Results 161 to 170 of about 14,468,554 (196)

A comparative study of trimethylamine-N-oxide biosynthesis

Biochimica et Biophysica Acta, 1963
A broad spectrum of species of plants and animals have been examined for their ability to convert trimethylamine to its N-oxide. Of the animal species studied, and under the conditions used in this investigation, trimethylamine-N-oxide synthesis from trimethylamine seems generally to be restricted to the vertebrates.
J R, BAKER, A, STRUEMPLER, S, CHAYKIN
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Trimethylamine N-Oxide in Aquatic Foods

Journal of Agricultural and Food Chemistry
Trimethylamine N-oxide (TMAO), a characteristic nonprotein nitrogen compound, is widely present in seafood, which exhibits osmoregulatory effects for marine organisms in vivo and plays an important role in aquaculture and aquatic product preservation. However, much attention has been focused on the negative effect of TMAO since it has recently emerged ...
Xiaoyue Li, Chengcheng Wang, Teruyoshi Yanagita, Changhu Xue, Tiantian Zhang, Yuming Wang   +5 more
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Trimethylamine N-Oxide (TMAO), Diet and Cardiovascular Disease

Current Atherosclerosis Reports, 2021
The association between plasma Trimethylamine N-Oxide (TMAO), diet and risk for cardiovascular disease (CVD) is still not fully understood. While epidemiologic research shows a causal relationship between plasma TMAO concentrations and CVD risk, the role of dietary precursors in determining plasma concentrations of TMAO and biomarkers for CVD is ...
Minu S. Thomas, Maria Luz Fernandez
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The role of trimethylamine‐N‐Oxide in the development of Alzheimer's disease

Journal of Cellular Physiology, 2021
Abstract Alzheimer's disease is associated with multiple risk factors and is the most common type of dementia. Trimethylamine‐N‐oxide (TMAO), a gut microbiota metabolite derived from dietary choline and carnitine, has recently been identified as a potential risk factor of Alzheimer's disease.
Nida Buawangpong, Kanokporn Pinyopornpanish, Natthapat Siri‐Angkul, Nipon Chattipakorn, Siriporn C. Chattipakorn   +4 more
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Trimethylamine N-oxide synthesis: A human variant

Biochemical Medicine, 1972
Abstract A 6-year-old girl exhibiting a variety of clinical symptoms including an apparant inability to metabolize trimethylamine has been shown to possess a defective liver trimethylamine oxidizing system. The defect manifested itself in a Km for trimethylamine which was five times that characteristic of normal enzyme preparation.
T, Higgins, S, Chaykin, K B, Hammond, J R, Humbert   +3 more
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A Genetic polymorphism of the N-oxidation of trimethylamine in humans

Clinical Pharmacology and Therapeutics, 1987
Trimethylamine (TMA) and its N-oxide (TMAO) are normal components of human urine. They are present in the diet and also derived from the enterobacterial metabolism of precursors such as choline. Dietary TMA is almost entirely metabolized to and excreted as TMAO.
M, Al-Waiz, R, Ayesh, S C, Mitchell, J R, Idle, R L, Smith   +4 more
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The effect of trimethylamine N-oxide on RNase a stability

Journal of Thermal Analysis and Calorimetry, 2007
The thermal stability of bovine pancreatic ribonuclease (RNase A) has been investigated in the presence of trimethylamine N-oxide (TMAO), a naturally occurring osmolyte, by means of differential scanning calorimetry (DSC) and circular dichroism (CD) measurements at neutral and acid pH conditions.
F. FOGLIA, CARULLO, PAOLA, DEL VECCHIO, POMPEA GIUSEPPINA GRAZIA   +2 more
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Trimethylamine N-oxidation in Turkish women with bacterial vaginosis

Pharmacogenetics, 1996
Bacterial vaginosis (BV) is the most common cause of vaginal discharge in women of child-bearing age. A common symptom of this condition is a fishy-smelling vaginal discharge. Trimethylamine (TMA) is the substance which is primarily responsible for this distinctive odour.
Green, RL, Mellon, T, Akyol, D, Sardas, S, Cholerton, S, Gokmen, O   +5 more
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Trimethylamine N-Oxide and Risk of Cardiovascular Disease and Mortality

Current Nutrition Reports, 2018
Trimethylamine N-oxide (TMAO) is a gut microbiota-dependent metabolite produced from choline and phosphatidylcholine. Trimethylamine N-oxide was found associated with enhanced atherosclerosis and thrombosis in vitro and in vivo. We summarized available clinical studies which investigated TMAO's role in predicting prognostic outcomes, including ...
Chanavuth, Kanitsoraphan, Pattara, Rattanawong, Suranut, Charoensri, Vichai, Senthong   +3 more
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Trimethylamine-N-oxide and its biological variations in vegetarians

European Journal of Nutrition, 2016
Restriction of animal foods and choline may affect plasma trimethylamine-N-oxide (TMAO). In vegetarians, we investigated the association between TMAO concentrations and the strictness of the diet or sex. We also studied the biological variations of TMAO in vegans.Concentrations of plasma TMAO and choline metabolites were measured in 38 vegans and 67 ...
Obeid, Rima, Awwad, Hussain Mohamad, Keller, Markus, Geisel, Juergen   +3 more
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