Results 161 to 170 of about 15,306 (209)

Trophectoderm Mechanics Direct Epiblast Shape Upon Embryo Implantation [PDF]

open access: yesCell Reports, 2021
Implantation is a hallmark of mammalian embryogenesis during which embryos establish their contacts with the maternal endometrium, remodel, and undertake growth and differentiation. The mechanisms and sequence of events through which embryos change their
Magdalena Żernicka-Goetz   +1 more
exaly   +4 more sources

Elf5 Regulation in the Trophectoderm

open access: yesDevelopmental Biology, 2011
Mouse Elf5 is expressed exclusively in the trophectoderm from the late blastocyst stage to postgastrulation. We demonstrate here that the proximal promoter is used for trophectoderm expression but is not sufficient on its own. In transgenic assays, deletion of a differentially methylated region (DMR) within the promoter has no effect on the activation ...
Peter Pfeffer   +2 more
exaly   +3 more sources

GATA2/3-TFAP2A/C Transcription Factor Network Couples Human Pluripotent Stem Cell Differentiation to Trophectoderm With Repression of Pluripotency

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
To elucidate the molecular basis of BMP4-induced differentiation of human pluripotent stem cells (PSCs) toward progeny with trophectoderm characteristics, we produced transcriptome, epigenome H3K4me3, H3K27me3, and CpG methylation maps of trophoblast ...
Nikola Müller   +2 more
exaly   +2 more sources

Number of Biopsied Trophectoderm Cells Is Likely to Affect the Implantation Potential of Blastocysts With Poor Trophectoderm Quality [PDF]

open access: yesFertility and Sterility, 2016
To evaluate whether the developmental potential of the blastocyst is affected by the number of trophectoderm (TE) cells biopsied in preimplantation genetic diagnosis (PGD) cycles.Retrospective study.University-affiliated center.Women underwent PGD cycles of blastocyst biopsy and fluorescence in situ hybridization analysis.Not applicable.Biopsied TE ...
Yi-Fan Gu, De-Hua Cheng, Jing Guo
exaly   +3 more sources

Can Trophectoderm RNA Analysis Predict Human Blastocyst Competency?

open access: yesSystems Biology in Reproductive Medicine, 2019
A systematic review of the literature showed that trophectoderm biopsy could assist in the selection of healthy embryos for uterine transfer without affecting implantation rates.
David Miller   +2 more
exaly   +4 more sources
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Trophectoderm Biopsy in Human Blastocysts

Human Reproduction, 1990
Trophectoderm biopsy was carried out on 47 human blastocysts. A slit was made in the zona pellucida opposite the inner cell mass by micromanipulative techniques. The human blastocyst zona offered more resistance to slitting compared to that of the mouse. After 18-24 h, controlled herniation of the trophectoderm cells was observed.
D H Barlow, A Dokras, I L Sargent
exaly   +3 more sources

Elucidating the behavior of trophectoderm derivatives in mouse implantation

Developmental Cell, 2022
Studying mammalian implantation in utero is difficult, but many in vitro models of peri-implantation development lack contributions from extra-embryonic tissues. Two recently published Developmental Cell papers present biomimetic systems for culturing peri-implantation mouse blastocysts ex vivo. These papers reveal dynamics and developmental impacts of
Aidan H, Terhune, Jianping, Fu
openaire   +2 more sources

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