Results 211 to 220 of about 33,642 (251)

Mechanisms and Intervention Strategies of Trimethylamine N-Oxide in Abdominal Aortic Aneurysm.

Cardiology
Abudureheman D, Janaerbieke S, Song Y, Han S, Yimaer W, Wang H.   +5 more
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Trimethylamine N-Oxide (TMAO), Diet and Cardiovascular Disease

Current Atherosclerosis Reports, 2021
The association between plasma Trimethylamine N-Oxide (TMAO), diet and risk for cardiovascular disease (CVD) is still not fully understood. While epidemiologic research shows a causal relationship between plasma TMAO concentrations and CVD risk, the role of dietary precursors in determining plasma concentrations of TMAO and biomarkers for CVD is ...
Minu S. Thomas, Maria Luz Fernandez
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Genetic polymorphism of trimethylamine N-oxidation

Pharmacology & Therapeutics, 1990
Example of a food idiosyncracy, known to represent a pharmacogenetic polymorphism: trimethylaminuria of «fish-odour syndrome». Primary trimethylaminuria must be distinguished from the trimethylaminurias which are non-genetic in origin and which are secondary to other factors such as renal or hepatic disease or overload with trimethylamine ...
R, Ayesh, R L, Smith
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Trimethylamine/Trimethylamine-N-Oxide as a Key Between Diet and Cardiovascular Diseases

Cardiovascular Toxicology, 2021
Trimethylamine (TMA) is a gut microbiota-derived metabolite which comes from diets rich of choline, betaine or L-carnitine and could be further converted to Trimethylamine-N-oxide (TMAO) in the liver. As the function of gut microbiota and its metabolites being explored so far, studies suggest that TMAO may be a potential risk factor of cardiovascular ...
Siyu He, Hong Jiang, Caili Zhuo, Wei Jiang   +3 more
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Trimethylamine-N-oxide Biosynthesis in the Bullfrog

Nature, 1966
THE comparative aspects of the mechanism of oxygenations dependent on molecular oxygen have recently been investigated using the biosynthesis of trimethylamine-N-oxide as a model1. That investigation raised a number of questions beyond the presence of the enzymatic activity in a given organism.
K, Murray, K, Chakraverty, S, Chaykin
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Trimethylamine N-oxide synthesis: A human variant

Biochemical Medicine, 1972
Abstract A 6-year-old girl exhibiting a variety of clinical symptoms including an apparant inability to metabolize trimethylamine has been shown to possess a defective liver trimethylamine oxidizing system. The defect manifested itself in a Km for trimethylamine which was five times that characteristic of normal enzyme preparation.
T, Higgins, S, Chaykin, K B, Hammond, J R, Humbert   +3 more
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Trimethylamine N-Oxide in Aquatic Foods

Journal of Agricultural and Food Chemistry
Trimethylamine N-oxide (TMAO), a characteristic nonprotein nitrogen compound, is widely present in seafood, which exhibits osmoregulatory effects for marine organisms in vivo and plays an important role in aquaculture and aquatic product preservation. However, much attention has been focused on the negative effect of TMAO since it has recently emerged ...
Xiaoyue Li, Chengcheng Wang, Teruyoshi Yanagita, Changhu Xue, Tiantian Zhang, Yuming Wang   +5 more
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Microbial Dimethylsulfoxide and Trimethylamine-N-Oxide Respiration

2005
Over the last two decades, the biochemistry and genetics of dimethylsulfoxide (DMSO) and trimethylamine-N-oxide (TMAO) respiration has been characterised, particularly in Escherichia coli marine bacteria of the genus Shewanella and the purple phototrophic bacteria, Rhodobacter sphaeroides and R. capsulatus.
McCrindle, S. L., Kappler, U., McEwan, A. G.   +2 more
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Thermal conversion of trimethylamine-N-oxide to trimethylamine and dimethylamine in squids

Food and Chemical Toxicology, 1985
The levels of dimethylamine-nitrogen (DMA-N), trimethylamine-nitrogen (TMA-N) and trimethylamine-N-oxide-nitrogen (TMAO-N) were determined in five species of dried squid. Each sample contained extremely high levels of TMAO-N (2558-8064 ppm) and moderate amounts of TMA-N (121-503 ppm) and DMA-N (124-373 ppm). Over 90% of TMAO-N in squid was converted to
J K, Lin, D C, Hurng
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A comparative study of trimethylamine-N-oxide biosynthesis

Biochimica et Biophysica Acta, 1963
A broad spectrum of species of plants and animals have been examined for their ability to convert trimethylamine to its N-oxide. Of the animal species studied, and under the conditions used in this investigation, trimethylamine-N-oxide synthesis from trimethylamine seems generally to be restricted to the vertebrates.
J R, BAKER, A, STRUEMPLER, S, CHAYKIN
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