Results 101 to 110 of about 46,021 (301)

Bioinspired Synthesis of Twin abeo‐Steroids Bufogargarizins A and B via a Divergent Intramolecular Aldol Addition Reaction

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Twin natural products. This manuscript describes a concise biomimetic synthesis of twin abeo‐steroids bufogargarizins A and B with an unusual [7.5.6.5] and [5.7.6.5] skeletons in 19 steps (LLS). The described synthetic approach features the application of a bioinspired regiodivergent intramolecular aldol addition reaction and a selective singlet oxygen‐
Zoey J. Surma, Volodymyr Hiiuk, Eugene Zviagin, Yaxin Ouyang, Alex Chacko, Fengrui Qu, Paul M. Zimmerman, Pavel Nagorny   +7 more
wiley   +2 more sources

Multi-Omics Analysis in Mouse Primary Cortical Neurons Reveals Complex Positive and Negative Biological Interactions Between Constituent Compounds of Centella asiatica

Pharmaceuticals
Background: A water extract of the Ayurvedic plant Centella asiatica (L.) Urban, family Apiaceae (CAW), improves cognitive function in mouse models of aging and Alzheimer’s disease and affects dendritic arborization, mitochondrial activity, and oxidative
Steven R. Chamberlin, Jonathan A. Zweig, Cody J. Neff, Luke Marney, Jaewoo Choi, Liping Yang, Claudia S. Maier, Amala Soumyanath, Shannon McWeeney, Nora E. Gray   +9 more
doaj   +1 more source

The potential of Ganoderma lucidum extracts as bioactive ingredients in topical formulations, beyond its nutritional benefits [PDF]

, 2017
Ganoderma lucidum was characterized in terms of nutritional value and chemical composition. Thereafter, ethanolic Soxhlet extracts were evaluated for antioxidant, anti-inflammatory, antityrosinase, antimicrobial and cytotoxic effects, and further ...
Alves, Maria José, Barreiro, M.F., Barros, Lillian, Calhelha, Ricardo C., Ferreira, Isabel C.F.R., González-Paramás, Ana María, Heleno, Sandrina A., Taofiq, Oludemi   +7 more
core   +1 more source

Triterpene glycosides from Astragalus icmadophilus

Phytochemistry, 2010
Six cycloartane-type triterpene glycosides were isolated from Astragalus icmadophilus along with two known cycloartane-type glycosides, five known oleanane-type triterpene glycosides and one known flavonol glycoside. The structures of the six compounds were established as 3-O-[alpha-L-arabinopyranosyl-(1-->2)-O-3-acetoxy-alpha-L-arabinopyranosyl]-6-O ...
Ibrahim Horo, Erdal Bedir, PERRONE, ANGELA, Fevzi Oezgoekce, PIACENTE, Sonia, Ozgen Alankus Caliskan   +5 more
openaire   +5 more sources

The Effect of Myrtacine and Celastrol‐Enriched Extract on Cutibacterium acnes Extracellular Vesicles

International Journal of Dermatology, EarlyView.
Myrtacine alone, Celastrol‐enriched extract alone, or the combination of both ingredients were added to the culture medium either before (preventive condition) or after (modulating condition) incubation with C. acnes IA1 extracellular vesicles (EVs) from healthy and acne skin in immortalized keratinocytes (HaCaT cells) and human skin explants.
Caroline T. Cheung, Céline Mias, Ugo Lancien, Stéphane Corvec, Valérie Mengeaud, Amir Khammari, Hélène Duplan, Brigitte Dréno   +7 more
wiley   +1 more source

Methodology for the Construction of the Bicyclo[4.3.0]nonane Core

Molecules, 2016
The bicyclo[4.3.0]nonane scaffold, commonly known as a hydrindane, is a common structural motif found in many terpenoid structures and one that remains a challenge for synthetic chemists to elaborate with appropriate regio- and stereo-selectivity.
Nicholas A. Eddy, Pranjali Ichalkaranje
doaj   +1 more source

Chromosome‐Scale Haplotype Genome Assemblies for the Australian Mango ‘Kensington Pride’ and a Wild Relative, Mangifera laurina, Provide Insights Into Anthracnose‐Resistance and Volatile Compound Biosynthesis Genes

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mango (Mangifera indica) is one of the most popular fruits cultivated in tropical and subtropical regions of the world. The availability of reference genomes helps to identify the genetic basis of important traits. Here, we report assembled high‐quality chromosome‐level genomes for the Australian mango cultivar ‘Kensington Pride’ and M ...
Upendra Kumari Wijesundara, Agnelo Furtado, Ardashir Kharabian Masouleh, Natalie L. Dillon, Heather E. Smyth, Robert J. Henry   +5 more
wiley   +1 more source

New Triterpenes from Gymnema sylvestre [PDF]

, 2013
Phytochemical investigation of the aerial parts of Gymnema sylvestre has led to the isolation of seven new triterpenes, six oleane types (5, 7-11) and a new lupane type (12), and of the six known analogues 1-4, 6, and 13.
Garcia-Granados, Granich, Kanetkar, Komalavalli, Neukirch, Porchezhian, Rasoanaivo, Shibata, Shigematsu, Ye, Yoshikawa, Yoshikawa, Yoshikawa, Yoshikawa   +13 more
core   +1 more source

Unveiling protective mechanisms of wild olive (acebuche) oil in retinal pigment epithelial cells with hypertensive phenotype

The Journal of Physiology, EarlyView.
Abstract figure legend Circulating extracellular vesicles (EVs) derived from acebuche (ACE) oil‐ and extra virgin olive oil (EVOO)‐fed mice modulate nitric oxide (NO) metabolism in the retinal pigment epithelial cell line (ARPE19) with a hypertensive phenotype induced by angiotensin II (AngII).
Álvaro Santana‐Garrido, Claudia Reyes‐Goya, Pablo Espinosa‐Martín, Rosa M. Troya‐Toledo, Helder André, Alfonso Mate, Carmen M. Vázquez   +6 more
wiley   +1 more source

The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism

BMC Cancer, 2011
Background Maslinic acid, a pentacyclic triterpene found in the protective wax-like coating of the leaves and fruit of Olea europaea L., is a promising agent for the prevention of colon cancer.
Cascante Marta, Rufino-Palomares Eva E, Lizárraga Daneida, Pachón-Peña Gisela, Reyes-Zurita Fernando J, Lupiáñez José A   +5 more
doaj   +1 more source