyl-sn-glycero-3- phosphoethanolamine) lipid membranes using SAXS/WAXS and DSC.
Valerio J., Bernstorff S., Funari S.S.
doaj   +1 more source

Effects of Weight Loss Interventions on Gut Microbiota‐Derived Metabolites Linked to Cardiometabolic Health: A Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
ABSTRACT Background Gut microbiota‐derived metabolites are emerging as potential mediators between obesity and cardiometabolic conditions. While weight loss interventions modify microbiota composition, their effects on systemic microbial metabolites remain unclear.
Fernando Q. Iorra, Leonardo André Swarowsky Loebens, Andrea Auler, Eduarda Caroline Tasso Nascimento, Beatriz D. Schaan, Patrícia Martins Bock   +5 more
wiley   +1 more source

Lactobacillus Is Associated With Disease in Pulmonary Arterial Hypertension: A Prospective Cohort Study

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Study overview: simultaneous right heart catheterization, gut microbiome analysis, and plasma blood metabolomics in a cohort of prevalent pulmonary arterial hypertension patients. Key findings: gut microbial Lactobacillus species associated with altered gut‐derived metabolite levels, superior measures of right ventricular structure and function, and ...
Arun Jose, Senu Apewokin, Nicholas J. Ollberding, Qing Duan, Jennifer Trannguyen, Sasha Z. Prisco, Thenappan Thenappan, Anna R. Hemnes, Jean M. Elwing   +8 more
wiley   +1 more source

Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
This review summarizes how maternal health and nutrition shape gut microbiota via epigenetics to regulate embryonic development. It highlights microbiota‐embryo interactions, disruption by prenatal chemical exposures, and personalized nutrition for disease prevention, offering novel insights and therapeutic targets.
Shoulong Xu, Yanjiao Huang, Chenyue Hu, Wenli Ding, Zhenwei Pu, Qiang Li, Zhiliang Xu   +6 more
wiley   +1 more source

The roles of CymA in support of the respiratory flexibility of Shewanella oneidensisMR-1 [PDF]

, 2012
Akagawamatsushita, Atkinson, Beliaev, Beliaev, Bordi, Burns, Cruz-Garcia, David J. Richardson, Dos Santos, Duncan G.G. McMillan, Firer-Sherwood, Gao, Gates, Gescher, Gralnick, Itoh, James K. Fredrickson, John M. Zachara, Julea N. Butt, Lars J.C. Jeuken, Liang Shi, Lies, Maier, Marritt, McMillan, Myers, Myers, Myers, Myers, Pinchuk, Pinchuk, Pitts, Ross, Schuetz, Schutz, Schwalb, Shi, Shirodkar, Simon, Sophie J. Marritt, Sundararajan, Venkateswaran   +41 more
core   +1 more source

Too close for comfort: Self‐crowding transforms protein structure and stability beyond volume exclusion

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Proteins operate in crowded physiological environments, yet their conformational and oligomeric states are largely inferred from experiments performed under dilute buffer conditions. Here, we show that for lysozyme (LYS) and bovine serum albumin (BSA), self‐crowding at physiologically relevant concentrations alters protein structure and ...
Gil I. Olgenblum, Yehonatan N. Levy, Daniel Harries   +2 more
wiley   +1 more source

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, Volume 13, Issue 25, 4 May 2026.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1136-1140, May 2026.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Gut Dysbiosis as a Shared Mechanism in Obesity and Hypertension: Exploring a Promising Therapeutic Avenue

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 3, May 2026.
This review synthesises current knowledge on gut microbiome involvement in obesity and hypertension, evaluates microbiome‐based therapeutic strategies, and identifies critical research gaps to guide future investigations aimed at mitigating the dual pandemics.
Andrej Belančić, Almir Fajkić, Yusuf Ziya Sener, Ana Jelaković, Lejla Alić, Elvira Meni Maria Gkrinia, Donatella Verbanac, Bojan Jelaković   +7 more
wiley   +1 more source

High‐Adhesion Quadruple Hydrogen‐Bonded Ionogels: A Dual‐Function Platform for Gesture Recognition and Real‐Time NH3 Detection in Multiscenario

ENERGY &ENVIRONMENTAL MATERIALS, Volume 9, Issue 3, May 2026.
Quadruple hydrogen‐bonded high‐adhesion ionogels for gesture recognition and real‐time NH3 sensing. Ionogels have garnered significant attention in flexible sensing due to their outstanding mechanical properties, conductivity, and stability. However, establishing a robust and stable adhesive interface with various substrates remains a significant ...
Haohao Lin, Xiaotong Ma, Zihao Chen, Long Yang, Zitong Kan, Ruochen An, Lin Xu, Zhiyong Chang   +7 more
wiley   +1 more source