Results 181 to 190 of about 45,835 (229)
Cross‐kingdom RNA interference as a unifying mechanism in plant–microbe interactions
New Phytologist, Volume 251, Issue 6, Page 3066-3068, September 2026.
Summia Gul, An‐Po Cheng
wiley +1 more source
NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu +11 more
wiley +1 more source
tRNA-derived fragments: mechanism of gene regulation and clinical application in lung cancer. [PDF]
Wu F +5 more
europepmc +1 more source
NAT10‐Mediated ac4C Modification of circANKRD12 Reprograms the Tumor Microenvironment
NAT10‐dependent acetylation of circANKRD12 drives translation of the circANKRD12_354aa protein, which binds HDAC2 to stabilize c‐Myc via deubiquitination, promoting multiple myeloma (MM) cell proliferation. Concurrently, the circANKRD12‐HDAC2 axis suppresses H3ac‐mediated transcription of IFN‐γ, TNF‐α, and GZMB in NK cells, leading to NK cell ...
Jiale Zhang +8 more
wiley +1 more source
G‐Quadruplexes: Structural Diversity and Emerging Roles in Biomolecular Condensation
G‐quadruplexes (G4s) fold into diverse intra‐ and intermolecular structures, positioning them as emerging regulators of biomolecular condensation. Mechanistically, G4s autonomously form condensates, act as structural platforms to initiate and stimulate condensation, or induce phase transitions.
Wenmeng Wang +5 more
wiley +1 more source
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang +14 more
wiley +1 more source
Condensates on the Move: Midbody Remnants as Large, Translation‐Competent Extracellular Vesicles
Mitotic cells produce three EV types: exosomes and microvesicles (green/blue) delivering pre‐formed molecules, and midbody remnants (magenta) containing functional ribosomes and translation machinery within biomolecular condensates. Unlike passive cargo carriers, MBRs actively synthesize proteins after release, transforming from cellular debris to ...
Ahna R. Skop
wiley +1 more source
IMACulate(DE3), an E. coli Strain for High Purity His‐Tagged Protein Purifications
ABSTRACT Immobilised Metal Affinity Chromatography (IMAC) is widely used to purify his‐tagged recombinant proteins from Escherichia coli. However, endogenous contaminants with histidine clusters, such as GFAT and PDH E1 proteins, are often co‐purified with the target protein.
Jia Q. Truong +5 more
wiley +1 more source
Lippia umbellata Cav.: Chemical Composition, Insecticidal, and Antimicrobial Activities
Hexane extracts of Lippia umbellata leaves and flowers contain lupenone, α‐amyrin, and hentriacontane. They exhibit insecticidal activity against Drosophila melanogaster and inhibit AChE in vitro and in silico. Furthermore, the extracts can inhibit the growth of medically important bacteria and yeasts, including multidrug‐resistant strains.
José Guillermo Avila‐Acevedo +11 more
wiley +1 more source

