Prophylactic ureteral stent placement was associated with a reduced risk of urinary tract injury in women with placenta accreta spectrum undergoing peripartum cesarean hysterectomy, independent of prior cesarean number. Abstract Introduction This retrospective cohort study investigated whether preoperative bilateral ureteral stent placement reduces ...
Hasan Berkan Sayal +5 more
wiley +1 more source
Targeted Intracellular Delivery of Amino Acids to Trophoblast Cells Reveals Proteomic Signatures of Cellular Utilisation. [PDF]
Mazey E +11 more
europepmc +1 more source
Livestock Blastoids: In Vitro Blastocyst Models for Embryogenesis and Reproductive Technologies
ABSTRACT Understanding early embryogenesis in livestock remains a persistent bottleneck in both reproductive biology and animal breeding. Work in domestic species has long been limited by restricted access to embryos, ethical considerations, and the complexity of peri‐implantation development, making mechanistic studies difficult.
Cristina A. Martinez‐Serrano, Jun Wu
wiley +1 more source
Trophoblast cells rewire the epigenetic landscape of vascular smooth muscle cells to modulate plasticity: a regulatory axis disrupted in intrauterine growth restriction. [PDF]
Sarkar P, Ain R.
europepmc +1 more source
Metformin suppresses ATF2 expression, activating the PI3K/Akt pathway and promoting Nrf2 nuclear translocation. This upregulates GPX4, inhibiting ferroptosis in trophoblast cells. Erastin blocks system Xc−, depleting GSH and promoting ferroptosis. LY294002 and ML385 inhibit the pathway, validating the mechanism.
Dandan Xia +6 more
wiley +1 more source
Fatty acid transporters in the porcine conceptus and early placenta and the effects of polyunsaturated fatty acids on trophoblast cells. [PDF]
Blitek A, Szymanska M.
europepmc +1 more source
The evolving role of immunotherapy in ovarian cancer
Abstract Ovarian cancer remains a major cause of gynecologic cancer mortality; and, although immune checkpoint inhibitors have transformed treatment in other solid tumors, their activity in ovarian cancer has been limited by tumor heterogeneity, an immunosuppressive tumor microenvironment, and the lack of robust predictive biomarkers.
Ana Carolina Veneziani +2 more
wiley +1 more source
Integrative transcriptomic analysis uncovers the microRNA-centric regulation of Japanese encephalitis virus infection in porcine trophoblast cells. [PDF]
Yang J +10 more
europepmc +1 more source
Integrated quantitative proteomic, phosphoproteomic, and transcriptomic analyses of human trophoblast stem cells identify stage‐specific kinase signaling networks that regulate trophoblast self‐renewal and differentiation into syncytiotrophoblasts and extravillous trophoblasts.
Rajnish Kumar +3 more
wiley +1 more source
Hypoxia regulates epithelial to mesenchymal transition-associated genes in human trophoblast cells by modulating DNA methylation. [PDF]
Choudhury J +7 more
europepmc +1 more source

