Results 91 to 100 of about 51,707 (295)
Interferon-gamma alters the phagocytic activity of the mouse trophoblast
Reproductive Biology and Endocrinology, 2005 Interferon-gamma (IFN-gamma) mediates diverse functions in bone marrow-derived phagocytes, including phagocytosis and microbe destruction. This cytokine has also been detected at implantation sites under both physiological and pathological conditions in ...
Abrahamsohn Ises +7 more
doaj +1 more source
International Journal of Cancer, EarlyView.ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley +8 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang +11 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To investigate the association between serum markers and successful conservative management of patients with placenta accreta spectrum (PAS). Methods This was a retrospective case–control study where patients with high‐grade PAS between 2011 and 2025 undergoing conservative leaving the placenta in situ were included.
Ammar Al Naimi +7 more
wiley +1 more source
Decidual macrophage‐mediated ferroptosis in trophoblasts leads to recurrent spontaneous abortion
iMeta, EarlyView.Decidual macrophages from recurrent spontaneous abortion (RSA) patients promote trophoblast ferroptosis and impair trophoblast cell function. Mechanistically, the CXCL2/NF‐κB/HMOX1 axis mediates this effect. Conversely, trophoblasts co‐cultured with RSA decidual macrophages induce pro‐inflammatory macrophage polarization through IL‐6/JAK2/STAT3 ...
Xin Chen +9 more
wiley +1 more source
Targets of Elf5 in Mouse Trophoblast Stem Cells
, 2007 The Placenta is an essential organ for all mammalian embryonic development as it provides the nutritional link between maternal and foetal blood streams.
Deane, Jessica Robyn
core
iNew Medicine, EarlyView.ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu +22 more
wiley +1 more source
The Role of ELf5 in Mouse Trophoblast Stem Cells
, 2010 Elf5 is a DNA transcription factor that has been identified as being involved in placentation of the early embryo. Elf5 is expressed in the extra embryonic ectoderm (ExE), a lineage that contributes to the placenta of the embryo.
Redgate, Emma Louise
core
Cytotoxicity of tumor antigen specific human T cells is unimpaired by arginine depletion. [PDF]
, 2013 Tumor-growth is often associated with the expansion of myeloid derived suppressor cells that lead to local or systemic arginine depletion via the enzyme arginase.
Hundemer, Michael +63 more
core +1 more source
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
Interdisciplinary Medicine, EarlyView.This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source