In Vitro 3D Model of Human Endometrial Stromal and Trophoblast Cells: Techniques for an Optimized Formation and Cryopreservation of Spheroids. [PDF]
Muthuraj K +5 more
europepmc +1 more source
Embryonic Mediators of Embryo–Uterus Communication, Implantation and Pregnancy
ABSTRACT Successful reproduction in eutherian mammals requires intimate connections between the embryo and uterus, involving adhesion, attachment and placentation, with or without invasion of the endometrium. The complex dialogue between embryo and uterus involves numerous molecules and pathways.
Keith E. Latham
wiley +1 more source
ABSTRACT While molecular signature contributes to sperm quality and fertility potential, sperm may lost key molecules during cryopreservation. Since sperm cells are transcriptionally inert and rely on interactions with epididymosomes (epEVs) to acquire molecules, herein, we investigated the effects of the addition of epEVs to the cryopreservation ...
Laura Gabrielli Haupenthal +9 more
wiley +1 more source
Disruption of the Placenta-Brain Axis in Transgenic Mice Lacking Serotonin Transporter (SERT) in Trophoblast Cells. [PDF]
Ellenberger DT +10 more
europepmc +1 more source
Altered Distribution of CD14+ Macrophages and Reduced ROS Activity in Preeclamptic Placentas
ABSTRACT Problem Pregnancy requires a delicate balance between maternal immune tolerance and protective responses, with macrophages playing a pivotal role in placental development and immune regulation. Preeclampsia, a hypertensive disorder that affects 5%–8% of pregnancies, is associated with immune dysregulation, oxidative stress, and impaired ...
Luis Donis‐Maturano +5 more
wiley +1 more source
CRISPR/Cas9-mediated gene editing in trophoblast cells via mechanoporation for preeclampsia insight. [PDF]
Morshedi Rad D +7 more
europepmc +1 more source
In pregnant women with new‐onset hypertension starting antihypertensives, some achieve tight BP control within a week (Group 1‐blue line), while others respond slower (Group 2‐red line). Group 1 showed higher Log10PLGF levels, but Log10sFlt‐1 did not differ between groups. Over time, Log10PLGF declined in both groups, while Log10sFlt‐1 remained stable.
Edward Tyrell +4 more
wiley +1 more source
Effects ofexosome miRNA-369-3p on the biological behavior of trophoblast cells in gestational diabetes. [PDF]
Yang L +5 more
europepmc +1 more source
The presence of basal plate myometrial fibers was associated with higher rates of placenta‐related pregnancy disorders and abnormal placental attachment in subsequent pregnancies, but heterogeneity in the data was found due to variable inclusion criteria, sampling methods, and reported outcomes.
Eric Jauniaux +3 more
wiley +1 more source
Immunohistochemical Analysis of IRE1 and PERK Expression in Extravillous Trophoblast Cells of Placenta Accreta Spectrum and Associations With Clinicopathological Parameters. [PDF]
Flindris S +20 more
europepmc +1 more source

