Results 171 to 180 of about 561,219 (291)

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Emerging Trends in Organic Photoreactions Utilizing Disulfides

European Journal of Organic Chemistry, Volume 29, Issue 21, 4 June 2026.
Disulfides are versatile, nontoxic alternatives to metal photocatalysts. This review explores their role as photoactivated thiyl‐radical precursors and bifunctional catalysts (HAT/electron shuttling) in diverse transformations. Strategies for electronic tuning and development into recyclable heterogeneous materials are highlighted for sustainable ...
Sunil Kumar, Bolormaa Bayarkhuu, Hong Y. Cho, Jeehye Byun   +3 more
wiley   +1 more source

Anion Mobility Renormalization Reveals Backbone‐Dependent Tortuosity in Anion Exchange Membranes

ChemElectroChem, Volume 13, Issue 11, 3 June 2026.
Backbone polarity governs nanophase separation and tortuosity in anion exchange membranes (AEMs). The anion mobility across PPO‐ and PSU‐based ionomer membranes with quaternary ammonium groups depends exponentially on concentration. Extracted porosity–tortuosity ratios reveal lower tortuosity in PPO due to stronger PSU hydrophilicity.
Philippe Knauth, Maria Luisa Di Vona
wiley   +1 more source

Electrolyte Design Strategies for Static Shuttle‐Free and Long‐Life Aqueous Zinc‐Iodine Batteries

Advanced Functional Materials, Volume 36, Issue 45, 5 June 2026.
This review systematically summarizes recent advances in electrolyte design for static aqueous Zn‐I2 batteries, highlighting solvation regulation and interfacial engineering strategies to control reaction kinetics, suppress iodine shuttling, enhance energy density, and stabilize multi‐electron iodine redox chemistry for durable, high‐performance energy
Qianqin Zhou, Fan Zhang, Ting Liao, Ziqi Sun   +3 more
wiley   +1 more source

Multifunctional Bio‐Based Packaging for Perishable Foods: Structural Design, Scalable Fabrication, and Versatile Applications

Advanced Materials, Volume 38, Issue 33, 12 June 2026.
An overview of design principles and scalable fabrication strategies for multifunctional bio‐based packaging. Radiative cooling films, modified‐atmosphere films/membranes, active antimicrobial/antioxidant platforms, intelligent optical/electrochemical labels, and superhydrophobic surfaces are co‐engineered from material chemistry to mesoscale structure
Lei Zhang, Jiaqi Zhang, Mei Cui, Wei Qi, Renliang Huang, Rongxin Su, Kai Zhang   +6 more
wiley   +1 more source

SIRT1: Protean roles at the nexus of health, disease, and therapeutics

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
SIRT1 serves as a central regulator linking metabolism, stress responses, and disease. It influences diverse processes, including transcriptional and posttranscriptional gene expression and protein activity, inflammation, mitochondrial function, and cell survival, through the deacetylation of multiple protein targets. While SIRT1 often plays protective
Brahim Chaqour
wiley   +1 more source

Lactobacillus Is Associated With Disease in Pulmonary Arterial Hypertension: A Prospective Cohort Study

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Study overview: simultaneous right heart catheterization, gut microbiome analysis, and plasma blood metabolomics in a cohort of prevalent pulmonary arterial hypertension patients. Key findings: gut microbial Lactobacillus species associated with altered gut‐derived metabolite levels, superior measures of right ventricular structure and function, and ...
Arun Jose, Senu Apewokin, Nicholas J. Ollberding, Qing Duan, Jennifer Trannguyen, Sasha Z. Prisco, Thenappan Thenappan, Anna R. Hemnes, Jean M. Elwing   +8 more
wiley   +1 more source

Onium ions. 18. Static protonated and exchanging diprotonated ambivalent heteroorganic systems. hydroxylamines, acetone oxime, and dimethyl sulfoxide [PDF]

, 1978
Andreozzi, Patricia, Donovan, Daniel J., Klopman, Gilles, Lin, Henry C., Mayr, Herbert, Olah, George A.   +5 more
core   +1 more source

Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
This review summarizes how maternal health and nutrition shape gut microbiota via epigenetics to regulate embryonic development. It highlights microbiota‐embryo interactions, disruption by prenatal chemical exposures, and personalized nutrition for disease prevention, offering novel insights and therapeutic targets.
Shoulong Xu, Yanjiao Huang, Chenyue Hu, Wenli Ding, Zhenwei Pu, Qiang Li, Zhiliang Xu   +6 more
wiley   +1 more source

Evaluation of the Effects of Wax Films Formulated With Thyme and Laurel Essential Oils on Chemical and Microbiological Quality Characteristics of Rainbow Trout Fillets During Storage

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This graphical abstract illustrates the superior preservative effects of essential oil‐enriched beeswax coatings on rainbow trout fillets compared to conventional methods. The application of these natural active coatings, particularly with 4% laurel essential oil, significantly slowed biochemical spoilage, improved textural attributes, and preserved ...
Ayşe Janseli Denizkara, Gökhan Akarca, Ramazan Şevik, Çiğdem Aşçioğlu, Senem Güner   +4 more
wiley   +1 more source