Results 131 to 140 of about 46,140 (234)

The 9th Edition of the UICC TNM Classification of Malignant Tumours: Updates and Rationale for Change

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1588-1601, 1 October 2026.
ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley   +8 more
wiley   +1 more source

Trophoblast Extracellular Vesicles Rewire Immunity: A Symptom‐Relief Avenue for Recessive Dystrophic Epidermolysis Bullosa

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
First‐trimester trophoblast EVs are enriched in anti‐inflammatory proteins, lipids, and immunoregulatory miRNAs. EVT‐EVs reprogram monocytes toward a pro‐resolving phenotype and restore immune homeostasis in RDEB, supporting their potential as offering a scalable off‐the‐shelf therapy for chronic inflammatory diseases.
Nell Hirt   +8 more
wiley   +1 more source

The Sleeping Giant: Metabolism and Autophagy in the Generation and Survival of Dormant Polyploid Giant Cancer Cells

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Polyploid giant cancer cells (PGCCs) arise in response to stress and play a critical role in therapy resistance and tumor dormancy. These cells can evade conventional treatments and later contribute to cancer relapse by generating progeny through nonmitotic, amitotic mechanisms.
Silvia Guil‐Luna   +3 more
wiley   +1 more source

Organoids: Current Applications and Future Directions

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Organoids are three‐dimensional multicellular structures derived from stem cells or primary tissues that recapitulate key structural and functional features of native organs. Advances in stem cell biology, biomaterials, and bioengineering have established organoids as powerful platforms for studying human development and disease mechanisms, drug ...
Yueqi Leng   +14 more
wiley   +1 more source

Active surveillance of cervical intraepithelial neoplasia and adverse pregnancy outcomes: A register‐based cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 10, Page 2097-2103, October 2026.
Active surveillance for cervical intraepithelial neoplasia grade 2 is not associated with increased risks of adverse pregnancy outcomes compared to large loop excision of the transformation zone. Abstract Introduction Previous studies have suggested that human papillomavirus (HPV) and HPV‐related disease may be associated with increased risk of adverse
Kirstine Kold Katholm   +6 more
wiley   +1 more source

AOC1 regulates labor initiation through spermidine-induced autophagy of placental trophoblast cells via EIF5A hypusination. [PDF]

open access: yesNat Commun
Chen H   +12 more
europepmc   +1 more source

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