Results 111 to 120 of about 51,707 (295)
Prenatal Diagnosis, EarlyView.ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde +4 more
wiley +1 more source
Pediatric Discovery, EarlyView.Utilizing network toxicology, molecular docking, and dynamic simulations to investigate the potential reproductive toxicity of bisphenol S (BPS). ABSTRACT The aim of this study was to investigate the potential reproductive toxicity of bisphenol S (BPS) and the related molecular mechanisms through a network toxicology approach.
Siyuan Wang +7 more
wiley +1 more source
Of Germ Cells, Trophoblasts, and Cancer Stem Cells
Integrative Cancer Therapies, 2008 The trophoblastic theory of cancer, proposed in the early 1900s by Dr John Beard, may not initially seem relevant to current cancer models and treatments. However, the underpinnings of this theory are remarkably similar to those of the cancer stem cell (CSC) theory.
openaire +2 more sources
Environmental Toxicology, EarlyView.ABSTRACT Diflubenzuron is used as an insect growth inhibitor, and its potential risk to human health was raised owing to the possibility of environmental residues and human exposure. This study aimed to investigate the toxic mechanism of diflubenzuron on trophoblastic cells such as HTR8/SVneo and JEG‐3 cells. We investigated mitochondrial function, Ca2+
Miji Kim +4 more
wiley +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objectives Angiopoietin‐2 (ANGPT2) is known to participate in tumor progression and immune modulation across multiple malignancies. Nevertheless, its expression pattern, prognostic value, and biological function in thyroid cancer (THCA) have not been comprehensively investigated.
Han Chen +5 more
wiley +1 more source
Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report
Allergy, EarlyView.ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter +19 more
wiley +1 more source
Understanding trophoblast development using human embryonic stem cells [PDF]
, 2022 The human placenta is a transient organ that mediates essential feto-maternal interactions that are critical for a successful pregnancy. Trophoblast cells are specialized placental epithelial cells that arise from the trophectoderm, the first lineage to ...
Morey, Robert
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Reproductive Biology and Endocrinology, 2003 Simultaneous determinations of DNA content in cell nuclei and condensed chromatin bodies formed by heterochromatized regions of sex chromosomes (gonosomal chromatin bodies, GCB) have been performed in two trophoblast cell populations of the East-European
Bogdanova Margarita S +3 more
doaj +1 more source
Safety of Venom Immunotherapy in Pregnancy: A Multicentre Study
Allergy, EarlyView.Venom immunotherapy (VIT) during pregnancy, when maintenance dose is well tolerated, can be continued. No increased risk of adverse effects to VIT or safety concerns for the pregnancy or the newborns were observed. No decreased efficacy of VIT, in case of re‐stings, was reported.
Matteo Martini +20 more
wiley +1 more source
, 2009 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Human placental villi are covered by a layer of trophoblast epithelia in direct contact with maternal blood, which exist in a constant steady-state of ...
Widdows, Kate Louise
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