Results 81 to 90 of about 74,627 (274)

Radial capacity and hemodynamics evaluation in vitro and implantable feasibility validation in vivo of thinner bioresorbable polymer vascular stents

open access: yesBMEMat, EarlyView.
A series of in vitro experiments, numerical simulations and in vivo experiments were conducted to jointly evaluate the effects of different thicknesses of bioabsorbable polymer vascular stents on their radial capacity, hemodynamics and in vivo outcomes.
Chong Chen   +9 more
wiley   +1 more source

Placental crises: disruptive selection and maternal under‐investment as the foundations of mammalian placental evolution and dysfunction

open access: yesBiological Reviews, EarlyView.
ABSTRACT Among the vertebrates, mammals are notable for the dominance of live birth and placental nutrition. The structural diversity of the mammalian placenta is remarkable, despite sharing a single common ancestor and conserved physiological functions.
Davis Laundon   +5 more
wiley   +1 more source

Interferon-gamma alters the phagocytic activity of the mouse trophoblast

open access: yesReproductive Biology and Endocrinology, 2005
Interferon-gamma (IFN-gamma) mediates diverse functions in bone marrow-derived phagocytes, including phagocytosis and microbe destruction. This cytokine has also been detected at implantation sites under both physiological and pathological conditions in ...
Abrahamsohn Ises   +7 more
doaj   +1 more source

Natural killer cells in placentation and cancer: Implications for hypertension during pregnancy [PDF]

open access: yes, 2017
Hypertension during pregnancy is the most common medical condition encountered during gestation. Despite this, knowledge of the mechanisms that underlie the disease and the development of new therapies are limited.
Cornelius, Denise C.   +3 more
core   +1 more source

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source

Transient inhibition of MEK/ERK and WNT pathways enhances direct differentiation of primed hPSCs into functional trophoblast stem cells

open access: yesCell Regeneration
The placenta plays a pivotal role in human pregnancy, yet research into placental development has been hindered by limited access to early-stage embryos and ethical constraints.
Qifan Jiang, Ping Liu, Chunlin Chen
doaj   +1 more source

Impact of donor mare and stallion identity on the likelihood of pregnancy after transfer of in vitro produced embryos

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The success of in vitro embryo production (IVEP) is influenced by donor mare and stallion. Objectives To determine whether donor mare and stallion influence the pregnancy rate after transfer of in vitro produced (IVP) blastocysts and to identify factors influencing the likelihood of obtaining one or more pregnancies from a single ...
M. Papas   +11 more
wiley   +1 more source

NATURAL KILLER CELL EFFECTS UPON ANGIOGENESIS UNDER CONDITIONS OF CONTACT-DEPENDENT AND DISTANT CO-CULTURING WITH ENDOTHELIAL AND TROPHOBLAST CELLS

open access: yesМедицинская иммунология, 2019
Regulation of angiogenesis in the utero-placental bed determines adequate trophoblast invasion, placenta formation and development, as well as successful course of pregnancy.
Kseniya Markova   +6 more
doaj   +3 more sources

VIP contribution to the decidualization program: regulatory T cell recruitment [PDF]

open access: yes, 2014
During early pregnancy, the human uterus undergoes profound tissue remodeling characterized by leukocyte invasion and production of proinflammatory cytokines, followed by tissue repair and tolerance maintenance induction.
Agüero, Mariana   +5 more
core   +1 more source

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang   +11 more
wiley   +1 more source

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