Results 111 to 120 of about 74,627 (274)
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objectives Angiopoietin‐2 (ANGPT2) is known to participate in tumor progression and immune modulation across multiple malignancies. Nevertheless, its expression pattern, prognostic value, and biological function in thyroid cancer (THCA) have not been comprehensively investigated.
Han Chen +5 more
wiley +1 more source
Derivation of Mouse Haploid Trophoblast Stem Cells
Cell Reports, 2019 Summary: Trophoblast stem (TS) cells are increasingly used as a model system for studying placentation and placental disorders. However, practical limitations of genetic manipulation have posed challenges for genetic analysis using TS cells.
Tongtong Cui +14 more
doaj +1 more source
Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas. [PDF]
, 2019 Congenital human cytomegalovirus (HCMV) infection is a leading cause of birth defects worldwide, yet the most effective strategies for preventing virus transmission during pregnancy are unknown.
An, Zhiqiang +8 more
core +1 more source
Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report
Allergy, EarlyView.ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter +19 more
wiley +1 more source
Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids. [PDF]
, 2019 During gastrulation, the pluripotent epiblast self-organizes into the 3 germ layers-endoderm, mesoderm and ectoderm, which eventually form the entire embryo.
Chhabra, Sapna +4 more
core +1 more source
Andrology, EarlyView.ABSTRACT Background Challenges in establishing clinical conventional in vitro fertilization (IVF) in horses include variation in sperm and oocyte quality, which can be affected by mare age. Extended preincubation of stallion spermatozoa has resulted in successful IVF.
Raul A. Gonzalez‐Castro +6 more
wiley +1 more source
Distribution of endothelial cell protein C/activated protein C receptor (EPCR) during mouse embryo development. [PDF]
, 2002 The endothelial cell protein C receptor (EPCR) augments protein C activation by the thrombomodulin.thrombin complex. Deletion of the EPCR gene in mice has been reported to lead to embryonic lethality before embryonic day 10 (E10.0). To identify potential
Crawley, JT +3 more
core
Cell Proliferation, EarlyView.The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang +11 more
wiley +1 more source
Differential expression of microRNA-206 and its target genes in pre-eclampsia [PDF]
, 2015 Objectives: Pre-eclampsia is a multi-system disease that significantly contributes to maternal and fetal morbidity and mortality. In this study, we used a non-biased microarray approach to identify novel circulating miRNAs in maternal plasma that may be ...
Akehurst, Christine +12 more
core +1 more source
The FEBS Journal, EarlyView.Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo +4 more
wiley +1 more source