Results 151 to 160 of about 74,627 (274)

A Rare Case of P‐Null Phenotype Identified During Preoperative Screening

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A 46‐year‐old woman scheduled for an elective total abdominal hysterectomy was incidentally found to have a rare P‐null (p) phenotype during routine preoperative testing. Although her ABO/Rh type was A positive, the antibody screen demonstrated strong pan‐reactivity with all panel cells, while the autocontrol was negative, indicating an ...
Alireza Abdollahi, Aysan Nozheh, Hassan Sohrabinia, Samaneh Salarvand   +3 more
wiley   +1 more source

High‐dimensional multiomics reveals perturbations to IL‐6/IL‐6R axis and RUNX3 in CD4+ T cells during third‐trimester pregnancy

Clinical &Translational Immunology, Volume 15, Issue 5, 2026.
Abstract Objectives CD4+ T cells play key roles in regulating immune responses during pregnancy; therefore, we aimed to understand the CD4+ T‐cell surface proteome and transcriptome during pregnancy. Methods CD4+ T cells were analysed in blood and decidua from term pregnancies (> 37 weeks) and non‐pregnant blood.
Jennifer R Habel, Thi H O Nguyen, Natasha de Alwis, E Kaitlynn Allen, Shihan Li, Morgan J Skinner, Jennifer A Juno, Stephen J Kent, Katherine Bond, Deborah A Williamson, Martha Lappas, Natalie J Hannan, Susan Walker, Jan Schroeder, Jeremy Chase Crawford, Paul G Thomas, Katherine Kedzierska, Louise C Rowntree   +17 more
wiley   +1 more source

miR‐146a/b‐5p‐IRAK1‐NF‐κB Axis Regulates Unexplained Recurrent Spontaneous Abortion

Journal of Molecular Recognition, Volume 39, Issue 3, May 2026.
ABSTRACT Unexplained recurrent spontaneous abortion (URSA) remains a prevalent obstetric issue, the underlying causes of which are still not fully understood. MicroRNAs (miRNAs) have the potential to influence URSA through their regulation of gene expression.
Fengping He, Shushu Fan, Lujing Chen, Jiwu Lou, Zhenming Lin, Yulan Liu, Tizhen Yan, Yongmei Zhang   +7 more
wiley   +1 more source

Sonographic Predictors and Long‐Term Reproductive Outcomes in Recurrent Cesarean Scar Pregnancy

Journal of Ultrasound in Medicine, Volume 45, Issue 5, Page 1059-1068, May 2026.
Objectives To explore the ultrasound findings, treatment strategies, and reproductive outcomes in patients with recurrent cesarean scar pregnancy (CSP), providing evidence for clinical management. Methods We identified 1371 confirmed CSP from 1517 initially screened cases (2012–2022) through blinded image review. From 159 subsequent live births in this
Jianan Shi, Xiaoping Gong, Hui Wang, Tiantian Sun, Guanjie Wang, Ping Chen, Mingtao Xiong   +6 more
wiley   +1 more source

Nonclassical MHC‐I Molecules: Emerging Therapeutic Targets in Next‐Generation Immunotherapy

MedComm, Volume 7, Issue 5, May 2026.
Immunotherapies dependent on classical MHC‐I molecules face significant challenges, including extreme polymorphism and frequent downregulation in pathological conditions. This review discusses how nonclassical MHC‐I molecules (HLA‐E, HLA‐F, HLA‐G, CD1, MR1) may potentially circumvent these limitations through restricted genetic diversity, stable ...
Wanlin He, Andrew J. McMichael
wiley   +1 more source

The dynamics of glycosylation in trophoblast cells: development, function, and pregnancy-related disorders. [PDF]

Ann Med
Wang T, Wang Y, Wu Y, Zhang Y, Ma F.
europepmc   +1 more source

Maternal Chrono‐Nutrition and Placental DNA Methylation: The BiSC Study

Molecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
This is the first study to examine how the timing of a mother's meals during pregnancy relates to changes in placental DNA methylation, an epigenetic mark. We found that the timing of the last daily meal was most important. Some epigenetic changes were linked to genes involved in placental function and development, and the long‐term health consequences
Joana Llauradó‐Pont, Sofia Aguilar‐Lacasaña, Marta Cosin‐Tomas, Jordi Julvez, Oren Contreras‐Rodríguez, Manolis Kogevinas, Kyriaki Papantoniou, Elisa Gallo, Barbara N Harding, Martine Vrijheid, Payam Dadvand, Mariona Bustamante, Camille Lassale   +12 more
wiley   +1 more source

Hypoxia regulates epithelial to mesenchymal transition-associated genes in human trophoblast cells by modulating DNA methylation. [PDF]

PLoS One
Choudhury J, Dhole B, Aggarwal K, Singh P, Jala MA, Pandey D, Chaturvedi PK, Gupta S.   +7 more
europepmc   +1 more source

Characteristics of Exosomes and Microbiota in the Decidua of Patients With Early Pregnancy Loss and Their Impact on Trophoblast Cells

Molecular Reproduction and Development, Volume 93, Issue 5, May 2026.
ABSTRACT Early pregnancy loss (EPL) is a common complication with incompletely understood pathogenesis. Recent studies highlight the roles of exosomes and their miRNAs in intercellular communication, and the influence of uterine decidual microbiota on pregnancy outcomes.
Fengping He, Lujing Chen, Jiwu Lou, Yanle Guo, Shushu Fan, Tizhen Yan, Yongmei Zhang   +6 more
wiley   +1 more source

Strongyloides Antigens Alter Cytokines Responses in Toxoplasma gondii-Infected BeWo Trophoblast Cells. [PDF]

Cell Biol Int
Alves FT, Jesus BCG, Diniz MES, Luz LC, Franco PS, Ribeiro VDS, de Carvalho EFG, Barbosa BF, Gonzaga HT.   +8 more
europepmc   +1 more source