Results 181 to 190 of about 45,835 (229)

Cross‐kingdom RNA interference as a unifying mechanism in plant–microbe interactions

open access: yes
New Phytologist, Volume 251, Issue 6, Page 3066-3068, September 2026.
Summia Gul, An‐Po Cheng
wiley   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

open access: yesAdvanced Science, Volume 13, Issue 46, 17 August 2026.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu   +11 more
wiley   +1 more source

NAT10‐Mediated ac4C Modification of circANKRD12 Reprograms the Tumor Microenvironment

open access: yesAdvanced Science, Volume 13, Issue 46, 17 August 2026.
NAT10‐dependent acetylation of circANKRD12 drives translation of the circANKRD12_354aa protein, which binds HDAC2 to stabilize c‐Myc via deubiquitination, promoting multiple myeloma (MM) cell proliferation. Concurrently, the circANKRD12‐HDAC2 axis suppresses H3ac‐mediated transcription of IFN‐γ, TNF‐α, and GZMB in NK cells, leading to NK cell ...
Jiale Zhang   +8 more
wiley   +1 more source

G‐Quadruplexes: Structural Diversity and Emerging Roles in Biomolecular Condensation

open access: yesAdvanced Science, Volume 13, Issue 45, 13 August 2026.
G‐quadruplexes (G4s) fold into diverse intra‐ and intermolecular structures, positioning them as emerging regulators of biomolecular condensation. Mechanistically, G4s autonomously form condensates, act as structural platforms to initiate and stimulate condensation, or induce phase transitions.
Wenmeng Wang   +5 more
wiley   +1 more source

5’tRNA-derived fragments modulate β-cell homeostasis and islet macrophage activation in type 2 diabetes

open access: yes
Cosentino C   +22 more
europepmc   +1 more source

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 8, Page 1648-1660, August 2026.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang   +14 more
wiley   +1 more source

Condensates on the Move: Midbody Remnants as Large, Translation‐Competent Extracellular Vesicles

open access: yesBioEssays, Volume 48, Issue 8, August 2026.
Mitotic cells produce three EV types: exosomes and microvesicles (green/blue) delivering pre‐formed molecules, and midbody remnants (magenta) containing functional ribosomes and translation machinery within biomolecular condensates. Unlike passive cargo carriers, MBRs actively synthesize proteins after release, transforming from cellular debris to ...
Ahna R. Skop
wiley   +1 more source

IMACulate(DE3), an E. coli Strain for High Purity His‐Tagged Protein Purifications

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 8, Page 2127-2138, August 2026.
ABSTRACT Immobilised Metal Affinity Chromatography (IMAC) is widely used to purify his‐tagged recombinant proteins from Escherichia coli. However, endogenous contaminants with histidine clusters, such as GFAT and PDH E1 proteins, are often co‐purified with the target protein.
Jia Q. Truong   +5 more
wiley   +1 more source

Lippia umbellata Cav.: Chemical Composition, Insecticidal, and Antimicrobial Activities

open access: yesChemistry &Biodiversity, Volume 23, Issue 8, August 2026.
Hexane extracts of Lippia umbellata leaves and flowers contain lupenone, α‐amyrin, and hentriacontane. They exhibit insecticidal activity against Drosophila melanogaster and inhibit AChE in vitro and in silico. Furthermore, the extracts can inhibit the growth of medically important bacteria and yeasts, including multidrug‐resistant strains.
José Guillermo Avila‐Acevedo   +11 more
wiley   +1 more source

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