Circular RNA Rftn1 Promotes Cardiac Hypertrophy In Vitro and In Vivo by Sponging miRNA-1192 to Upregulate Tripartite Motif Protein 25 and 41. [PDF]
Liu G +6 more
europepmc +1 more source
TRIM28 Is an E3 Ligase of IRP2 Suppressing Ischemia/Reperfusion-Induced Myocardial Ferroptosis. [PDF]
Zhu K +21 more
europepmc +1 more source
FBXO22 Suppresses Oxidative Stress-Induced ASK1 Activation and Cell Death via Ubiquitination-Dependent Degradation of TRIM48. [PDF]
Kashiwabara N +9 more
europepmc +1 more source
Mechanism of and research progress on alterations in the RET gene in thyroid cancer (Review). [PDF]
Wei M, Wang R, Qian J, Fang Q, Tao J.
europepmc +1 more source
Roles and Mechanisms of TRIM Family Proteins in Inflammation in the Brain and Beyond. [PDF]
Gerasimova T +7 more
europepmc +1 more source
Insights into the membrane repair mechanism by the coiled-coil-mediated oligomerization of TRIM72. [PDF]
Park SH, Kempf G, Song HK.
europepmc +1 more source
TRIM3 suppressed the tumorigenicity of melanoma cells by ubiquitinating YAP1. [PDF]
Wang YT, Zhao JC, Song DM, Chen JJ.
europepmc +1 more source
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Fish antiviral tripartite motif (TRIM) proteins
Fish and Shellfish Immunology, 2019Tripartite motif (TRIM) family or RBCC proteins comprises characteristic zinc-binding domains (a RING (R), a B-box type 1 (B1) and a B-box type 2 (B2)) and coiled-coil (CC) domain followed by a C-terminus variable domain. There are about 80 different TRIM proteins in human, but more than 200 in zebrafish with several large gene expansions (ftr >70 ...
Jean-Pierre Levraud +2 more
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Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function [PDF]
The human tripartite motif (TRIM) family comprises 70 members, including HIV restriction factor TRIM5α and disease-associated proteins TRIM20 (pyrin) and TRIM21. TRIM proteins have conserved domain architecture but diverse cellular roles. Here, we describe how the C-terminal PRYSPRY domain mediates diverse TRIM functions.
John Trowsdale, Leo James, James Leo C
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