Results 91 to 100 of about 88,531 (294)

A Combination of Xanthohumol and Ursolic Acid in the Diet Leads to Synergistic Inhibition of Prostate Cancer Progression

Molecular Carcinogenesis, EarlyView.
ABSTRACT Prostate cancer (PCa) is the second most common cancer and second leading cause of cancer death for American men. Chemoprevention by using phytochemicals offers a promising approach to improve outcomes due to their ability to act on cancer cell metabolism and growth while maintaining low toxicity profiles.
Rachel Clark, Achinto Saha, G. Lavender Hackman, Chelsea A. Friedman, Ruggiero Gorgoglione, Stefano Tiziani, John DiGiovanni   +6 more
wiley   +1 more source

Bardoxolone Methyl: A Comprehensive Review of Its Role as a Nrf2 Activator in Anticancer Therapeutic Applications

Pharmaceuticals
Bardoxolone methyl, also known as CDDO-Me or RTA 402, is a synthetic oleanane triterpenoid that has garnered significant attention as a potent pharmacological activator of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.
Valentina Schiavoni, Tiziana Di Crescenzo, Valentina Membrino, Sonila Alia, Sonia Fantone, Eleonora Salvolini, Arianna Vignini   +6 more
doaj   +1 more source

CYP712K4 Catalyzes the C-29 Oxidation of Friedelin in the Maytenus ilicifolia Quinone Methide Triterpenoid Biosynthesis Pathway.

Plant and Cell Physiology, 2019
The native Brazilian plant Maytenus ilicifolia accumulates a set of quinone methide triterpenoids with important pharmacological properties, among which maytenin, pristimerin and celastrol that accumulate exclusively in the root bark of this medicinal ...
K. Bicalho, M. M. Santoni, P. Arendt, C. Zanelli, M. Furlan, A. Goossens, Jacob Pollier   +6 more
semanticscholar   +1 more source

The Cinderella tree, Quillaja saponaria – A soap story

PLANTS, PEOPLE, PLANET, EarlyView.
Our current understanding of plants has been shaped by the entwining of different cultures. The Chilean soapbark tree, traditionally valued as a source of natural soap, was shown by serendipitous research in France in the 1900s to produce compounds that can boost the immune response to vaccines.
Anne Osbourn
wiley   +1 more source

Three New Ursane-Type Triterpenoids from the Stems of Saprosma merrillii

Molecules, 2013
Three new ursane-type triterpenoids, 3α,6α,30-trihydroxy-ursan-28-oic acid (1), 3α,30-dihydroxy-6-oxo-ursan-28-oic acid (2) and 3α,6α,7α,30-tetrahydroxy-ursan-28-oic acid (3), together with one known triterpenoid, betulinic acid (4), one known ...
Dashuai Zhang, Wenhao Chen, Wenxing Chen, Xiaoping Song, Changri Han, Yan Wang, Guangying Chen   +6 more
doaj   +1 more source

Cassane diterpenoids from lonchocarpus laxiflorus [PDF]

, 2008
This article examines cassane diterpenoids from lonchocarpus ...
Gray, A.I., Igoli, J.O., Letzel, M.C., Nwaji, M.N., Onyiriuka, S.O.   +4 more
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Production of triterpenoid compounds from Ganoderma lucidum spore powder using ultrasound-assisted extraction

Preparative Biochemistry & Biotechnology, 2019
When ingested as a dietary supplement, Ganoderma lucidum spore powders (GLSP) provide various health benefits such as enhanced immunity, liver protection and anti-cancer effects.
Shuang-Fei Shen, Li‐Fang Zhu, Zijing Wu, Guangkun Wang, Z. Ahmad, Ming‐Wei Chang   +5 more
semanticscholar   +1 more source

Asiatic Acid Ameliorates MNNG‐Induced Chronic Atrophic Gastritis by Inhibiting the Activation of the HRAS/PI3K/AKT/GSK3β Signaling Axis

Phytotherapy Research, EarlyView.
ABSTRACT Chronic atrophic gastritis (CAG), a widespread gastrointestinal condition, is widely acknowledged as a precursor to gastric cancer (GC). The incidence of CAG has been steadily increasing, yet effective pharmacological interventions remain unavailable. Asiatic acid (AA), a bioactive triterpenoid isolated from Centella asiatica, has demonstrated
Feifei Zhou, Cuiyu Zhu, Wanwan Yuan, Wenkun Peng, Qianqian Xu, Hongli Yang, Ruofan Cao, Ben Wang, Meiqian Wang, Hongwei Xu   +9 more
wiley   +1 more source

Optimization of Microwave-Assisted Extraction of Antihepatotoxic Triterpenoid from Actinidia deliciosa Root and Its Comparison with Conventional Extraction Methods

Food Technology and Biotechnology, 2007
A simple and rapid microwave-assisted extraction (MAE) procedure has been developed and optimized for extracting triterpenoids (TTP) from the Actinidia deliciosa root.
Junjun Guan, Xinpeng Bai, Aiyong Qiu
doaj  

A C35 Carotenoid Biosynthetic Pathway [PDF]

, 2003
Upon coexpression with Erwinia geranylgeranyldiphosphate (GGDP) synthase in Escherichia coli, C30 carotenoid synthase CrtM from Staphylococcus aureus produces novel carotenoids with the asymmetrical C35 backbone.
Arnold, Frances H., Umeno, Daisuke
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