Results 81 to 90 of about 298,923 (289)

Over two decades of research on the marine RNA virosphere

iMeta, Volume 1, Issue 4, December 2022., 2022
Advances in meta‐omics provide a surge of marine RNA virus information. Deep marine virus discovery contributes greatly to the megataxonomy of RNA viruses. Understanding diversity and biogeography helps reveal the significance of marine RNA viruses, including evolutionary trajectories, hierarchical taxonomy, and ecological importance.
Meng‐en Liao, Yunyi Xie, Mang Shi, Jie Cui   +3 more
wiley   +1 more source

The subnuclear localization of tRNA ligase in yeast [PDF]

, 1987
Yeast tRNA ligase is an enzyme required for tRNA splicing. A study by indirect immune fluorescence shows that this enzyme is localized in the cell nucleus. At higher resolution, studies using indirect immune electron microscopy show this nuclear location
Abelson, John, Clark, Michael W.
core   +1 more source

Inhalable Polymeric Nanoparticle Containing Triphenylphosphanium Bromide‐modified Sonosensitizer for Enhanced Therapy of Acute Bacterial Pneumonia

Advanced Science, EarlyView.
Bacterial pneumonia is the sixth leading cause of death. In this study, an inhalable polymeric nanoparticle NPFCPS‐P is developed, which under US stimulation showed high efficacy in the treatment of acute bacterial pneumonia. This nanoplatform would be much less prone to select bacterial resistance and represented a promising measure for antibiotics ...
Lin Wang, Fangzhou Chen, Nier Wu, Lingfei Hu, Haihua Xiao, Hanchen Zhang, Dongsheng Zhou   +6 more
wiley   +1 more source

Tyll in Brünn: zwischen Gauklern und Mineuren : ein literaturwissenschaftliches und fremdsprachendidaktisches Unterrichtskonzept zu Daniel Kehlmanns Roman in 20 Aufgaben

Brünner Beiträge zur Germanistik und Nordistik, 2019
This paper aims to treat the latest novel TYLL by Daniel Kehlmann with an approach of literary studies as well as to make it didactically useful. With regard to the didactic approach, this contribution seeks to offer literary (recommended) instructions ...
Johannes Köck, Jan Trna
doaj   +1 more source

Analysis of the Role of Aminoacyl tRNA Synthetase Genes in Global Protein Synthesis and mRNA Specific Regulation of Translation in Cancer Cells [PDF]

, 2020
Analysis of the Role of Aminoacyl tRNA Synthetase Genes in Global Protein Synthesis and mRNA Specific Regulation of Translation in Cancer Cells Elyse Nguyen, Depts. of Biology and Chemistry, Dipak Poria, & Esta Sterneck, with Dr. Sarah Williams, Dept. of
Nguyen, Elyse, Poria, Dipak, Sterneck, Esta   +2 more
core   +1 more source

Transfer RNA-derived small RNAs in the cancer transcriptome [PDF]

, 2016
The cellular lifetime includes stages such as differentiation, proliferation, division, senescence and apoptosis.These stages are driven by a strictly ordered process of transcription dynamics.
A Dueck, A Sobala, AE Hall, AM Burroughs, C Cole, C Fricke, D Green, D Haussecker, D Kim, Darrell Green, DM Thompson, DP Bartel, DR Rhodes, FE Nicolas, GL Hager, H Fu, H Goodarzi, I Salaverria, JM Perkel, M Ghildiyal, M Talpaz, MS Pagter de, NC Schopman, O Rechavi, P Adjibade, P Ivanov, P Kumar, P Kumar, Q Wang, R Levitz, RL Maute, S Yamasaki, SC Stearns, T Uchiumi, Tamas Dalmay, U Harms, William D. Fraser, YS Lee, Z Li   +38 more
core   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

Aggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai, Yun Su, Cong Hu, Zehong Peng, Wei Xue, Liang Dong, Tony Y. Hu   +6 more
wiley   +1 more source

Progress and challenges of mRNA vaccines

Interdisciplinary Medicine, Volume 1, Issue 1, January 2023., 2023
As the third‐generation nucleic acid vaccine, the Messenger RNA (mRNA) vaccine stimulates a specific immune response by introducing mRNA expressing the target antigen into the body through a specific delivery system and expressing the corresponding protein.
Liangru Lin, Yusheng Pei, Zhou Li, Dan Luo   +3 more
wiley   +1 more source

Preparation of Translationally Competent tRNA by Direct Chemical Acylation [PDF]

, 2010
Nonsense codon suppression for unnatural amino acid incorporation requires the preparation of a suppressor aminoacyl-tRNA. Chemical acylation strategies are general but inefficient and arduous. A recent report (J. Am. Chem. Soc.
Dougherty, Dennis A., Duffy, Noah H.
core   +2 more sources

The Mechanisms of Codon Reassignments in Mitochondrial Genetic Codes [PDF]

, 2007
Many cases of non-standard genetic codes are known in mitochondrial genomes. We carry out analysis of phylogeny and codon usage of organisms for which the complete mitochondrial genome is available, and we determine the most likely mechanism for codon ...
A Reyes, A Schneider, AM Nedelcu, AM Simpson, AP Sibler, BF Lang, C Gissi, CA Lozupone, CE Bullerwell, D Urbina, DH Ardell, DV Lavrov, DW Schultz, DW Schultz, E Seif, E Talla, EM Denovan-Wright, FHC Crick, G Burger, G Burger, G Burger, H Asahara, HS Kim, J Castrasena, J Matsugi, J Swire, JD Alfonzo, JL Blanchard, JL Boore, K Hancock, K Tomita, Knight, Knight, M Ehara, M Ehara, M Kimura, M Nohara, M Turmel, MAS Santos, MAS Santos, ME Saks, MJ Laforest, MJ Telford, MV Sanchez Puerta, N Spruyt, NJ Savill, Paul G. Higgs, PG Higgs, PG Higgs, PJ Keeling, PS Lovett, R Giegé, R Koszul, RC Morris, S Kerscher, S Matsuyama, S Osawa, S Osawa, S Osawa, S Sengupta, S Yokobori, SE Massey, SG Andersson, SG Andersson, SJ Freeland, Supratim Sengupta, T Muramatsu, Tomita, Tomita, U Kück, Xiaoguang Yang, Y Hayashi-Ishimaru, Y Hayashi-Ishimaru, Y Inagaki, Y Kuchino   +74 more
core   +4 more sources