Results 141 to 150 of about 4,964 (161)

Tripartite motif-containing (TRIM) 21 negatively regulates intestinal mucosal inflammation through inhibiting TH1/TH17 cell differentiation in patients with inflammatory bowel diseases

Journal of Allergy and Clinical Immunology, 2018
Tripartite motif-containing (TRIM) 21 has been implicated in the pathogenesis of several types of autoimmune diseases.We sought to elucidate TRIM21 expression in patients with inflammatory bowel diseases (IBDs) and its role in regulating intestinal mucosal inflammation.TRIM21 expression was analyzed in the inflamed mucosa of patients with IBDs by means
Zhanju Liu, Xiaoping Zhang
exaly   +3 more sources

Human immunodeficiency virus type 1 restriction by human-rhesus chimeric tripartite motif 5alpha (TRIM 5alpha) in CD34(+) cell-derived macrophages in vitro and in T cells in vivo in severe combined immunodeficient (SCID-hu) mice transplanted with human fetal tissue.

Human gene therapy, 2008
Species-specific innate resistance against viral infections offers novel avenues for antiviral therapeutics. The retroviral restriction factor TRIM5alpha (tripartite motif 5alpha protein) has been shown to potently restrict human immunodeficiency virus (HIV)-1 infection in otherwise susceptible cell lines and CD34(+) cell-derived macrophages.
Joseph, Anderson, Ramesh, Akkina
openaire   +2 more sources

MyoTRIM, an engineered tripartite motif (TRIM) protein, recapitulates canonical phosphatidylserine binding and enhances cell membrane resealing capacity

Physiology
Duchenne Muscular Dystrophy (DMD) is the most prevalent hereditary neuromuscular disease and involves progressive muscle degeneration that contributes to early death. DMD is caused by mutations in the dystrophin gene, which eliminates its expression and leads to compromised structural integrity of the muscle cell plasma membrane.
Miguel A. Lopez Perez, Kassidy K. Banford, Hannah R. Bulgart, Gianni Giarrano, Noah Weisleder   +4 more
openaire   +1 more source

Bioinformatics analysis of immune infiltrates and tripartite motif (TRIM) family genes in hepatocellular carcinoma

Journal of Gastrointestinal Oncology, 2022
Shengjie Jin, Daoyuan Tu, Bingbing Su
exaly  

Comprehensive profiling of the TRIpartite motif family to identify pivot genes in hepatocellular carcinoma

Cancer Medicine, 2022
Senxiang Yan, Lingyun Wu, Xin Yin
exaly  

127 Characterization of Tripartite-Motif (TRIM) 22-Mediated Inhibition of HIV-1 Transcription

JAIDS Journal of Acquired Immune Deficiency Syndromes, 2011
A Kajaste-Rudnitski, S Marell, T Pertel, G Poli, J Luban, E Vicenzi   +5 more
openaire   +1 more source

Author response for "Role of the tripartite motif-containing (TRIM) family of proteins in insulin resistance and related disorders"

2023
null Chen, Jianrong, null Feng, Xianjie, null Zhou, Xu, null Li, Yong   +3 more
openaire   +1 more source

Tripartite motif‐containing 54 promotes gastric cancer progression by upregulating K63‐linked ubiquitination of filamin C

Asia-Pacific Journal of Clinical Oncology, 2022
Liang Chen
exaly  

Review for "Role of the tripartite motif-containing (TRIM) family of proteins in insulin resistance and related disorders"

2023
openaire   +2 more sources

Protéines à motif tripartite (TRIM) chez le porc (Sus scrofa) et réplication du rétrovirus endogène porcin

Les études des interactions entre cellules hôtes et rétrovirus ont conduit à définir le concept de restriction virale dont les facteurs constituent une part de l'immunité innée des cellules hôtes. Ces facteurs contribuent au contrôle des rétrovirus endogènes (ERV) dont l'émergence peut être associée à certaines pathologies telles que des leucémies ou ...
openaire   +1 more source