Results 111 to 120 of about 191,296 (315)

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

open access: yesCancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu   +16 more
wiley   +1 more source

Lactylation in cancer biology: Unlocking new avenues for research and therapy

open access: yesCancer Communications, EarlyView.
Abstract Lactylation, a newly identified post‐translational modification, plays a multifaceted role in cancer biology by integrating epigenetic and non‐epigenetic mechanisms. This review summarizes the latest research progress on lactylation, including its functions in epigenetic regulation and its broader impact on cellular processes.
Xiaoyu Hou   +6 more
wiley   +1 more source

In Vivo Biosynthesis and Direct Incorporation of Non‐Canonical Amino Acids into Proteins

open access: yesChemBioChem, Accepted Article.
Autonomous cells are engineered biological systems capable of biosynthesising and directly incorporating non‐canonical amino acids (ncAAs) into proteins. These systems have the potential to extend the applicability of the genetic code to enable large‐scale fermentative production of proteins carrying ncAAs.
Ivana Drienovska   +2 more
wiley   +1 more source

Das Regensburger Symposium : ein Bericht

open access: yesBrünner Beiträge zur Germanistik und Nordistik, 2017
Jan Trna
doaj   +1 more source

Rosmarinic Acid Alleviates Radiation-Induced Pulmonary Fibrosis by Downregulating the tRNA N7-Methylguanosine Modification-Regulated Fibroblast-to-Myofibroblast Transition Through the Exosome Pathway

open access: yesJournal of Inflammation Research
Tingting Zhang,1– 3,* Jinglin Mi,1– 3,* Xinling Qin,1– 3,* Zhechen Ouyang,1– 3 Yiru Wang,1– 3 Zhixun Li,1– 3 Siyi He,1– 3 Kai Hu,1– 3 Rensheng Wang,1– 3 Weimei Huang1– 3 1Department of Radiation Oncology, the First Affiliated Hospital of ...
Zhang T   +9 more
doaj  

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