Results 91 to 100 of about 298,923 (289)

RNA‐seq analysis of mitochondria‐related genes regulated by AMPK in the human trophoblast cell line BeWo

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Using RNA‐seq and other bioinformatics analyses, three clusters of mitochondria related genes, including aldo‐keto reductase family 1 members B10 and B15 (AKR1B10, AKR1B15), alanyl‐tRNA synthetase 1 (AARS1), mitochondrial ribosomal protein S6 (MRPS6), mitochondrial calcium uniporter dominant negative subunit beta (MCUB) and dihydrolipoamide branched ...
Bin Wu   +6 more
wiley   +1 more source

Disrupted tRNA Genes and tRNA Fragments: A Perspective on tRNA Gene Evolution

open access: yesLife, 2015
Transfer RNAs (tRNAs) are small non-coding RNAs with lengths of approximately 70–100 nt. They are directly involved in protein synthesis by carrying amino acids to the ribosome.
Akio Kanai
doaj   +1 more source

tRNA 3\u27-amino-tailing for stable amino acid attachment. [PDF]

open access: yes, 2018
Amino acids are attached to the tRNA 3\u27-end as a prerequisite for entering the ribosome for protein synthesis. Amino acid attachment also gives tRNA access to nonribosomal cellular activities.
Gamper, Howard, Hou, Ya-Ming
core   +1 more source

Identification of the Micro‐Ribonucleic Acid Profiles of Plant‐Derived Extracellular Vesicles and their Potential Crosskingdom Regulation

open access: yesAdvanced NanoBiomed Research, EarlyView.
The present study employs small RNA sequencing to identify the types and content of microRNAs (miRNAs) in four widely utilized plant‐derived extracellular vesicles (pEVs). The functional annotation reveals that the pEV miRNAs are involved in regulating the progression of human cancer and viral infection, thereby demonstrating the crosskingdom ...
Fei Wang   +7 more
wiley   +1 more source

Nastává éra mezioborových didaktik?

open access: yesPedagogická Orientace, 2005
Jádrem příspěvku je myšlenka konstituování mezioborových didaktik. Jde o reakci na popsanou aktuální problematiku oborových didaktik v době rychlých kurikulárních změn, zejména při zavádění rámcových vzdělávacích programů.
J. Trna
doaj  

Methylated nucleosides in tRNA and tRNA methyltransferases

open access: yesFrontiers in Genetics, 2014
To date, more than 90 modified nucleosides have been found in tRNA and the biosynthetic pathways of the majority of tRNA modifications include a methylation step(s).
Hiroyuki eHori
doaj   +1 more source

The Bipartite Structure of the tRNA m\u3csup\u3e1\u3c/sup\u3eA58 Methyltransferase from \u3cem\u3eS. cerevisiae\u3c/em\u3e is Conserved in Humans [PDF]

open access: yes, 2005
Among all types of RNA, tRNA is unique given that it possesses the largest assortment and abundance of modified nucleosides. The methylation at N1 of adenosine 58 is a conserved modification, occurring in bacterial, archaeal, and eukaryotic tRNAs. In the
Andersland, Joshua   +3 more
core   +1 more source

Development of a Novel Double‐Layered Wound Dressing Composed of Chitosan Film and Tigecycline‐Loaded Electrospun Polycaprolactone Nanofibers

open access: yesJournal of Applied Polymer Science, EarlyView.
The antibacterial double‐layered wound dressing is fabricated using chitosan (CH) film as the contact layer and tigecycline (Tig)‐loaded poly(ε‐caprolactone) (PCL) nanofibers as the top layer. The CH film has a uniform morphology, and the PCL‐Tig nanofibers show a smooth, randomly oriented, and beadless structure.
Ş. Melda Eskitoros‐Togay   +5 more
wiley   +1 more source

Long noncoding RNA CDKN2B‐AS1 silencing protects against esophageal cancer cell invasion and migration by inactivating the TFAP2A/FSCN1 axis

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 38, Issue 12, Page 1144-1154, December 2022., 2022
Abstract Esophageal cancer (EC) is the most aggressive malignancy in the gastrointestinal tract. Long noncoding RNA cyclin‐dependent kinase inhibitor 2 B antisense RNA 1 (CDKN2B‐AS1) is implicated in EC development. However, the specific mechanisms involved remain poorly defined.
Jia‐Liang Zhu   +6 more
wiley   +1 more source

Genomic Insights Into a Strong Biofilm‐Forming Enterococcus faecalis MTR_EFS01 Strain Isolated From a Shrimp in Bangladesh

open access: yesAnimal Research and One Health, EarlyView.
This study characterizes a multidrug‐resistant and strong biofilm‐forming Enterococcus faecalis strain obtained from a shrimp sample in Bangladesh. ABSTRACT Enterococcus faecalis is known for its ability to form strong biofilms and its role as an opportunistic pathogen. In this study, we screened and characterized a multidrug‐resistant (MDR) and strong
Md. Ashek Ullah   +4 more
wiley   +1 more source

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