Results 51 to 60 of about 2,448 (132)

[Tripeptidyl peptidase 1 in patients with late infantile neuronal ceroid lipofuscinosis].

Anales de pediatria (Barcelona, Spain : 2003), 2012
Neuronal ceroid lipofuscinoses are a group of inherited autosomal recessive lysosomal diseases, most commonly found in infancy. These are neuropathologically characterised by accumulation of an autofluorescent lipopigment in neurons and other cells.
L Miranda, Contreras, W Delgado, Luengo, N, Zerpa, J Chacín, Hernández, C J, Chávez, S González, Ferrer   +5 more
openaire   +1 more source

Corrigendum to “Upregulation of tripeptidyl-peptidase 1 by 3-hydroxy-(2,2)-dimethyl butyrate, a brain endogenous ligand of PPARα: Implications for late-infantile Batten disease therapy” [Neurobiology of Disease 127 (2019) 362–373]

Neurobiology of Disease
Sudipta Chakrabarti, Sujyoti Chandra, Avik Roy, Madhuchhanda Kundu, Kalipada Pahan   +4 more
doaj   +2 more sources

Supplementary Data 1 from Tripeptidyl-peptidase II Controls DNA Damage Responses and <i>In vivo</i> γ-Irradiation Resistance of Tumors

, 2023
Supplementary Data 1 from Tripeptidyl-peptidase II Controls DNA Damage Responses and <i>In vivo</i> γ-Irradiation Resistance of ...
Rickard Glas, Alf Grandien, Steven E. Applequist, Rajender Naredla, Brita Künert, Lu Lei, Xu Hong   +6 more
openaire   +1 more source

Structure-function analysis of Sedolisins: evolution of tripeptidyl peptidase and endopeptidase subfamilies in fungi

BMC Bioinformatics, 2018
Background Sedolisins are acid proteases that are related to the basic subtilisins. They have been identified in all three superkingdoms but are not ubiquitous, although fungi that secrete acids as part of their lifestyle can have up to six paralogs ...
Facundo Orts, Arjen ten Have
doaj   +1 more source

Additional file 1 of Tripeptidyl peptidase I promotes human endometrial epithelial cell adhesive capacity implying a role in receptivity

, 2020
Additional file 1: SupplementaryTable 1. Primers.
Santos, Leilani L., Ling, Cheuk Kwan, Dimitriadis, Evdokia   +2 more
openaire   +1 more source

Exploring the Structural Design, Antibacterial Activity, and Molecular Docking of Newly Synthesized Zn(II) Complexes with NNO-Donor Carbazate Ligands

Molecules
The present work reports the synthesis and structural design of three novel Zn(II) complexes [Zn(L1)(CH3COO)(H2O)] (1), [Zn(L2)2] (2), and [Zn(L3)2] (3) with carbazate ligands, 2-acetylpyridine-methylcarbazate (HL1), 2-acetylpyridine-ethylcarbazate (HL2),
Claudia C. Gatto, Daniel J. de Siqueira, Eduardo de A. Duarte, Érica C. M. Nascimento, João B. L. Martins, Mariana B. Santiago, Nagela B. S. Silva, Carlos H. G. Martins   +7 more
doaj   +1 more source

Temperature modulates the secretome of the phytopathogenic fungus Lasiodiplodia theobromae

Frontiers in Plant Science, 2016
Environmental alterations modulate host-microorganism interactions. Little is known about how climate changes can trigger pathogenic features on symbiont or mutualistic microorganisms.
Carina Félix, Ana Sofia Duarte, Rui Vitorino, Rui Vitorino, Ana Catarina Guerreiro, Pedro Domingues, Antonio CM Correia, Artur Alves, Ana Cristina Esteves   +8 more
doaj   +1 more source

A current view of mitochondria damage and the diversity of lipopigment inclusions in neuronal ceroid lipofuscinose type 2 from rectal biopsy

Folia Neuropathologica
Neuronal ceroid lipofuscinoses (NCLs) are a growing group of neurodegenerative storage diseases, in which specific features are sought to facilitate the creation of a universal diagnostic algorithm in the future. In our ultrastructural studies, the group
Paulina Felczak, Aleksandra Kuźniar-Pałka, Agnieszka Ługowska, Elżbieta Stawicka, Sylwia Tarka, Hanna Mierzewska   +5 more
doaj   +1 more source

Two-year follow-up of gait and postural control following initiation of recombinant human tripeptidyl intracerebroventricular enzyme replacement therapy in two atypical CLN2 patients

Scientific Reports
Neuronal ceroid lipofuscinosis type 2 (CLN2) is a rapidly progressive neurodegenerative disorder leading to premature mortality. Ambulatory CLN2 patients typically receive standard of care treatment through biweekly intracerebroventricular (ICV) enzyme ...
Rahul Soangra, Marybeth Grant-Beuttler, Harriet Chang, Raymond Y. Wang   +3 more
doaj   +1 more source

Case Report: The window that closed too soon: lessons from a late CLN2 diagnosis and death of a 9-year-old boy

Frontiers in Genetics
A class of progressive, autosomal recessive neurodegenerative diseases known as neuronal ceroid lipofuscinoses (NCLs) are brought on by lysosomal protein or enzyme dysfunction.
Anna Bryzik, Dawid Larysz, Patrycja Larysz, Julia Izabela Karpierz, Justyna Paprocka   +4 more
doaj   +1 more source