Results 151 to 160 of about 191,296 (315)
Human protein synthesis requires aminoacyl-tRNA pivoting during proofreading. [PDF]
Sapkota D, Sanbonmatsu KY, Girodat D.
europepmc +1 more source
A role for protein‐protein interactions in the maintenance of active forms of aminoacyl‐tRNA synthetases [PDF]
Hieronim Jakubowski
openalex +1 more source
The role of UPR‐related long noncoding RNAs in development of endocrine resistance in breast cancer
Abstract Breast cancer patients who express estrogen receptor α (ER) typically receive endocrine therapy as a first‐line treatment. Most ER‐positive breast cancer patients initially respond to endocrine therapy, but up to 40% of patients develop resistance over time, and the main mechanism is aberrant activation of ER signaling pathways.
Wen Liu, Sahil Gupta, Sanjeev Gupta
wiley +1 more source
Simultaneous in vitro expression of minimal 21 transfer RNAs by tRNA array method. [PDF]
Miyachi R+3 more
europepmc +1 more source
The primary structure of a non‐initiating methionine specific tRNA from brewer's yeast [PDF]
H. Gruhl, Horst Feldmann
openalex +1 more source
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng+4 more
wiley +1 more source
NRF2 signalling in cytoprotection and metabolism
The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing cytoprotective mechanism, because KEAP1 serves as a biosensor for electrophiles by using its reactive thiols and NRF2 is a transcriptional factor regulating genes involved in sulfur ...
Shohei Murakami+4 more
wiley +1 more source
Nanopore sequencing of intact aminoacylated tRNAs. [PDF]
White LK+7 more
europepmc +1 more source
Sequence homologies between the tryptophanyl tRNA synthetases of Bacillus stearothermophilus and Escherichia coli [PDF]
Greg Winter, B. S. Hartley
openalex +1 more source
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu+8 more
wiley +1 more source