Results 151 to 160 of about 34,874 (291)

Expression of Nerve Growth Factor (NGF), TrkA, and p75NTR in Developing Human Fetal Teeth

Frontiers in Physiology, 2016
Nerve growth factor (NGF) is important for the development and the differentiation of neuronal and non-neuronal cells. NGF binds to specific low- and high-affinity cell surface receptors, respectively, p75NTR and TrkA.
T. Mitsiadis, P. Pagella
semanticscholar   +1 more source

Mutation and polymorphism analysis of the TRKA (NTRK1) gene encoding a high-affinity receptor for nerve growth factor in congenital insensitivity to pain with anhidrosis (CIPA) families [PDF]

, 2000
Yoshiko Miura, Sek Mardy, Yutaka Awaya, Keiji Nihei, F. Endo, I. Matsuda, Yasuhiro Indo   +6 more
  +5 more sources

The relationship between gonadotropin releasing hormone and ovulation inducing factor/nerve growth factor receptors in the hypothalamus of the llama

Reproductive Biology and Endocrinology, 2018
Background A molecule identical to nerve growth factor, with ovulation-inducing properties has been discovered in the seminal plasma of South American camelids (ovulation-inducing factor/nerve growth factor; OIF/NGF).
Rodrigo A. Carrasco, Jaswant Singh, Gregg P. Adams   +2 more
doaj   +1 more source

Blocking the tropomyosin receptor kinase A (TrkA) receptor inhibits pain behaviour in two rat models of osteoarthritis

Annals of the Rheumatic Diseases, 2015
Objectives Tropomyosin receptor kinase A (TrkA) mediates nociceptor sensitisation by nerve growth factor (NGF), but it is unknown whether selective TrkA inhibition will be an effective strategy for treating osteoarthritis (OA) pain.
L. Nwosu, P. Mapp, V. Chapman, D. Walsh
semanticscholar   +1 more source

The dynamics of trkA expression in the bovine ovary are associated with a luteotrophic effect of ovulation-inducing factor/nerve growth factor (OIF/NGF)

Reproductive Biology and Endocrinology, 2016
BackgroundOvulation-inducing factor in semen (OIF/NGF) influences ovulation and CL form and function in camelids and, remarkably, in cows. To test the hypothesis that the luteotrophic effect of OIF/NGF is mediated by an increase in trkA receptors in the ...
R. Carrasco, Jaswant Singh, G. Adams
semanticscholar   +1 more source

Investigating TrkA Expression in Canine Appendicular Osteosarcoma

Journal of Veterinary Internal Medicine, 2008
Background: The tropomyosin‐related kinase A (TrkA) proto‐oncogene encodes for a receptor that binds with high affinity to the neurotrophin ligand, nerve growth factor (NGF). Intracellular signaling mediated by the TrkA/NGF axis orchestrates neuronal cell differentiation, mitogenesis, and survival. Interestingly, TrkA also is expressed by bone forming
T M, Fan, A M, Barger, I T, Sprandel, R L, Fredrickson   +3 more
openaire   +2 more sources

A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells. [PDF]

, 2019
Elevated glucose consumption is fundamental to cancer, but selectively targeting this pathway is challenging. We develop a high-throughput assay for measuring glucose consumption and use it to screen non-small-cell lung cancer cell lines against ...
Chen, Bao Ying, Clark, Peter M, Damoiseaux, Robert, Ghezzi, Chiara, Ribalet, Bernard, Wong, Alicia   +5 more
core   +1 more source

The trkA Receptor Mediates Growth Cone Turning toward a Localized Source of Nerve Growth Factor [PDF]

, 1997
Gianluca Gallo, Frances Lefcort, Paul C. Letourneau   +2 more
openalex   +1 more source

Identification and Characterization of an Activating TrkA Deletion Mutation in Acute Myeloid Leukemia [PDF]

, 2000
Gary W. Reuther, Que T. Lambert, Michael A. Caligiuri, Channing J. Der   +3 more
openalex   +3 more sources

The Csk Homologous Kinase Associates with TrkA Receptors and Is Involved in Neurite Outgrowth of PC12 Cells [PDF]

, 1999
Hiroshi Yamashita, Shalom Avraham, Shuxian Jiang, Ivan Đikić, Hava Avraham   +4 more
openalex   +1 more source