Results 11 to 20 of about 10,278 (188)

Trimethylamine N-Oxide (TMAO) and Trimethylamine (TMA) Determinations of Two Hadal Amphipods

Journal of Marine Science and Engineering, 2022
Hadal trenches are a unique habitat with high hydrostatic pressure, low temperature and scarce food supplies. Amphipods are the dominant scavenging metazoan species in this ecosystem.
Qi Liu, Shouwen Jiang, Wenhao Li, Binbin Pan, Qianghua Xu   +4 more
doaj   +2 more sources

The gene expression and bioinformatic analysis of choline trimethylamine-lyase (CutC) and its activating enzyme (CutD) for gut microbes and comparison with their TMA production levels

Current Research in Microbial Sciences, 2021
Recent studies revealed that some intestinal microorganisms anaerobically convert choline to trimethylamine (TMA) by choline TMA-lyase (cutC). TMA is further oxidized to trimethylamine-N-oxide (TMAO), by the liver enzyme flavin-dependent monooxygenase 3 (
Latha Ramireddy, Hau-Yang Tsen, Yu-Chen Chiang, Chen Ying Hung, Fu-Chih Chen, Hsien- Tung Yen   +5 more
doaj   +3 more sources

Stilbene-based derivatives as potential inhibitors of trimethylamine (TMA)-lyase affect gut microbiota in coronary heart disease. [PDF]

Food Sci Nutr, 2023
AbstractCoronary heart disease (CHD) is defined by atherosclerosis, which may result in stenosis or blockage of the arterial cavity, leading to ischemic cardiac diseases such as angina and myocardial infarction (MI). Accumulating evidence indicates that the gut microbiota play a critical role in the initiation and progression of CHD.
Li J, Huang P, Cheng W, Niu Q.
europepmc   +4 more sources

Screening freshness of seafood by measuring trimethylamine (TMA) levels using helium-plasma ionization mass spectrometry (HePI-MS) [PDF]

Journal of Analytical Science and Technology, 2019
Background Trimethylamine (TMA) is a marker used for monitoring the quality of seafood because it is the primary component of the “fishy” odor. Methods The levels of TMA in seafood samples were directly measured by helium-plasma ionization mass ...
Isuru S. Herath, Thomas E. O’Donnell, Julius Pavlov, Athula B. Attygalle   +3 more
doaj   +2 more sources

Electrophoretic Determination of Trimethylamine (TMA) in Biological Samples as a Novel Potential Biomarker of Cardiovascular Diseases Methodological Approach. [PDF]

Int J Environ Res Public Health, 2021
In competitive athletes, the differential diagnosis between nonpathological changes in cardiac morphology associated with training (commonly referred to as “athlete’s heart”) and certain cardiac diseases with the potential for sudden death is an important and not uncommon clinical problem.
Konop M, Rybka M, Waraksa E, Laskowska AK, Nowiński A, Grzywacz T, Karwowski WJ, Drapała A, Kłodzińska EM.   +8 more
europepmc   +4 more sources

Exposure Patterns of Multiple Pesticides and Urinary Alterations of Trimethylamine (TMA) and Trimethylamine N-Oxide (TMAO) among Pregnant Women. [PDF]

Environ Health (Wash), 2023
Environmental exposure to pesticides is widespread and commonly occurs in mixtures, and pregnant women are particularly concerned. Trimethylamine N-oxide (TMAO), a dietary-derived catabolite linked to cardiometabolic disease, may be influenced by pesticide exposure.
Ding J, Dai Y, Wang Z, Zhang B, Xu S, Guo J, Qi X, Lu D, Chang X, Wu C, Zhang J, Zhou Z.   +11 more
europepmc   +3 more sources

Isolation and Characterization of the Trimethylamine (TMA)-Degrading <i>Microbacterium lacticum</i> Strain PM-1. [PDF]

Microorganisms
Trimethylamine (TMA) is a common malodorous pollutant known for its detrimental effects on both the natural environment and human health. In this study, strain PM-1 was successfully isolated from activated sludge in a sewage treatment plant and identified as the first Microbacterium lacticum capable of degrading TMA.
Feng P, Zhang L, Wu Y, Hu Y, Chen W, Liu Y, Yang J.   +6 more
europepmc   +3 more sources

The roles of trimethylamine-N-oxide in atherosclerosis and its potential therapeutic aspect: A literature review

Biomolecules & Biomedicine, 2023
Current research supports the evidence that the gut microbiome (GM), which consist of gut microbiota and their biologically active metabolites, is associated with atherosclerosis development.
Yudi Her Oktaviono, Ariikah Dyah Lamara, Pandit Bagus Tri Saputra, Jannatin Nisa Arnindita, Diar Pasahari, Mahendra Eko Saputra, Ni Made Adnya Suasti   +6 more
doaj   +1 more source

A Pomegranate Polyphenol Extract Suppresses the Microbial Production of Proatherogenic Trimethylamine (TMA) in an In Vitro Human Colon Model. [PDF]

Mol Nutr Food Res
ABSTRACTHigh circulating levels of trimethylamine N‐oxide (TMAO) are linked to metabolic diseases, adverse outcomes after heart failure, and atherogenic effects in animal models and in human subjects. l‐Carnitine and choline are major dietary precursors of TMAO.
Haarhuis JE, Day-Walsh P, Shehata E, Savva GM, Peck B, Philo M, Kroon PA.   +6 more
europepmc   +4 more sources

β-sitosterol inhibits trimethylamine production by regulating the gut microbiota and attenuates atherosclerosis in ApoE–/– mice

Frontiers in Cardiovascular Medicine, 2022
The intestinal microbial metabolite trimethylamine (TMA), which is activated by flavin monooxygenase (FMO) to produce trimethylamine-N-oxide (TMAO), has been implicated in the pathogenesis of atherosclerosis (AS), leading to the development of ...
Weiping Wu, Wugao Liu, Huafu Wang, Wei Wang, Weihua Chu, Jing Jin   +5 more
doaj   +1 more source