Results 61 to 70 of about 51,241 (234)

Inhibitor of DNA Binding Protein 2 (ID2) Mediates the Anti-Proliferative and Pro-Differentiation Effects of Insulin-like Growth Factor-1 (IGF-1)

Life
In preeclampsia (PE), impaired trophoblast proliferation and differentiation are thought to cause abnormal placentation and subsequent clinical manifestations of the disease, i.e., hypertension, proteinuria, and end-organ damage.
Rebecca Ssengonzi, Yuye Wang, Jiayi Zhou, Yukako Kayashima, W. H. Davin Townley-Tilson, Balaji Rao, Qing Ma, Nobuyo Maeda-Smithies, Feng Li   +8 more
doaj   +1 more source

Longitudinal AMH trajectories, ovarian reserve recovery, and fertility outcomes after multiagent chemotherapy for high‐risk gestational trophoblastic neoplasia: A real‐world cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To characterize anti‐Müllerian hormone (AMH) recovery after multiagent chemotherapy for high‐risk gestational trophoblastic neoplasia (GTN) and evaluate the impact of regimen and hysterectomy. Methods This was a retrospective cohort of 68 high‐risk GTN patients treated with EMA/CO (etoposide, methotrexate, actinomycin D ...
Wei Xue, Tianyi Chen, Yuxiao Wu, Tong Ren, Jun Zhao, Fengzhi Feng, Xirun Wan, Yang Xiang, Junjun Yang   +8 more
wiley   +1 more source

Effects of Human Umbilical Cord Mesenchymal Stem Cells on Human Trophoblast Cell Functions In Vitro

Stem Cells International, 2016
Trophoblast cell dysfunction is involved in many disorders during pregnancy such as preeclampsia and intrauterine growth restriction. Few treatments exist, however, that target improving trophoblast cell function.
Yajing Huang, Yanming Wu, Xinwen Chang, Yan Li, Kai Wang, Tao Duan   +5 more
doaj   +1 more source

Longitudinal blood pressure trajectories before 20 weeks of gestation and adverse outcomes in women with chronic hypertension

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To explore the different patterns in early‐pregnancy mean arterial pressure (MAP) trajectories before 20 weeks of gestation in pregnant women with chronic hypertension, and whether it can stratify risk for adverse perinatal outcomes.
Haoyu Zuo, Yike Yang, Huanyu You, Chunjie Gong, Yan Wang   +4 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

NOSTRIN: A novel modulator of trophoblast giant cell differentiation

Stem Cell Research, 2018
Differentiation-dependent expression of NOSTRIN in murine trophoblast cells prompted investigation on NOSTRIN's function in trophoblast differentiation. We show here that NOSTRIN levels increased in both mouse and rat placenta during gestation.
Shreeta Chakraborty, Rupasri Ain
doaj   +1 more source

First‐Trimester CBC‐Derived Inflammatory Indices for Prediction of Miscarriage: A Retrospective Cohort Study

Journal of Clinical Laboratory Analysis, EarlyView.
Maternal age was an independent predictor of miscarriage, and first‐trimester NLR and SII provided significant incremental predictive value. Because these indices are routinely derived from standard CBC testing without additional cost, they may serve as practical adjuncts to clinical risk factors for early miscarriage risk stratification.
Suchada Wattanaploy, Suchaya Luewan, Theera Tongsong   +2 more
wiley   +1 more source

Analysis of High‐Risk Factors for Failure of Bleeding Control in Enhanced Myometrial Vascularity Treated With Uterine Artery Embolization

Journal of Clinical Ultrasound, EarlyView.
Enhanced Myometrial Vascularity (EMV) is a serious gynecological condition that often leads to abnormal uterine bleeding. Malformation size and involvement of the uterine fundus are significant risk factors. If EMV diameter > 3.85 cm, the bleeding of the patient is more likely to result in failure in UAE treatment.
Linhua Zhu, Yongfang Yue, Lili Cao
wiley   +1 more source

Adaptive Immunity in Marsupials

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol, Hayley J. Stannard, Julie M. Old   +2 more
wiley   +1 more source

Plac1 Expression Pattern at the Mouse Fetomaternal Interface and Involvement in Trophoblast Differentiation

Cellular Physiology and Biochemistry, 2017
Background/Aims: It is well known that Plac1 is a placenta-specific gene; however, its spatiotemporal expression pattern and exact role at t h e mouse fetomaternal interface r e m a i n s unclear. Methods: In situ hybridization (ISH) was used to localize
Yanli Gu, Junhui Wan, Lv Yao, Nan-Ni Peng, Wen-Lin Chang   +4 more
doaj   +1 more source