Results 161 to 170 of about 110,116 (296)
Variation of tRNA modifications with and without intron dependency
Frontiers in GeneticstRNAs have recently gained attention for their novel regulatory roles in translation and for their diverse functions beyond translation. One of the most remarkable aspects of tRNA biogenesis is the incorporation of various chemical modifications, ranging
Sachiko Hayashi
doaj +1 more source
Recent Advances in Chemical Probing Strategies for RNA Structure Determination in Vivo
Chemistry – A European Journal, EarlyView.This Review illustrates how structural probes combined with advanced sequencing technologies are revolutionizing our ability to map RNA structures and interactions within living cells. It highlights the development of innovative strategies tailored to probe RNA structures in particular biological contexts.
Maryana Yarshova +2 more
wiley +1 more source
An Orthogonal Way of Writing the Tubulin Code
Cytoskeleton, EarlyView.ABSTRACT The Elongator complex has long been characterized for its role in tRNA modification and modulation of protein translation. Beyond these established functions, recent findings reveal an unexpected role for Elongator in directly interacting and tuning microtubule dynamics and properties, broadening its biological significance in eukaryotic cells.
Vicente Jose Planelles‐Herrero +1 more
wiley +1 more source
Role of selenium in the pathophysiology of cardiorenal anaemia syndrome
ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai +2 more
wiley +1 more source
Exploration, EarlyView.Schematic illustration of the mechanism underlying the differences between SARA‐susceptible and SARA‐tolerant dairy goats fed a high‐concentrate diet. SARA‐susceptible goats (HCS) exhibit low rumen pH and metabolic decline, characterized by epithelial inflammation.
Jingyi Xu +10 more
wiley +1 more source
A snoRNA-tRNA modification network governs codon-biased cellular states. [PDF]
Proc Natl Acad Sci U S A, 2023 Zhang M +8 more
europepmc +1 more source
iMetaMed, EarlyView.The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang +3 more
wiley +1 more source
Rapid reconstruction of multidrug‐resistant bacterial genomes using CycloneSEQ nanopore sequencing
iMetaOmics, EarlyView.Multidrug‐resistant (MDR) bacteria commonly harbor highly complex genomes enriched with mobile elements and resistance islands, which are challenging to resolve using short‐read sequencing. Here, we evaluated CycloneSEQ, a newly developed Chinese nanopore sequencing platform, for MDR genome reconstruction.
Kai Peng +9 more
wiley +1 more source
iMetaOmics, EarlyView.Estuaries are vital hotspots for antibiotic resistance genes (ARGs) due to substantial antibiotic pollution. Although viruses have been proposed as key reservoirs and important disseminators of ARGs in environments, their contribution to the estuarine antibiotic resistome remains largely unknown.
Xiao‑Qing Luo +9 more
wiley +1 more source
QutRNA2: Robust tRNA modification discovery from Nanopore direct tRNA sequencing
Abstract Transfer RNAs (tRNAs) are essential for protein synthesis and are extensively modified to ensure their structure and function. Direct RNA sequencing with Oxford Nanopore Technologies enables positional modification analysis but is challenged by tRNAs’ short length, redundancy, and dense modifications.
Michael Piechotta +6 more
openaire +1 more source