Hemodynamic changes in pregnancies with impaired fetal growth: A systematic review and meta‐analysis
Maternal cardiovascular adaptation is altered in pregnancies complicated by impaired fetal growth. From the second trimester onwards, lower cardiac output and increased total peripheral vascular resistance emerge, highlighting the need for early hemodynamic monitoring and potential interventions in at‐risk pregnancies.
Britt M. J. G. Kempener +9 more
wiley +1 more source
Expression of Toll-like Receptors 2 and 4 in Subplacental Trophoblasts From Guinea Pigs (Cavia porcellus) Following Infection With Campylobacter jejuni [PDF]
Eric Burrough +5 more
openalex +1 more source
Adhesion molecules in the maternal–fetal interface in healthy pregnancies and preeclampsia
This study revealed elevated levels of adhesion molecules in the maternal circulation and reduced levels in the fetal circulation in preeclampsia. The findings suggest systemic maternal endothelial dysfunction in preeclampsia. Lower fetal adhesion molecule levels warrant further study. Abstract Introduction Adhesion molecules are markers of endothelial
Ingrid Kverndalen Frisch +4 more
wiley +1 more source
A Novel Human Cellular System for Studying Normal Aging and for Anti-Aging Discovery. [PDF]
This study introduces a human cellular aging model using placental trophoblasts (hTSC‐STBs) that mimics key aging features like senescence and genomic instability. It aligns with human tissue aging and responds to anti‐aging treatments, offering a scalable platform to screen potential therapies and bridge lab findings to clinical applications ...
Feng Z +14 more
europepmc +2 more sources
Citation: 'trophoblast' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11327 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Prognostic value of fetal growth and prenatal functional echocardiography in tetralogy of FALLOT
First demonstration that fetal growth and pulmonary peak velocity at third trimester are independent predictors of postnatal outcome in Tetralogy of Fallot. This may enhance the accuracy of prenatal counseling and facilitate more individualized planning for delivery and neonatal care. Abstract Introduction Tetralogy of Fallot (ToF) shows variability in
Laura Nogué +17 more
wiley +1 more source
Peroxisome Proliferator-Activated Receptor-γ and Retinoid X Receptor Signaling Regulate Fatty Acid Uptake by Primary Human Placental Trophoblasts [PDF]
W. Timothy Schaiff +5 more
openalex +1 more source
Evolutionary Analysis of Transcriptional Regulation Mediated by Cdx2 in Rodents
Our study (1) represented a first systematic analysis of species‐specific adaptation in the DNA binding pattern of transcription factor; (2) represented a first study of cis‐regulation between two reproductively isolated species by using a novel allodiploid system; (3) demonstrated a higher conservation of transcriptional output than that of DNA ...
Weizheng Liang +13 more
wiley +1 more source
Non‐coding RNAs (ncRNAs) regulate breast cancer radioresistance via cell cycle, DNA repair and tumour microenvironment pathways. Targeting ncRNAs (e.g., HOTAIR and miR‐155) with RNA‐based therapies (ASOs and CRISPR) shows promise but faces delivery challenges.
Xiaohui Zhao +8 more
wiley +1 more source

